Difference between revisions of "MT-LIPCAR"

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===Function===
 
===Function===
LIPCAR is a novel biomarker of cardiac remodeling and predicts future death in patients with heart failure.
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LIPCAR is a novel biomarker of cardiac remodeling and predicts future death in patients with heart failure.<ref name="ref1" />
  
 
===Regulation===
 
===Regulation===
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===Expression===
 
===Expression===
LIPCAR are downregulated at baseline, but significantly upregulated later on during the development of HF.
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LIPCAR are downregulated at baseline, but significantly upregulated later on during the development of HF.<ref name="ref1" />
  
 
==Labs working on this lncRNA==
 
==Labs working on this lncRNA==

Revision as of 11:09, 29 June 2016

Annotated Information

Approved Symbol

MT-LIPCAR

Approved Name

mitochondrially encoded long non-coding cardiac associated RNA

Previous Symbols

Synonyms

uc022bqs.1, LIPCAR

Chromosome

mitochondria

OMIM ID

_

Ensembl ID

_

pubmed IDs

24663402

Characteristics

LIPCAR, a long intergenic noncoding RNA predicting cardiac remodeling and survival of patients with HF.[1].

Cellular Localization

A mitochondrial long noncoding RNA.[1].

Function

LIPCAR is a novel biomarker of cardiac remodeling and predicts future death in patients with heart failure.[1]

Regulation

The mitochondrial long noncoding RNA uc022bqs.1 (LIPCAR) was downregulated early after myocardial infarction but upregulated during later stages.[1].

Diseases

  • heart failure

Expression

LIPCAR are downregulated at baseline, but significantly upregulated later on during the development of HF.[1]

Labs working on this lncRNA

  • From the Institute of Molecular and Translational Therapeutic Strategies (IMTTS), IFB-Tx (R.K., I.V., J.F., A.H., T.T.) and REBIRTH Excellence Cluster (T.T.), Hannover Medical School, Hannover, Germany; Inserm, U744, University Lille Nord de France, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Institut Pasteur de Lille, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Centre Hospitalier Régional et Universitaire de Lille, Lille, France (C.B., G.L., P.d.G., F.P.); Faculté de Médecine de Lille, Lille, France (C.B., G.L.); and National Heart and Lung Institute, Imperial College London, London, United Kingdom (T.T.). [1].

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kumarswamy R, Bauters C, Volkmann I, Maury F, Fetisch J, Holzmann A, Lemesle G, de Groote P, Pinet F, Thum T.(2014) Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure.