Basic Information

Homo sapiens / HIV
Species: Human
Category: Human Non-cancer Disease Studies
Description: HIV infection has become a global pandemic, affecting communities throughout the world. Ninety percent of people with HIV live in developing countries. In these countries, HIV/AIDS has taken a heavy toll on economic, social, and family structures. It is responsible for a large proportion of adult deaths causing millions of children to be orphaned.

Gene Summary

mRNA

ICG00153-107

Studies (1)

ICG00153-107

HIV
Non-cancer Disease Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)
Size (bp) Annealing Temperature Detection
TBP TATA-binding Protein
Latency-reversing Agent Treatment
HIV
NM_003194
F: CAGTGAATCTTGGTTGTAAACTTGA
R: TCGTGGCTCTCTTATCCTCAT
113 60 SYBR
UBE2D2 Ubiquitin-Conjugating Enzyme
Latency-reversing Agent Treatment
HIV
NM_181838
F: GTACTCTTGTCCATCTGTTCTCTG
R: CCATTCCCGAGCTATTCTGTT
120 60 SYBR
RPL27A Ribosomal Protein L27
Latency-reversing Agent Treatment
HIV
NM_000990
F: AACATGCCATCCAGACTGAG
R: GGTATTTGTCGAAGTTGATCCG
148 60 SYBR

Molecular Types:

mRNA

Evaluation Methods

Contact

Name: Nancie M. Archin
Email: nancie_archin@med.unc.edu
Institution: UNC HIV Cure Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Reference

Defining stable reference genes in HIV latency reversal experiments.
Ceriani C, Streeter GS, Lemu KJ, James KS, Ghofrani S, Allard B, Shook-Sa BE, Margolis DM, Archin NM.
Journal of virology. 2021-03-24