Difference between revisions of "ENST00000441383.1"

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''GACAT1'',gastric cancer associated transcript 1, might serve as a potential biological marker for the clinical diagnosis of gastric cancer.
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==Annotated Information==
 
==Annotated Information==
 
===Transcriptomic Nomeclature===
 
===Transcriptomic Nomeclature===
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Please input transcriptomic nomeclature information here.
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''GACAT1'': gastric cancer associated transcript 1 (HGNC nomenclature)
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AC096655.1-002, LINC00876, "long intergenic non-protein coding RNA 876" <ref name="ref1" />
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===Function===
 
===Function===
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[[File:Observation of the diagnostic value of using GACAT1 as marker.gif|right|thumb|400px|'''Observation of the diagnostic value of using GACAT1 as marker'''<ref name="ref1" />]]
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''GACAT1'' was lowly expressed in gastric cancer and the expression level of ''GACAT1'', or AC096655.1-002, was associated with lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and differentiation, suggesting that ''GACAT1'' might serve as a potential biological marker for the clinical diagnosis of gastric cancer <ref name="ref1" />.
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===Diseases===
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Gastric cancer <ref name="ref1" />
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===Regulation===
 
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===Expression===
 
===Expression===
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[[File:Expression of GACAT1 was down regulated in gastric carcinoma tissues.gif|right|thumb|400px|'''Expression of GACAT1 was down regulated in gastric carcinoma tissues.'''<ref name="ref1" />]]
  
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===Allelic Information and Variation===
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GACAT1 has been found significantly downregulated in gastric cancer tissues compared with paired-adjacent non-tumorous tissues. Its expression level was significantly correlated with lymph node metastasis, distant metastasis, TNM stages, and differentiation <ref name="ref1" />.
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===Evolution===
 
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==Labs working on this lncRNA==
 
==Labs working on this lncRNA==
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Ningbo Yinzhou People's Hospital and the Affiliated Hospital, Ningbo University School of Medicine, Ningbo, 315040, China <ref name="ref1" />.
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==References==
 
==References==
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<references>
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<ref name="ref1">Sun W, Wu Y, Yu X, Liu Y, Song H, Xia T, et al. Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013,34(5):2697-701.</ref>(1）
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</references>
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{{basic|
 
{{basic|
 
tID = ENST00000441383.1|
 
tID = ENST00000441383.1|
 
source = Gencode19|
 
source = Gencode19|
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same = lnc-RGPD4-1:1,NONHSAT073072|
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same = lnc-RGPD4-1:1,NONHSAT073072,''GACAT1'',''AC096655.1-002'', ''LINC00876'', "long intergenic non-protein coding RNA 876"|
 
classification = intergenic|
 
classification = intergenic|
 
length = 540 nt|
 
length = 540 nt|
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sequence = <dnaseq>GCGTTTACAATCCTTTAGCTAGACAGAAAAGTTATCCAAGTCCCCACTCGAACCAGAAAGTCCAGCTGGCTTCACCTCTCAATAGCCTGCCCATCAGCTGTTCTGTTGCCCTGTAGCCTGCTCCAGATTATCAGTGAAATCACCGCAGCCAGAGACCCTTTCTAGAGTCCAGAAACCTGGTCTGCTTCTCTGGGCTAAGCCTCCTTCTGAAGACACCGGAGGAAAATCCCTAGCTTTGGCTTTTCCAGCGTCAAGAGCAGCCTTGCATTCCTGTTCCGGAGCAGAATTAGAACAATTTGATTCTGAATACATTTAAGAATTAAAAAAAAACAAAATAATGTCAGGGACATTTTCTCTTTGTTTCAGTCCTGAGTCCCAAGTCTAGGCCATGCAGACACAGAGAAGACACTATTTTTAAATGAGGTATTAAATGAAATGAGTGTGCAAGCACTTGGCAATCTGATACCTGCTTACCCAGAAGCTTGTTCTGACAGCCTTCTCATTTGAAATCCCAGGAAATATAGATAATTCACTCTGATT</dnaseq>|
 
sequence = <dnaseq>GCGTTTACAATCCTTTAGCTAGACAGAAAAGTTATCCAAGTCCCCACTCGAACCAGAAAGTCCAGCTGGCTTCACCTCTCAATAGCCTGCCCATCAGCTGTTCTGTTGCCCTGTAGCCTGCTCCAGATTATCAGTGAAATCACCGCAGCCAGAGACCCTTTCTAGAGTCCAGAAACCTGGTCTGCTTCTCTGGGCTAAGCCTCCTTCTGAAGACACCGGAGGAAAATCCCTAGCTTTGGCTTTTCCAGCGTCAAGAGCAGCCTTGCATTCCTGTTCCGGAGCAGAATTAGAACAATTTGATTCTGAATACATTTAAGAATTAAAAAAAAACAAAATAATGTCAGGGACATTTTCTCTTTGTTTCAGTCCTGAGTCCCAAGTCTAGGCCATGCAGACACAGAGAAGACACTATTTTTAAATGAGGTATTAAATGAAATGAGTGTGCAAGCACTTGGCAATCTGATACCTGCTTACCCAGAAGCTTGTTCTGACAGCCTTCTCATTTGAAATCCCAGGAAATATAGATAATTCACTCTGATT</dnaseq>|
 
}}
 
}}
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[[Category:Intergenic]]
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[[Category:Intergenic]][[Category:lnc-RGPD4-1]][[Category:NONHSAG028864]][[Category:ENSG00000232991.1]][[Category:Transcripts]]

Latest revision as of 08:41, 5 April 2015

GACAT1,gastric cancer associated transcript 1, might serve as a potential biological marker for the clinical diagnosis of gastric cancer.



Annotated Information

Transcriptomic Nomeclature

GACAT1: gastric cancer associated transcript 1 (HGNC nomenclature)

AC096655.1-002, LINC00876, "long intergenic non-protein coding RNA 876" [1]


Function

Observation of the diagnostic value of using GACAT1 as marker[1]

GACAT1 was lowly expressed in gastric cancer and the expression level of GACAT1, or AC096655.1-002, was associated with lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and differentiation, suggesting that GACAT1 might serve as a potential biological marker for the clinical diagnosis of gastric cancer [1].




Diseases

Gastric cancer [1]


Expression

Expression of GACAT1 was down regulated in gastric carcinoma tissues.[1]

GACAT1 has been found significantly downregulated in gastric cancer tissues compared with paired-adjacent non-tumorous tissues. Its expression level was significantly correlated with lymph node metastasis, distant metastasis, TNM stages, and differentiation [1].


Labs working on this lncRNA

Ningbo Yinzhou People's Hospital and the Affiliated Hospital, Ningbo University School of Medicine, Ningbo, 315040, China [1].



References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Sun W, Wu Y, Yu X, Liu Y, Song H, Xia T, et al. Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013,34(5):2697-701.






Basic Information

Transcript ID

ENST00000441383.1

Source

Gencode19

Same with

lnc-RGPD4-1:1,NONHSAT073072,GACAT1,AC096655.1-002, LINC00876, "long intergenic non-protein coding RNA 876"

Classification

intergenic

Length

540 nt

Genomic location

chr2+:108370568..108438585

Exon number

5

Exons

108370568..108370726,108371938..108372056,108427136..108427196,108436318..108436440,108438508..108438585

Genome context

Sequence
000001 GCGTTTACAA TCCTTTAGCT AGACAGAAAA GTTATCCAAG TCCCCACTCG AACCAGAAAG TCCAGCTGGC TTCACCTCTC 000080
000081 AATAGCCTGC CCATCAGCTG TTCTGTTGCC CTGTAGCCTG CTCCAGATTA TCAGTGAAAT CACCGCAGCC AGAGACCCTT 000160
000161 TCTAGAGTCC AGAAACCTGG TCTGCTTCTC TGGGCTAAGC CTCCTTCTGA AGACACCGGA GGAAAATCCC TAGCTTTGGC 000240
000241 TTTTCCAGCG TCAAGAGCAG CCTTGCATTC CTGTTCCGGA GCAGAATTAG AACAATTTGA TTCTGAATAC ATTTAAGAAT 000320
000321 TAAAAAAAAA CAAAATAATG TCAGGGACAT TTTCTCTTTG TTTCAGTCCT GAGTCCCAAG TCTAGGCCAT GCAGACACAG 000400
000401 AGAAGACACT ATTTTTAAAT GAGGTATTAA ATGAAATGAG TGTGCAAGCA CTTGGCAATC TGATACCTGC TTACCCAGAA 000480
000481 GCTTGTTCTG ACAGCCTTCT CATTTGAAAT CCCAGGAAAT ATAGATAATT CACTCTGATT
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