SPLiCR-seq: A CRISPR-Based Screening Platform for RNA splicing Identifies Novel Regulators of IRE1-XBP1 Signaling Under ER Stress
Release date:
2025-03-06
Description:
Here, we present SPLiCR-seq (SPLicing regulator identification through CRISPR screening), a high-throughput CRISPR screening platform that enables direct measurement of RNA splicing outcomes for pooled genetic perturbations, overcoming limitations of traditional fluorescence-based approaches.
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Submitter: Tian Ruilin / tianrl@sustech.edu.cn
Organization: Southern University of Science and Technology
Submission date: 2025-03-06
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