File:Disease2.png
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Trisomy 21 rescue. Euploid cells can arise from a population of trisomy 21 cells by several mechanisms: spontaneous loss of chromosome 21 together with growth advantage of euploid cells [12] (left); induced loss of chromosome 21 using a selectable marker (TKNEO) targeted to the APP gene [8] (middle); or induced silencing of one chromosome 21 by insertion of XIST into the DYRKY1A gene [3] (right).
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 06:56, 14 October 2014 | | 625 × 655 (99 KB) | Linxia (talk | contribs) | Trisomy 21 rescue. Euploid cells can arise from a population of trisomy 21 cells by several mechanisms: spontaneous loss of chromosome 21 together with growth advantage of euploid cells [12] (left); induced loss of chromosome 21 using a selectable mar... |
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