Difference between revisions of "Main Page"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div> | <div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div> | ||
<div style="padding:0.5em 0.5em;">[[File:web2a.png|center|410px]] | <div style="padding:0.5em 0.5em;">[[File:web2a.png|center|410px]] | ||
| − | The majority of the lncRNA information was initially seeded with a subset of information from [http://www.gencodegenes.org/ GENCODE], [http://www.bioinfo.org/noncode/ NONCODE], [http://www.lncipedia.org/ LNCipedia], and [http://www.lncrnadb.org/ lncRNAdb], and we classified these lncRNAs into seven groups | + | The majority of the lncRNA information was initially seeded with a subset of information from [http://www.gencodegenes.org/ GENCODE], [http://www.bioinfo.org/noncode/ NONCODE], [http://www.lncipedia.org/ LNCipedia], and [http://www.lncrnadb.org/ lncRNAdb], and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']] |
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LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. | LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. | ||
| − | In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated ( | + | In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured LncRNAs]]). |
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We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. | We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. | ||
| − | As a result, we identified '''9,387''' lncRNAs potentially encoding small proteins and | + | As a result, we identified '''9,387''' lncRNAs potentially encoding small proteins and '''2,246''' among them are with high confidence ([[LncRNAWiki:small proteins|lncRNAs and small proteins]], [[Help:Contents#Database content|Help]]). |
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">How to Cite</div> | <div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">How to Cite</div> | ||
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* BIG Data Center Members: [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] ''Nucleic Acids Research'' 2017, accepted and in press. | * BIG Data Center Members: [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] ''Nucleic Acids Research'' 2017, accepted and in press. | ||
* Lina Ma, Vladimir B. Bajic, Zhang Zhang. [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10(6),924-933. | * Lina Ma, Vladimir B. Bajic, Zhang Zhang. [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10(6),924-933. | ||
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Revision as of 02:51, 28 June 2017
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Welcome to LncRNAWiki
105,824 human long non-coding RNAs inside
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Introduction
LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community. Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia
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Disease
 Top 10 Diseases213 Neoplasms 39 Nervous System Diseases 33 Congenital, Hereditary, and Neonatal Diseases 21 Musculoskeletal Diseases 21 Hemic and Lymphatic Diseases 21 Mental Disorders 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases Top 10 Cancers36 Breast Cancer 31 Prostate Cancer 30 Hepatocellular Carcinoma 28 Gastric Cancer 26 Lung Cancer 18 Colorectal Cancer 12 Esophageal Squamous Cell Carcinoma 12 Bladder Cancer 9 Glioma 9 Lung Adenocarcinoma Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases (Disease). Top diseases and top cancers, and the lncRNA numbers are listed. |
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Classification
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Featured lncRNA
 LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated (Featured LncRNAs). |
Small protein
 We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. As a result, we identified 9,387 lncRNAs potentially encoding small proteins and 2,246 among them are with high confidence (lncRNAs and small proteins, Help). |
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How to Cite
If you use any data or information in your work, please cite the following primary publication:
Related publication:
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