RNA sequencing data of p57 overexpression in Hep3B cells versus the control group
Release date:
2025-11-15
Description:
To define the tumor-intrinsic functions of p57 (CDKN1C) in hepatocellular carcinoma, we generated Hep3B cells with stable p57 overexpression and performed RNA sequencing. This dataset reveals the transcriptional landscape associated with p57 restoration, offering mechanistic insights into how this endogenous CDK inhibitor modulates cell-cycle regulation, DNA integrity, and immune-related signaling in HCC.
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Individuals & samples
Files
Submitter: Guo Hui / guohui@xjtufh.edu.cn
Organization: The Second Affiliated Hospital of Xi'an Jiaotong University
Submission date: 2025-11-11
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HRA014583.xlsx