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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div> | <div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div> | ||
| − | <div style="padding:0em; font-size:100%">[[:Category:Transcripts| | + | <div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,053]] human long non-coding RNAs inside</div> |
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| − | <div style="padding:0.5em 0.5em;">[[File: | + | <div style="padding:0.5em 0.5em;">[[File:Featured2.png|left|560px|caption]] |
===<u>Top 10 Diseases</u>=== | ===<u>Top 10 Diseases</u>=== | ||
| − | 213 | + | 213 Cancer 39 Nervous System Diseases |
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| − | 39 Nervous System Diseases | ||
| − | 33 Congenital, Hereditary, and Neonatal Diseases | + | 33 Congenital, Hereditary, and Neonatal Diseases 21 Musculoskeletal Diseases |
| − | 21 | + | 21 Hemic and Lymphatic Diseases 21 Mental Disorders |
| − | + | 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases | |
| − | + | 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases | |
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| − | 15 Endocrine System Diseases | ||
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| − | 10 Skin and Connective Tissue Diseases | ||
===<u>Top 10 Cancers</u>=== | ===<u>Top 10 Cancers</u>=== | ||
| − | 46 [[LncRNAWiki:gastric-cancer|Gastric Cancer]] | + | 46 [[LncRNAWiki:gastric-cancer|Gastric Cancer]] 45 [[LncRNAWiki:breast-cancer|Breast Cancer]] |
| − | 45 [[LncRNAWiki: | + | 45 [[LncRNAWiki:lung-adenocarcinoma|Lung Cancer]] 34 [[LncRNAWiki:hepatocellular-carcinoma|Hepatocellular Carcinoma]] |
| − | + | 34 [[LncRNAWiki:prostate-cancer|Prostate Cancer]] 32 [[LncRNAWiki:colorectal-cancer|Colorectal Cancer]] | |
| − | + | 23 [[LncRNAWiki:esophageal-carcinoma|Esophageal Carcinoma]] 15 [[LncRNAWiki:ovarian-cancer|Ovarian Cancer]] | |
| − | + | 14 [[LncRNAWiki:bladder-cancer|Bladder Cancer]] 14 [[LncRNAWiki:glioma|Glioma]] | |
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| − | + | LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured LncRNAs]]). | |
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Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases ([[LncRNAWiki:Disease|Disease]]). | Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases ([[LncRNAWiki:Disease|Disease]]). | ||
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<!-----------------Classification----------------------> | <!-----------------Classification----------------------> | ||
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div> | <div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div> | ||
| − | <div style="padding:0.5em 0.5em;">[[File:web2a.png| | + | <div style="padding:0.5em 0.5em;">[[File:web2a.png|left|410px]] |
The majority of the lncRNA information was initially seeded with a subset of information from [http://www.gencodegenes.org/ GENCODE], [http://www.bioinfo.org/noncode/ NONCODE], [http://www.lncipedia.org/ LNCipedia], and [http://www.lncrnadb.org/ lncRNAdb], and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']] | The majority of the lncRNA information was initially seeded with a subset of information from [http://www.gencodegenes.org/ GENCODE], [http://www.bioinfo.org/noncode/ NONCODE], [http://www.lncipedia.org/ LNCipedia], and [http://www.lncrnadb.org/ lncRNAdb], and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']] | ||
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<!-----------------Small proteins----------------------> | <!-----------------Small proteins----------------------> | ||
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Small proteins</div> | <div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Small proteins</div> | ||
| − | <div style="padding:0.5em 0.5em;">[[File:SmallPRO-1.png| | + | <div style="padding:0.5em 0.5em;">[[File:SmallPRO-1.png|left|330px]] |
We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. | We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. | ||
Revision as of 03:05, 29 June 2017
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Welcome to LncRNAWiki
106,053 human long non-coding RNAs inside
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Introduction
LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community. Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia
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Featured lncRNAs
 Top 10 Diseases213 Cancer 39 Nervous System Diseases 33 Congenital, Hereditary, and Neonatal Diseases 21 Musculoskeletal Diseases 21 Hemic and Lymphatic Diseases 21 Mental Disorders 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases Top 10 Cancers46 Gastric Cancer 45 Breast Cancer 45 Lung Cancer 34 Hepatocellular Carcinoma 34 Prostate Cancer 32 Colorectal Cancer 23 Esophageal Carcinoma 15 Ovarian Cancer 14 Bladder Cancer 14 Glioma
LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated (Featured LncRNAs). Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases (Disease). Top diseases and top cancers, and the lncRNA numbers are listed. |
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Classification
 The majority of the lncRNA information was initially seeded with a subset of information from GENCODE, NONCODE, LNCipedia, and lncRNAdb, and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). Help
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Small proteins
 We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki. As a result, we identified 9,387 lncRNAs potentially encoding small proteins and 2,246 among them are with high confidence (lncRNAs and small proteins, Help). |
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How to Cite
If you use any data or information in your work, please cite the following primary publication:
Related publication:
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