Difference between revisions of "CLMAT3"
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===Approved Name=== | ===Approved Name=== | ||
colorectal liver metastasis associated transcript 3 | colorectal liver metastasis associated transcript 3 | ||
| − | = | + | [[File:The CLMAT3 expression levels in 90 paired CRC and normal tissue samples were analyzed via a qRT-PCR assay.png|right|thumb|400px|'''The CLMAT3 expression levels in 90 paired CRC and normal tissue samples were analyzed via a qRT-PCR assay'''<ref name="ref1" />]] |
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===Synonyms=== | ===Synonyms=== | ||
SPARC-AS1 | SPARC-AS1 | ||
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===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_109873 | NR_109873 | ||
| − | === | + | ===Characteristics=== |
| − | + | CLMAT3 is located on human chromosome 14 (chr14:101379770-101381326, hg19) <ref name="ref1" />. | |
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| + | ===Expression=== | ||
| + | CLMAT3 is significantly up-regulated in the cancerous tissues comparing with the normal colorectal tissues, and high CLMAT3 expression strongly correlates with liver metastasis and lymph node metastasis, and shorter median overall survival duration <ref name="ref1" />. | ||
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| + | ===Function=== | ||
| + | CLMAT3 over-expression is significantly associated with colorectal liver metastasis and is an independent predictor of poor survival for patients with colorectal cancer, indicating that CLMAT3 may act as an oncogene <ref name="ref1" />. | ||
| + | ===Disease=== | ||
| + | * colorectal cancer <ref name="ref1" /> | ||
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| + | ==Labs working on this lncRNA== | ||
| + | * Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.<ref name="ref1" /> | ||
| + | * Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200000, People's Republic of China.<ref name="ref1" /> | ||
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| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> Ye, L.C., et al., Aberrant expression of long noncoding RNAs in colorectal cancer with liver metastasis. Tumour Biol, 2015. 36(11): p. 8747-54. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 09:58, 7 December 2017
Contents
Annotated Information
Approved Symbol
CLMAT3
Approved Name
colorectal liver metastasis associated transcript 3
The CLMAT3 expression levels in 90 paired CRC and normal tissue samples were analyzed via a qRT-PCR assay[1]
Synonyms
SPARC-AS1
RefSeq(supplied by NCBI)
NR_109873
Characteristics
CLMAT3 is located on human chromosome 14 (chr14:101379770-101381326, hg19) [1].
Expression
CLMAT3 is significantly up-regulated in the cancerous tissues comparing with the normal colorectal tissues, and high CLMAT3 expression strongly correlates with liver metastasis and lymph node metastasis, and shorter median overall survival duration [1].
Function
CLMAT3 over-expression is significantly associated with colorectal liver metastasis and is an independent predictor of poor survival for patients with colorectal cancer, indicating that CLMAT3 may act as an oncogene [1].
Disease
- colorectal cancer [1]
Labs working on this lncRNA
- Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.[1]
- Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200000, People's Republic of China.[1]
