Home
Species
Human Animals Plants Fungi Bacteria
Studies Genes Publications Phylogenetic Tree Statistics API Documentation Contact Us
Home
Browse
Species
Human Animals Plants Fungi Bacteria
Studies Genes Publications
Phylogenetic Tree Statistics API Documentation Contact Us Submit
Home Species Homo sapiens
Non-Glioma Brain Cancer

Basic Information

Homo sapiens / Non-Glioma Brain Cancer
Species: Human
Category: Human Cancer Studies
Description: Non-Glioma Brain Cancer are the most common solid tumors in children, and, unfortunately, many subtypes continue to have a suboptimal long-term outcome. During the last several years, however, remarkable advances in our understanding of the molecular underpinnings of these tumors have occurred as a result of high-resolution genomic, epigenetic, and transcriptomic profiling, which have provided insights for improved tumor categorization and molecularly directed therapies.

Gene Summary

mRNA

ICG00153-94
GAPDH
ICG00153-95
RPL37A EIF2B1

Studies (2)

ICG00153-94

Astrocytomas
Non-Glioma Brain Cancer
Cancer Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
GAPDH Glyceraldehyde-3-Phosphate Dehydrogenase
Gemistocytic Astrocytomas Tissues
Fibrillary Astrocytomas Tissues
Anaplastic Astrocytomas Tissues
Glioblastomas Tissues
 -
F: GAGTCAACGGATTTGGTCGT
R: CATGGGTGGAATCATATTGGA
 - 59 SYBR

Molecular Types:

mRNA

Evaluation Methods

geNorm
NormFinder

Contact

Name: Sylwia M. Gresner
Email: sylwia.gresner@umed.lodz.pl
Institution: Department of Molecular Pathology and Neuropathology, Medical University of Lodz, 92-216 Lodz, Poland

Reference

Selection of reference genes for gene expression studies in astrocytomas.
Gresner SM, Golanska E, Kulczycka-Wojdala D, Jaskolski DJ, Papierz W, Liberski PP.
Analytical biochemistry. 2010-09-16

ICG00153-95

Meningiomas
Non-Glioma Brain Cancer
Cancer Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
RPL37A Ribosomal Protein L37
Meningioma Surgical Specimens
Arachnoidea Tissues
Dura Mater Tissues
 NM_000998.4
F: Hs01102345_m1
R: Hs01102345_m1
 125 60 TaqMan
EIF2B1 Eukaryotic Initiation Factor
Meningioma Surgical Specimens
Arachnoidea Tissues
Dura Mater Tissues
 NM_001414.3
F: Hs00426752_m1
R: Hs00426752_m1
 75 60 TaqMan

Molecular Types:

mRNA

Evaluation Methods

geNorm
NormFinder
BestKeeper

Contact

Name: Christina Pfister
Email: christina.pfister@med.uni-tuebingen.de
Institution: Department of Neurosurgery, University of Tuebingen, Hoppe-Seyler-Str.3, 72076 Tuebingen, Germany

Reference

Selection of suitable reference genes for quantitative real-time polymerase chain reaction in human meningiomas and arachnoidea.
Pfister C, Tatabiga MS, Roser F.
BMC research notes. 2011-08-02