Difference between revisions of "LINC02243"

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LINC02243:long intergenic non-protein coding RNA 2243
 
LINC02243:long intergenic non-protein coding RNA 2243
  
ENST00000441841<ref name="ref1" />
+
ENST00000441841 <ref name="ref1" />
 
===Characteristics===
 
===Characteristics===
LncRNA ENST00000441841 is located on the sense strand of chromosome X.<ref name="ref1" />
+
LncRNA ENST00000441841 is located on the sense strand of chromosome X <ref name="ref1" />.
  
 
===Function===
 
===Function===
ENST00000441841 is enhancer-like lncRNA, which may increase transcription of their nearby coding genes.<ref name="ref1" />
+
ENST00000441841 is enhancer-like lncRNA, which may increase transcription of their nearby coding genes <ref name="ref1" />.
  
 
===Expression===
 
===Expression===
 
[[File:LINC02243-1.JPG|right|thumb|400px|'''RT-qPCR validation reveals significant lncRNA expression differences in LSCC samples compare to the adjacent normal samples'''<ref name="ref1" />.]]
 
[[File:LINC02243-1.JPG|right|thumb|400px|'''RT-qPCR validation reveals significant lncRNA expression differences in LSCC samples compare to the adjacent normal samples'''<ref name="ref1" />.]]
The expression of LncRNA ENST00000441841 is significantly upregulated in early stage LSCC(lung squamous cell carcinoma).<ref name="ref1" />
+
The expression of LncRNA ENST00000441841 is significantly upregulated in early stage LSCC (lung squamous cell carcinoma) <ref name="ref1" />.
 +
 
 
===Diseases===
 
===Diseases===
Lung squamous cell carcinoma<ref name="ref1" />
+
Lung squamous cell carcinoma <ref name="ref1" />
 +
 
 
===Sequence===
 
===Sequence===
 
>NR_134925.1 Homo sapiens long intergenic non-protein coding RNA 2243 (LINC02243), long non-coding RNA
 
>NR_134925.1 Homo sapiens long intergenic non-protein coding RNA 2243 (LINC02243), long non-coding RNA
Line 38: Line 40:
 
==References==
 
==References==
 
<references>
 
<references>
<ref name="ref1">
+
<ref name="ref1">Cheng Z, Bai Y, Wang P, Wu Z, Zhou L, Zhong M, Jin Q, Zhao J, Mao H, Mao H. Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis. Oncotarget. 2017 Feb 21;8(8):13329-13337.</ref>
Cheng Z, Bai Y, Wang P, Wu Z, Zhou L, Zhong M, Jin Q, Zhao J, Mao H, Mao H.
 
Identification of long noncoding RNAs for the detection of early stage lung
 
squamous cell carcinoma by microarray analysis. Oncotarget. 2017 Feb
 
21;8(8):13329-13337.
 
</ref>
 
 
</references>
 
</references>

Latest revision as of 03:44, 29 September 2017

Annotated Information

Name

LINC02243:long intergenic non-protein coding RNA 2243

ENST00000441841 [1]

Characteristics

LncRNA ENST00000441841 is located on the sense strand of chromosome X [1].

Function

ENST00000441841 is enhancer-like lncRNA, which may increase transcription of their nearby coding genes [1].

Expression

RT-qPCR validation reveals significant lncRNA expression differences in LSCC samples compare to the adjacent normal samples[1].

The expression of LncRNA ENST00000441841 is significantly upregulated in early stage LSCC (lung squamous cell carcinoma) [1].

Diseases

Lung squamous cell carcinoma [1]

Sequence

>NR_134925.1 Homo sapiens long intergenic non-protein coding RNA 2243 (LINC02243), long non-coding RNA

000001 AGGGAATGAA GGCTGGCATC TAAACTCAAT CAGCAAAATA AATTCAATAA GGAAGATTTG AAGATCAAAG ACCTTCCTCT 000080
000081 CTCTGGCTTC ACATTTCTCA TCACTAGTTG AAAGCCTGAA AGAACAAAAA AGCTGACCCT TCCCTGAGTA AGAGAGAATT 000160
000161 CTTCCTGCGT GATGATCTTC AATCTGGGAC ATTGACTTTT TTTCTGCCTT TGGCCTGAAA CATTGGCTCT CCCTGGGTCT 000240
000241 CGAGCCTGCG GGCCTTTGGA CTGGAACTAA ATTATCAGCT CTCCTGGGCC TCCAGGTTGT CTATTCACCC TGCAGATCTT 000320
000321 TCAACTTGCC AGACCCCATA ATTATGTGAA CCAATTCATT ATAAAAATAA ATCTCGATTG CTGGCAAGAT GGCCGAACAG 000400
000401 GAACAGCTCC GGCCTGTAGC TCCCAGCGAG ATCGACATAG AAGGCCTAGG TCATCAAGAT GCACAGCACA GGACAGAAGC 000480
000481 CCCTCTAGTC CTGCACCTGG TGACATGGAA CTGCTGTGCT GGTCCACACA GACACAGCCT CCAACCAAGC CTGGCTCCTA 000560
000561 CCCATCACAG TTCTGTAGGC TGCCCATTTG CAGAAGGCCT TCCATCTGAC ACTCCTCCTC GCCTGCTTGT TCTCCAGCCA 000640
000641 TGTTGTGGCC AATTTGCCAT GAGGAGGTTG CAGTGGCCAA GACTGTTGGA AACTGTGCGG TGTAGCTGGG AGAGAAAGGA 000720
000721 CACACTCTAA ATGTTCTTAC TGCCTGTGAC GATGCAGCTA CAGCGATGTA CTAGCTGCTC ACAAGCCTGT TCCTTCTTCC 000800
000801 ATTGTAGGGC ATGAAGAATT CCCTTATCAC TGGGTAAGAA GGGGGAACAG AAGTTTTTCT CATGCCTAAT TTTGCGTTTT 000880
000881 CAGTAAGGTC TTTTTCAGCT TGTCCAGGAG AAACTGGAAA AAAAAAGATA CTTGAAATAA ACTGAAGGAC ATTTAAACAA 000960
000961 AAAAAAAAAA AAAAAAAAAA AA

Labs working on this lncRNA

  • State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Science, Shanghai 200050, China.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Cheng Z, Bai Y, Wang P, Wu Z, Zhou L, Zhong M, Jin Q, Zhao J, Mao H, Mao H. Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis. Oncotarget. 2017 Feb 21;8(8):13329-13337.