HRA007453
Title:
No microorganism was detected in amniotic fluid of healthy pregnancies from the second trimester to the delivery
Release date:
2024-05-21
Description:
In cohort 1, the bacterial load and community structure in the second trimester AF samples were indistinguishable from negative controls. Although marginally higher bacterial loads and different bacterial communities were observed in the delivery AF samples compared to negative controls, these bacterial DNA signals were not considered biologically functional due to the absence of maternal inflammatory responses. In cohort 2, the bacterial load and community structure of the second trimester AF samples differed significantly from those of negative controls, with Ureaplasma and Lactobacillus identified as the most prevalent genera against negative controls.
Data Accessibility:   
Open access
BioProject:
Study type:
Human metagenome
Individuals & samples
Files
Submitter:   Liu Yu / beginning1001@163.com
Organization:   Peking University First Hospital
Submission date:   2024-05-20