Difference between revisions of "G2E3-AS1"
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | G2E3-AS1 | + | G2E3-AS1 (G2E3 antisense RNA 1) |
| − | |||
| − | G2E3 antisense RNA 1 | ||
| − | |||
| − | |||
===Synonyms=== | ===Synonyms=== | ||
CAT1647 | CAT1647 | ||
===Chromosome=== | ===Chromosome=== | ||
14q12 | 14q12 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
XR_001750710 | XR_001750710 | ||
| − | = | + | [[File:The expression levels of CAT266, CAT1297 and CAT1647 in other urological tissue types.png|right|thumb|400px|'''The expression levels of CAT266, CAT1297 and G2E3-AS1(CAT1647) in other urological tissue types'''<ref name="ref1" />]] |
| − | |||
===Disease=== | ===Disease=== | ||
Bladder cancer | Bladder cancer | ||
| + | ===Characteristics=== | ||
| + | G2E3-AS1 is significantly enriched in the cytoplasmic fraction. <ref name="ref1" /> | ||
| + | |||
| + | ===Function=== | ||
| + | Knockdown G2E3-AS1 activate apoptotic pathways leading to decrease in migration capacity of bladder cancer cells.<ref name="ref1" /> | ||
| + | |||
| + | ===Expression=== | ||
| + | G2E3-AS1 is up-regulated in bladder cancer. <ref name="ref1" /> | ||
| + | Expression levels of G2E3-AS1 is found to be significantly higher in high grade bladder cancer (p = 0.027).<ref name="ref1" /> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Department of Urology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands <ref name="ref1" /> | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1">Dudek AM, Boer SJ, Boon N, Witjes JA, Kiemeney LALM, Verhaegh GW. Identification of long non-coding RNAs that stimulate cell survival in bladder cancer. Oncotarget. 2017 May 23;8(21):34442-34452. doi:10.18632/oncotarget.16284. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 03:27, 27 January 2018
Contents
Annotated Information
Approved Symbol
G2E3-AS1 (G2E3 antisense RNA 1)
Synonyms
CAT1647
Chromosome
14q12
RefSeq(supplied by NCBI)
XR_001750710
The expression levels of CAT266, CAT1297 and G2E3-AS1(CAT1647) in other urological tissue types[1]
Disease
Bladder cancer
Characteristics
G2E3-AS1 is significantly enriched in the cytoplasmic fraction. [1]
Function
Knockdown G2E3-AS1 activate apoptotic pathways leading to decrease in migration capacity of bladder cancer cells.[1]
Expression
G2E3-AS1 is up-regulated in bladder cancer. [1] Expression levels of G2E3-AS1 is found to be significantly higher in high grade bladder cancer (p = 0.027).[1]
Labs working on this lncRNA
- Department of Urology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands [1]
