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HRA012761
   HRA012761.xlsx
Title:
Residual tumor cells promote metastasis after insufficient radiofrequency ablation by educating CD177hiPAD4hi neutrophils
Release date:
2025-10-18
Description:
Radiofrequency ablation (RFA) has been the most promising local treatment for colorectal liver metastases, based on its advantage in obtaining complete tumor destruction. However, tumor progression after RFA still severely restricts patient prognosis, and its molecular mechanism remains to be further explored. Here, we demonstrated that heat-stressed residual tumor cells after insufficient RFA (iRFA) led to lung metastases. We collected human liver metastasis samples before and after iRFA, performed RNA sequencing, and analyzed the molecular changes associated with iRFA treatment.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA033119
Study type:
Disease Study
Disease name:
colon cancer
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC002154
DAC name:
NFHZLK_DAC
Contact person:
Liao Wangjun
Email:
liaowj@smu.edu.cn
Description:
RNA-seq data from the Department of Oncology, Nanfang Hospital.
Individuals & samples
Files
Request Data
Submitter:   Liao Wangjun / liaowj@smu.edu.cn
Organization:   Nanfang Hospital, Southern Medical University
Submission date:   2025-08-08
Requests:   -