Difference between revisions of "LINC01138"
| Line 1: | Line 1: | ||
==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | + | LINC01138C (long intergenic non-protein coding RNA 1138) | |
| − | |||
| − | long intergenic non-protein coding RNA 1138 | ||
===Previous Symbols=== | ===Previous Symbols=== | ||
LINC00875 | LINC00875 | ||
| Line 10: | Line 8: | ||
===Chromosome=== | ===Chromosome=== | ||
1q21.2 | 1q21.2 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_027468 | NR_027468 | ||
| Line 20: | Line 14: | ||
===Disease=== | ===Disease=== | ||
prostate cancer | prostate cancer | ||
| + | ===Expression=== | ||
| + | The expression level of LINC01138 is markedly increased in invasive extraprostatic tumors (pT3a, pT3b and T4 stages) as compared with intraprostatic localized tumors (pT2a , pT2b and pT2c stages).<ref name="ref1" /> | ||
| + | |||
| + | ===Function=== | ||
| + | The high level of LINC01138 is correlated with a short biochemical recurrence-free survival times.<ref name="ref1" /> | ||
| + | LINC01138 promotes the proliferation and inhibited apoptosis of PCa.<ref name="ref1" /> | ||
| + | LINC01138 functions as an oncogenes in prostate cancer.<ref name="ref1" /> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * State Key Laboratory of Genetic Engineering, Shanghai Engineering Research Center Of Industrial Microorganisms, School of Life Science, Fudan University, Shanghai 200433, PR China. | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1">Wan, X., et al., Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer. Oncotarget, 2016. 7(37): p. 60503-60518. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Revision as of 14:19, 13 November 2017
Contents
Annotated Information
Approved Symbol
LINC01138C (long intergenic non-protein coding RNA 1138)
Previous Symbols
LINC00875
Synonyms
FLJ39739
Chromosome
1q21.2
RefSeq(supplied by NCBI)
NR_027468
pubmed IDs
27556357
Disease
prostate cancer
Expression
The expression level of LINC01138 is markedly increased in invasive extraprostatic tumors (pT3a, pT3b and T4 stages) as compared with intraprostatic localized tumors (pT2a , pT2b and pT2c stages).[1]
Function
The high level of LINC01138 is correlated with a short biochemical recurrence-free survival times.[1] LINC01138 promotes the proliferation and inhibited apoptosis of PCa.[1] LINC01138 functions as an oncogenes in prostate cancer.[1]
Labs working on this lncRNA
- State Key Laboratory of Genetic Engineering, Shanghai Engineering Research Center Of Industrial Microorganisms, School of Life Science, Fudan University, Shanghai 200433, PR China.
