Difference between revisions of "MGAT3-AS1"
Chunlei Yu (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== MGAT3-AS1 ===Approved Name=== MGAT3 antisense RNA 1 ===Previous Symbols=== _ ===Synonyms=== TapSAKI ===Chromosome=== 22q13.1 ==...") |
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | MGAT3-AS1 | + | MGAT3-AS1 (MGAT3 antisense RNA 1) |
| − | |||
| − | MGAT3 antisense RNA 1 | ||
| − | |||
| − | |||
===Synonyms=== | ===Synonyms=== | ||
| − | TapSAKI | + | TapSAKI <ref name="ref1" /> |
===Chromosome=== | ===Chromosome=== | ||
22q13.1 | 22q13.1 | ||
===RefSeq ID=== | ===RefSeq ID=== | ||
NR_126469 | NR_126469 | ||
| − | |||
| − | |||
===Ensembl ID=== | ===Ensembl ID=== | ||
ENSG00000227188 | ENSG00000227188 | ||
| − | === | + | |
| − | + | ===Characteristics=== | |
| + | MGAT3-AS1 is an intronic antisense lncRNA, which is transcribed from a gene located in the genome on chromosome 22 <ref name="ref1" />. | ||
| + | |||
| + | ===Expression=== | ||
| + | MGAT3-AS1 is significantly increased in patients with acute kidney injury (AKI) compared to healthy controls and disease controls <ref name="ref1" />. | ||
| + | |||
| + | ===Function=== | ||
| + | MGAT3-AS1 is an independent predictor of 28-day survival (P < 0.01), and it is enriched in tubular epithelial cells subjected to ATP depletion (P = 0.03) <ref name="ref1" />. | ||
| + | |||
| + | ===Disease=== | ||
| + | acute kidney injury <ref name="ref1" /> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Department of Medicine/Division of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.<ref name="ref1" /> | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> Lorenzen, J.M., et al., Circulating long noncoding RNATapSaki is a predictor of mortality in critically ill patients with acute kidney injury. Clin Chem, 2015. 61(1): p. 191-201. | ||
| + | </ref>(1) | ||
| + | </references> | ||
| + | |||
===Sequence=== | ===Sequence=== | ||
>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA | >gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA | ||
<dnaseq>GCTACTGGTGGTCATCGGGGACGCAGATATGTGTGTCTCCATTTTGCAGATGAGGACATGGAGGCCTCAAGAGGTTAAGTGACTTGCTCAGCCACACACAGCTGATGGGAATGAAACAGACGGAAACGGAGACTCCCCAAGCTGACAGGCGGACTACAGATCTGGGGGTTCTGCTCCAGGCTCAACACAAGTGGCCTGGGCGAGGGAGGGCCTGGTAGACCATGACACCCAGCATCGAGGAATTCTGCTTCCCCAGCAGGCTCAGAAGGAAGAAGTCTGCTTCAGGGGCCAGGCCTGGTCAAAGACTCCATCTTCCCTGGATGGCCAGAGTCAAATCCTTGCAAATCCCGTTCACCATGGAGCAGAGACGAGACCTATGTTACCCAGGCTGTATGTGAATTCCTGGACTCAAGCAATCCTCCCATCTCAGCCTCGTGAGTAGTTGGGACAAGTCTCACACCACCATACCCAGCTTAATTTAATTTGAATTTTAATAGC</dnaseq> | <dnaseq>GCTACTGGTGGTCATCGGGGACGCAGATATGTGTGTCTCCATTTTGCAGATGAGGACATGGAGGCCTCAAGAGGTTAAGTGACTTGCTCAGCCACACACAGCTGATGGGAATGAAACAGACGGAAACGGAGACTCCCCAAGCTGACAGGCGGACTACAGATCTGGGGGTTCTGCTCCAGGCTCAACACAAGTGGCCTGGGCGAGGGAGGGCCTGGTAGACCATGACACCCAGCATCGAGGAATTCTGCTTCCCCAGCAGGCTCAGAAGGAAGAAGTCTGCTTCAGGGGCCAGGCCTGGTCAAAGACTCCATCTTCCCTGGATGGCCAGAGTCAAATCCTTGCAAATCCCGTTCACCATGGAGCAGAGACGAGACCTATGTTACCCAGGCTGTATGTGAATTCCTGGACTCAAGCAATCCTCCCATCTCAGCCTCGTGAGTAGTTGGGACAAGTCTCACACCACCATACCCAGCTTAATTTAATTTGAATTTTAATAGC</dnaseq> | ||
Latest revision as of 08:29, 7 December 2017
Contents
Annotated Information
Approved Symbol
MGAT3-AS1 (MGAT3 antisense RNA 1)
Synonyms
TapSAKI [1]
Chromosome
22q13.1
RefSeq ID
NR_126469
Ensembl ID
ENSG00000227188
Characteristics
MGAT3-AS1 is an intronic antisense lncRNA, which is transcribed from a gene located in the genome on chromosome 22 [1].
Expression
MGAT3-AS1 is significantly increased in patients with acute kidney injury (AKI) compared to healthy controls and disease controls [1].
Function
MGAT3-AS1 is an independent predictor of 28-day survival (P < 0.01), and it is enriched in tubular epithelial cells subjected to ATP depletion (P = 0.03) [1].
Disease
acute kidney injury [1]
Labs working on this lncRNA
- Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Department of Medicine/Division of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.[1]
References
Sequence
>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA
000001 GCTACTGGTG GTCATCGGGG ACGCAGATAT GTGTGTCTCC ATTTTGCAGA TGAGGACATG GAGGCCTCAA GAGGTTAAGT 000080
000081 GACTTGCTCA GCCACACACA GCTGATGGGA ATGAAACAGA CGGAAACGGA GACTCCCCAA GCTGACAGGC GGACTACAGA 000160
000161 TCTGGGGGTT CTGCTCCAGG CTCAACACAA GTGGCCTGGG CGAGGGAGGG CCTGGTAGAC CATGACACCC AGCATCGAGG 000240
000241 AATTCTGCTT CCCCAGCAGG CTCAGAAGGA AGAAGTCTGC TTCAGGGGCC AGGCCTGGTC AAAGACTCCA TCTTCCCTGG 000320
000321 ATGGCCAGAG TCAAATCCTT GCAAATCCCG TTCACCATGG AGCAGAGACG AGACCTATGT TACCCAGGCT GTATGTGAAT 000400
000401 TCCTGGACTC AAGCAATCCT CCCATCTCAG CCTCGTGAGT AGTTGGGACA AGTCTCACAC CACCATACCC AGCTTAATTT 000480
000481 AATTTGAATT TTAATAGC
000081 GACTTGCTCA GCCACACACA GCTGATGGGA ATGAAACAGA CGGAAACGGA GACTCCCCAA GCTGACAGGC GGACTACAGA 000160
000161 TCTGGGGGTT CTGCTCCAGG CTCAACACAA GTGGCCTGGG CGAGGGAGGG CCTGGTAGAC CATGACACCC AGCATCGAGG 000240
000241 AATTCTGCTT CCCCAGCAGG CTCAGAAGGA AGAAGTCTGC TTCAGGGGCC AGGCCTGGTC AAAGACTCCA TCTTCCCTGG 000320
000321 ATGGCCAGAG TCAAATCCTT GCAAATCCCG TTCACCATGG AGCAGAGACG AGACCTATGT TACCCAGGCT GTATGTGAAT 000400
000401 TCCTGGACTC AAGCAATCCT CCCATCTCAG CCTCGTGAGT AGTTGGGACA AGTCTCACAC CACCATACCC AGCTTAATTT 000480
000481 AATTTGAATT TTAATAGC
