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Home Species Homo sapiens
COVID-19

Basic Information

Homo sapiens / COVID-19
Species: Human
Category: Human Non-cancer Disease Studies
Description: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2),has led to millions of confirmed cases and deaths worldwide. Efficient diagnostic tools are in high demand, as rapid and large-scale testing plays a pivotal role in patient management and decelerating disease spread. The current management of COVID-19 is based generally on supportive therapy and treatment to prevent respiratory failure. The effective option of antiviral therapy and vaccination is currently under evaluation and development.

Gene Summary

MicroRNA

ICG00153-110
miR-186-5p miR-186-5p

mRNA

ICG00153-105
CypA TBP

Studies (2)

ICG00153-105

COVID-19
Non-cancer Disease Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
CypA Cytochrome
Disease Severity
SARS-CoV-2 Infection
COVID-19
 NM_021130
F: GTCAACCCCACCGTGTTCTTC
R: TTTCTGCTGTCTTTGGGACCTTG
 - 60 SYBR
TBP TATA-binding Protein
Disease Severity
SARS-CoV-2 Infection
COVID-19
 NM_003194
F: CAGTGACCCAGCAGCATCACT
R: AGGCCAAGCCCTGAGCGTAA
 - 60 SYBR

Molecular Types:

mRNA

Evaluation Methods

geNorm
NormFinder
BestKeeper

Contact

Name: Vikram Sainia
Email: vikram@aiims.edu
Institution: Laboratory of Infection Biology and Translational Research, Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India

Reference

Selection of Ideal Reference Genes for Gene Expression Analysis in COVID-19 and Mucormycosis.
Kumar S, Ahmad A, Kushwaha N, Shokeen N, Negi S, Gautam K, Singh A, Tiwari P, Garg R, Agarwal R, Mohan A, Trikha A, Thakar A, Saini V.
Microbiology spectrum. 2022-11-15

ICG00153-110

COVID-19
Non-cancer Disease Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
miR-186-5p MiRNA
Peripheral Blood
SARS-CoV-2 Infection
COVID-19
 -
F: Please contact with the researchers for details.
R: Please contact with the researchers for details.
 - - TaqMan
miR-186-5p MiRNA
Peripheral Blood
SARS-CoV-2 Infection
COVID-19
 -
F: Please contact with the researchers for details.
R: Please contact with the researchers for details.
 - - TaqMan

Molecular Types:

MicroRNA

Evaluation Methods

geNorm
NormFinder
BestKeeper

Contact

Name: Claudia C. dos Santos
Email: claudia.santos@utoronto.ca
Institution: Interdepartmental Division of Critical Care Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, Canada

Reference


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