CRISPR screening reveals that SMAD1 drives Paneth-like state transition and therapy resistance
Release date:
2025-10-11
Description:
LS174T cell lines cultured as 3D tumor spheroids. We conducted an unbiased CRISPR knockout screen targeting 1,741 human TFs using a library of 17,394 single-guide RNAs (sgRNAs) and 300 negative controls.
Note: HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client) or Asepra Command Line.
Individuals & samples
Files
Submitter: Gao Yijun / gaoyj@sysucc.org.cn
Organization: Sun Yat-sen University Cancer Center
Submission date: 2025-10-10
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HRA013731.xlsx