Difference between revisions of "LUADT1"

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===Ensembl ID===
 
===Ensembl ID===
 
ENSG00000196634
 
ENSG00000196634
 +
 +
===Expression===
 +
LncRNALUADT1 expression was up-regulated in colorectal cancer, and correlated with tumor size, metastasis, and TNM staging <ref name="ref1" />
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===Function===
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LUADT1 regulate cell cycle progression by epigenetically inhibiting the expression of p27.<ref name="ref2" />
  
 
===Sequence===
 
===Sequence===
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<dnaseq>GCAGAAATGGTTTCCGTTCAGCAAATCCACACCAGCAATCCTCTTACAGCAAATTTCCAAGAAACATGGTTGGATAACAGTGCTGGACCTAAAAAAGGTGTTGGCCCACGAGTGCCTCTCTCTCCCTGCCTGAGCTCCCTGACCAGCATGCGTGTGGCCTCCAGGTGTGTTGTCTACCCCCCAGGACCTGCCAAGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGAGGGAAGATCACGAGCTCAAGATATCAAGACCATCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCATGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATCGCTTGAACCTGGGAGGTGCAGGTTGCAACACACTACTAACTCCAGCCTGGGCGACAGAGCAAGACTGTCT</dnaseq>
 
<dnaseq>GCAGAAATGGTTTCCGTTCAGCAAATCCACACCAGCAATCCTCTTACAGCAAATTTCCAAGAAACATGGTTGGATAACAGTGCTGGACCTAAAAAAGGTGTTGGCCCACGAGTGCCTCTCTCTCCCTGCCTGAGCTCCCTGACCAGCATGCGTGTGGCCTCCAGGTGTGTTGTCTACCCCCCAGGACCTGCCAAGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGAGGGAAGATCACGAGCTCAAGATATCAAGACCATCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCATGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATCGCTTGAACCTGGGAGGTGCAGGTTGCAACACACTACTAACTCCAGCCTGGGCGACAGAGCAAGACTGTCT</dnaseq>
  
===Expression===
+
==Labs working on this lncRNA==
LncRNALUADT1 expression was up-regulated in colorectal cancer, and correlated with tumor size, metastasis, and TNM staging <ref name="ref1" />
+
*Department of Coloproctology, The Hangzhou Third Hospital, Hangzhou, China. shenzhong114@sina.com.<ref name="ref1" />
 +
*Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Cancer Institute of Jiangsu Province, Baiziting 42, Nanjing 210009, China.<ref name="ref2" />
  
==Labs working on this lncRNA==
 
*Department of Coloproctology, The Hangzhou Third Hospital, Hangzhou, China. shenzhong114@sina.com.
 
 
==References==
 
==References==
 
<references>
 
<references>
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related to clinicopathology. Eur Rev Med Pharmacol Sci. 2018 Apr;22(8):2282-2286.
 
related to clinicopathology. Eur Rev Med Pharmacol Sci. 2018 Apr;22(8):2282-2286.
 
doi: 10.26355/eurrev_201804_14816. PubMed PMID: 29762830.
 
doi: 10.26355/eurrev_201804_14816. PubMed PMID: 29762830.
 +
</ref>
 +
 +
<ref name="ref2">
 +
Qiu M, Xu Y, Wang J, Zhang E, Sun M, Zheng Y, Li M, Xia W, Feng D, Yin R, Xu
 +
L. A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the
 +
epigenetic suppression of p27. Cell Death Dis. 2015 Aug 20;6:e1858. doi:
 +
10.1038/cddis.2015.203. PubMed PMID: 26291312; PubMed Central PMCID: PMC4558496.
 
</ref>
 
</ref>
 
</references>
 
</references>

Latest revision as of 06:39, 10 August 2019

Annotated Information

Approved Symbol

LUADT1

Approved Name

lung adenocarcinoma associated transcript 1

Chromosome

6q24.3

RefSeq ID

NR_132442

Ensembl ID

ENSG00000196634

Expression

LncRNALUADT1 expression was up-regulated in colorectal cancer, and correlated with tumor size, metastasis, and TNM staging [1]

Function

LUADT1 regulate cell cycle progression by epigenetically inhibiting the expression of p27.[2]

Sequence

>gi|921274084|ref|NR_132442.1| Homo sapiens lung adenocarcinoma associated transcript 1 (LUADT1), long non-coding RNA

000001 GCAGAAATGG TTTCCGTTCA GCAAATCCAC ACCAGCAATC CTCTTACAGC AAATTTCCAA GAAACATGGT TGGATAACAG 000080
000081 TGCTGGACCT AAAAAAGGTG TTGGCCCACG AGTGCCTCTC TCTCCCTGCC TGAGCTCCCT GACCAGCATG CGTGTGGCCT 000160
000161 CCAGGTGTGT TGTCTACCCC CCAGGACCTG CCAAGCACGG TGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCCGAGG 000240
000241 AGGGAAGATC ACGAGCTCAA GATATCAAGA CCATCCTGGC CAACATGGTG AAACCCTGTC TCTACTAAAA ATACAAAAAT 000320
000321 TAGCTGGGCG TGGTGGTGCA TGCCTGTAGT CCCAGCTACT CGGGAGGCTG AGGCAGCAGA ATCGCTTGAA CCTGGGAGGT 000400
000401 GCAGGTTGCA ACACACTACT AACTCCAGCC TGGGCGACAG AGCAAGACTG TCT

Labs working on this lncRNA

  • Department of Coloproctology, The Hangzhou Third Hospital, Hangzhou, China. shenzhong114@sina.com.[1]
  • Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Cancer Institute of Jiangsu Province, Baiziting 42, Nanjing 210009, China.[2]

References

  1. 1.0 1.1 Zhang XF, Zhang Y, Shen Z, Yang GG, Wang HD, Li LF, Liu DC, Qiu JM. LncRNALUADT1 is overexpressed in colorectal cancer and its expression level is related to clinicopathology. Eur Rev Med Pharmacol Sci. 2018 Apr;22(8):2282-2286. doi: 10.26355/eurrev_201804_14816. PubMed PMID: 29762830.
  2. 2.0 2.1 Qiu M, Xu Y, Wang J, Zhang E, Sun M, Zheng Y, Li M, Xia W, Feng D, Yin R, Xu L. A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27. Cell Death Dis. 2015 Aug 20;6:e1858. doi: 10.1038/cddis.2015.203. PubMed PMID: 26291312; PubMed Central PMCID: PMC4558496.