LMO7-mediated POLR2A degradation promotes cellular senescence through the MDM4/p53/p21 axis
Release date:
2025-10-07
Description:
To investigate the regulatory role of the POLR2A gene in cellular senescence, we knocked down the POLR2A gene in HFF1 cells, extracted RNA for RNA-seq analysis, and also extracted RNA from replicative senescent HFF1 P40 cells for RNA-seq analysis.
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Individuals & samples
Files
Submitter: Lei Haixin / haixinlei@dmu.edu.cn
Organization: Institute of Cancer Stem Celll,Dalian Medical University
Submission date: 2025-10-06
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HRA013617.xlsx