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HRA016167
   HRA016167.xlsx
Title:
Next-Generation Sequencing Reveals the Distinct Mutational Landscape of SMARCA4-Deficient Lung Cancer
Release date:
2026-01-21
Description:
The aim of this study is to clarify the molecular mutation characteristics of SMARCA4 deficient lung cancer using next generation sequencing. NGS sequencing was used to analyze the gene expression profile of SMARCA4-deficient lung cancer patients, and the association between gene mutation sites and SMARCA4 expression was analyzed. The pathological characteristics of SMARCA4 deficient lung cancer were analyzed by immunohistochemistry. Patients with SMARCA4 deficient lung cancer have unique immunohistochemical characteristics, and the SMARCA4 gene is involved in the occurrence and development of tumors through different mutation modes.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA055910
Study type:
Cohort Study
Disease name:
lung cancer
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC008030
DAC name:
Hunan Provincial People Hospital
Contact person:
Yang Feicheng
Email:
yfc1387@163.com
Description:
The Data Access Committee consists of the principal investigators and authorized members of the project Next-Generation Sequencing Reveals the Distinct Mutational Landscape of SMARCA4 Deficient Lung Cancer, including Feicheng Yang and Yanchun Li, from Hunan Provincial People s Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, China. The DAC reviews and approves access requests for controlled human genomic and clinical data in compliance with informed consent, ethical approval, and data protection regulations.
Individuals & samples
Files
Request Data
Submitter:   Yang Feicheng / yfc1387@163.com
Organization:   Hunan Provincial Peoples Hospital
Submission date:   2026-01-14
Requests:   -