Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in Pituitary neuroendocrine tumors
Release date:
2024-08-16
Description:
In this study, we performed single-cell (n=87,287) RNA sequencing on cases of bone-invasive PitNETs and cases of non-bone-invasion PitNETs (Non-BI PitNETs). We established a cellular atlas of the immune microenvironment specific to bone-invasive PitNETs and identified a novel subset of macrophages.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
In this study, we conducted single-cell transcriptomic and spatial transcriptomic profiling of BI PitNETs and Non-BI PitNETs samples to delineate differences in their immune microenvironments.
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