Difference between revisions of "LINC01930"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LINC01930 ===Approved Name=== long intergenic non-protein coding RNA 1930 ===Previous Symbols=== _ ===Synonyms=== EU358092 ===C...") |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LINC01930 | + | LINC01930:long intergenic non-protein coding RNA 1930 |
| − | + | ||
| − | long intergenic non-protein coding RNA 1930 | + | EU358092 <ref name="ref1" /> |
| − | === | + | ===Characteristics=== |
| − | + | EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 (chr1:98,399,030–98,407,302; GRCh37/hg19) <ref name="ref1" />. It is 869 bp in length and has two exons <ref name="ref1" />. | |
| − | === | + | |
| − | EU358092 | + | ===Function=== |
| − | === | + | EU358092 shows a potentially important role in the aetiology of schizophrenia, and its expression is modulated in response to psychoactive drug treatment in the human SH-SY5Y neuroblastoma cell line <ref name="ref1" />. |
| − | + | ===Expression=== | |
| − | = | + | [[File:EU358092 exp.jpg|right|thumb|400px|'''Comparison of MIR137 and ''EU358092'' expression in vivo''' <ref name="ref1" />.]] |
| − | + | EU358092 shows a similar expression pattern to that of MIR137, with highest expression restricted to the brain and pituitary gland <ref name="ref1" />. | |
| − | === | + | |
| − | + | ===Disease=== | |
| − | == | + | Schizophrenia <ref name="ref1" /> |
| − | + | ||
| − | == | + | ==Labs working on this lncRNA== |
| − | + | *Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool L69 3BX, UK. | |
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Gianfrancesco O, Warburton A, Collier DA, Bubb VJ, Quinn JP. Novel brain | ||
| + | expressed RNA identified at the MIR137 schizophrenia-associated locus. Schizophr | ||
| + | Res. 2017 Jun;184:109-115. | ||
| + | </ref> | ||
| + | </references> | ||
Latest revision as of 06:34, 17 November 2017
Contents
Annotated Information
Name
LINC01930:long intergenic non-protein coding RNA 1930
EU358092 [1]
Characteristics
EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 (chr1:98,399,030–98,407,302; GRCh37/hg19) [1]. It is 869 bp in length and has two exons [1].
Function
EU358092 shows a potentially important role in the aetiology of schizophrenia, and its expression is modulated in response to psychoactive drug treatment in the human SH-SY5Y neuroblastoma cell line [1].
Expression
Comparison of MIR137 and EU358092 expression in vivo [1].
EU358092 shows a similar expression pattern to that of MIR137, with highest expression restricted to the brain and pituitary gland [1].
Disease
Schizophrenia [1]
Labs working on this lncRNA
- Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool L69 3BX, UK.
