HRA008285
Title:
Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in Pituitary neuroendocrine tumors
Release date:
2024-08-16
Description:
In this study, we performed single-cell (n=87,287) RNA sequencing on cases of bone-invasive PitNETs and cases of non-bone-invasion PitNETs (Non-BI PitNETs). We established a cellular atlas of the immune microenvironment specific to bone-invasive PitNETs and identified a novel subset of macrophages.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
pituitary adenoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
Bone-invasive PitNETs
Contact person:
Li Chuzhong
Email:
lichuzhong@ccmu.edu.cn
Description:
In this study, we conducted single-cell transcriptomic and spatial transcriptomic profiling of BI PitNETs and Non-BI PitNETs samples to delineate differences in their immune microenvironments.
Individuals & samples
Submitter:   Li Chuzhong / lichuzhong@ccmu.edu.cn
Organization:   Beijing Neurosurgical Institute
Submission date:   2024-08-14
Requests:   2