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HRA010943
   HRA010943.xlsx
Title:
scRNA-seq of immunological features in pediatric HLH
Release date:
2025-06-04
Description:
In the context of Epstein-Barr virus (EBV)-related disorders, EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH) emerges as a life-threatening syndrome, contrasting sharply with the self-limiting nature of infectious mononucleosis (IM). Despite this, our understanding of the immune dysregulation mechanisms in EBV-HLH remains incomplete. Leveraging single-cell RNA sequencing (scRNA-seq) technology, this study aims to elucidate the unique immunological characteristics of EBV-HLH, by comparing the immune profiles of children with IM and their healthy peers
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA035320
Study type:
Disease Study
Disease name:
hemophagocytic lymphohistiocytosis
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC005362
DAC name:
DAC_YangLab
Contact person:
Yang Minghua
Email:
yangminghua@csu.edu.cn
Description:
Department of Pediatrics, Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China.
Individuals & samples
Files
Request Data
Submitter:   Yang Minghua / yangminghua@csu.edu.cn
Organization:   The Third Xiangya Hospital of Central South University
Submission date:   2025-03-10
Requests:   13