Difference between revisions of "PRDM16-DT"

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(Expression)
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ENSG00000177133
 
ENSG00000177133
  
[[File:expression-new.jpg|right|thumb|400px|'''The expression of PRDM16-DT is needed for brown adipogenesis.'''<ref name="ref1" />.]]
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[[File:expression-3.jpg|right|thumb|400px|'''The expression of PRDM16-DT is needed for brown adipogenesis.'''<ref name="ref1" />.]]
  
 
===Function===
 
===Function===

Revision as of 05:31, 10 August 2019

Annotated Information

Name

PRDM16-DT

Alias

lnc-dPrdm16

ID

ENSG00000177133

The expression of PRDM16-DT is needed for brown adipogenesis.[1].

Function

Knockdown PRDM16-DT could impair brown adipocyte differentiation in vitro.[1] The expression of PRDM16-DT is required for iWAT browning

Labs working on this lncRNA

  • Key Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. cmding@gmail.com.

References

  1. 1.0 1.1 Ding C, Lim YC, Chia SY, Walet ACE, Xu S, Lo KA, Zhao Y, Zhu D, Shan Z, Chen Q, Leow MK, Xu D, Sun L. De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis. Nat Commun. 2018 Apr 6;9(1):1329. doi: 10.1038/s41467-018-03754-3. PubMed PMID: 29626186; PubMed Central PMCID: PMC5889397.