Difference between revisions of "PRDM16-DT"
| Line 13: | Line 13: | ||
===Function=== | ===Function=== | ||
Knockdown PRDM16-DT could impair brown adipocyte differentiation in vitro.<ref name="ref1" /> | Knockdown PRDM16-DT could impair brown adipocyte differentiation in vitro.<ref name="ref1" /> | ||
| − | The expression of PRDM16-DT is required for iWAT browning | + | The expression of PRDM16-DT is required for iWAT browning.<ref name="ref1" /> |
| + | lnc-dPrdm16 is a regulator in BAT and during inguinal WAT browning in vivo.<ref name="ref1" /> | ||
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Latest revision as of 05:34, 10 August 2019
Contents
Annotated Information
Name
PRDM16-DT
The expression of PRDM16-DT is needed for brown adipogenesis.[1].
Alias
lnc-dPrdm16
ID
ENSG00000177133
Function
Knockdown PRDM16-DT could impair brown adipocyte differentiation in vitro.[1] The expression of PRDM16-DT is required for iWAT browning.[1] lnc-dPrdm16 is a regulator in BAT and during inguinal WAT browning in vivo.[1]
Labs working on this lncRNA
- Key Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. cmding@gmail.com.
References
- ↑ 1.0 1.1 1.2 1.3 Ding C, Lim YC, Chia SY, Walet ACE, Xu S, Lo KA, Zhao Y, Zhu D, Shan Z, Chen Q, Leow MK, Xu D, Sun L. De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis. Nat Commun. 2018 Apr 6;9(1):1329. doi: 10.1038/s41467-018-03754-3. PubMed PMID: 29626186; PubMed Central PMCID: PMC5889397.
