ICG is a curated knowledgebase of internal control genes (or reference genes) for RT-qPCR normalization in a variety of species. Based on literature curation, ICG provides a comprehensive collection of high-quality experimentally verified internal control genes and their application scenarios for both model and non-model organisms.

Nothing great is ever accomplished in isolation. – Yo-Yo Ma

e.g., Human; 9606; GAPDH; YLS8; Cancer; Hormone Treatments; COVID-19
Data Growth


To be Curated
PMID Year Journal Title

Joining ICG

ICG allows any user to view and search but only registered users can add and edit content.
To become a registered user, please email the ICG Team at icg(AT)big.ac.cn to tell us your preferred login name, real name, research interests, etc., and we will set up an account for you.
Please also spread this news to anyone who might be of interest.

How to Cite

The ICG project has been published in Nucleic Acids Research. To cite us, please refer to the following publication:

ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization. Nucleic Acids Res. 2018. 46(D1), D121-D126 [PMID:29036693]