Difference between revisions of "NKILA"
| Line 5: | Line 5: | ||
NF-kappaB interacting long non-coding RNA | NF-kappaB interacting long non-coding RNA | ||
===Disease=== | ===Disease=== | ||
| − | + | melanoma<ref name="ref1" /> | |
===Chromosome=== | ===Chromosome=== | ||
20q13.31 | 20q13.31 | ||
| Line 12: | Line 12: | ||
===Ensembl ID=== | ===Ensembl ID=== | ||
ENSG00000278709 | ENSG00000278709 | ||
| − | === | + | ===Function=== |
| − | + | NKILA suppressed the development of malignant melanoma via the regulation of NF-ĸB and may be a potential therapeutic target in patients with melanoma.<ref name="ref1" /> | |
===Sequence=== | ===Sequence=== | ||
>gi|768311636|ref|NR_131157.1| Homo sapiens NF-kappaB interacting long non-coding RNA (NKILA), long non-coding RNA | >gi|768311636|ref|NR_131157.1| Homo sapiens NF-kappaB interacting long non-coding RNA (NKILA), long non-coding RNA | ||
<dnaseq>AGACCCGGCACCCGCGCAACGGAGGAGGGGCGCTGTGCCCTCTCCCCAACGGCGGTCAGCTTGGAACGCCTGCCCGGCGCACGCCCGGGGCCGGGGAGCCGAACTCGGTGCCAGCCGCACCCGGGCGGGTTGCTGGTGCGCCCTCCCCTCGCCCCCGTCCCTGGGGTCCTTGACCCAGGCTCTTGGGGCTAGCCTATCTTCTGAGGAGCACAAGGTCCCTGGGGGCTCAGGGAAGAGAAATTGGAGAAAGGGGGAGGAAGCCCCCAAGATGGATCACCCATTGCCTGGTTTCGCAGGAGACTGTCCGCCTTCAGTTCTCCAGCAGCTCGGGGATCATGGCCCACTGAACCCCCAAGCGCTTTCACCCGAACCCAAGGAGGACGACCAGGAAAGACGGGAACTCGCGTAGACACGCCCGGAAGCCCTTGTCATGTAAATAGCTGTCGGGGACTGGTGTATTGTCGCCGCCCCAGCCGGCGGGACCTGGGGCGAATCCACACCCATTGTCTGCTGCCCAAGGGGCCTCCGGCTGGGGGGCGCGGCTGCGGAGTTCAAAAGGGGTATGAGCAGGAGGGGTGTACTTTTAGTTCATTAAGTTTTAATTACAGGAGTGCTACAAGAACACATTCTTCAGGTTTAAAAAGATATTAAAATATTACATAAGAGACCTCCCCTCCCTGGCCCACCTCCAGCCTCTTAAAAATTTAGTGTGTCGCCTTTTAGACACTTTCTCAAAGCTTCACTTATTTAACAGGCACTTAAGGAGCACCTACCTGTGCCAGAAACTCTCCAAATATTAACTCAACCTGACACCGACTCAGTGTGGCCGAATATTACTCTCCCCATTTTACAGAGCGGGCAGCTGGTCAAGGAAGTCGCTTGTTGAAAGTCACACAGTGGTGGAGCCTGTGTGCCAACCCAGGACCCTGGGGAGCTGCCTCCCCCTCTCCCACGTAGTCCTGATTCTTTAAGTGTCCACATATTCCTGTAATGCCTGGAGTTTCAGTAATTAGCAGGGACTTAGTGTGTTCAGAGAAAAAAAAAGCTTTTAAAAATTATTGTTACTGTGTTTGTAACAGTTTGGATAGAGAAGGAAAAGCTGGAATTTGGGAAGTGAAGGTGGCCTCGGGGTAGAACTTACCTAGACCAGAGCGAATTCATCCTGAAGAACTCAGAGAAAGCCGGTGCAGGAAGTGGGTTCCCGCTCTCCCTGCACAGGCACAGTGATGCTGCCAGAGCTCTCCCAGAAAGACCAGGAGGCTTGTTCTGGAGAAGTCAAGCCCAGGGATGTGGCTCAGGCTGGTCCAAGCTCTTTGGAGGAGTCCAAGCGTGCCCAGCCCAGAGGGAGGTTCAGAGGCACTGACCGTCTTCTGTTTGGGAGGAGAAGCTCACTCTTGGAGCCACAGCCAGCACTAGGTCAGGACCCAGGCCCCGGCCCAGGAGTGGGGCAATACCCAGCGTCTACCCCAGATGGCACCCTGCTGTGAACTGGGCGCCCTCAGCCCCTGCCTTGAGGAAGGGGCAATACCACCAGCGTGTCTTTTATCAGGGAAGATATTGCTGCAGTTTGGCCGCTGCAACTTAAGAGAAAAGCTAAGGGGTCCCCCAGCATCCCTTGGGGTGCCACTGCAAATACTGGCTGGGCCTGGAGATGACCTGGGTCCCATTCACTTCCTAGGGTGAAGGAGGTCATCATTACCACCCCTGCTTTCAGCCATTTCTTCATTCATTCAATCAACAAACTGGCTGAGCTGCAACCCTGAGCCGGGGAATTCAGCCACTCCAGACACAGCCCCTGCCCTCCGGGAAGTCTCGGGAGACCTGGCTAGTCTGGCTGGGAGAAGTCACACGTTGATTGTCTTGGAAGTGAGATGGCATTTACACAATGGAGGCTGCACTGCCAGCAGGCAAAAATAACCAGTTAATTCAGTGGCTTAAAGAAACCAAACCTACCCACAACGCTTGACCTCCCATTGATCCATCTGCGACACCGGCAGTGGCTACCATTTATTGAGTGCTGATGGTGTCACCTGGGATTGACTTAGTGGTCTCTGGCGCTAGTTCCGAAGTTGATTCTGTCTGGAGAGCTTAATGCAGTGTTCAGACCTCAGGGTCCGAACCTGAGGGTCACCCAAAGATGAGTGGGACATAGCTGTGTGACCTCGGCTGAGTGCTTTCACCTCTCCAACCTCAGTTTCCTCTTCTGCAAAATGGGGTGGCTTCATGGCACCTTCACGTGGTGTGATTGCGAGGAATGAAGGGATCGATGCCTTGCAAGTAGAGGAGAAGGGGCCGGATACATCTTAGTTGTTATGTTATTTAATCATCTTGGCAACCCCGGGAGGGAGGAACCACTATCATTTTATTTTCCATTTTGCAGTTGAGGACAATGATGATTCCAGCACAGACAGGGCCCCTGACGGGGCAGTAGGAAAGGAGAATTGCTTTGGAAGGAGCATAGGCTGGACTGCCAGCACTCATAGGAGGCTTCGTGTGTGCCCAGGACTGCGAGAATTAAATACAGGACACCCAGTTCAGTTTGAATTTCAGATAAACTATGAATAATGATTAGTGTAAGTATATCTCAATTTAACTGGAAAAAAAAAAAAAAAAAA</dnaseq> | <dnaseq>AGACCCGGCACCCGCGCAACGGAGGAGGGGCGCTGTGCCCTCTCCCCAACGGCGGTCAGCTTGGAACGCCTGCCCGGCGCACGCCCGGGGCCGGGGAGCCGAACTCGGTGCCAGCCGCACCCGGGCGGGTTGCTGGTGCGCCCTCCCCTCGCCCCCGTCCCTGGGGTCCTTGACCCAGGCTCTTGGGGCTAGCCTATCTTCTGAGGAGCACAAGGTCCCTGGGGGCTCAGGGAAGAGAAATTGGAGAAAGGGGGAGGAAGCCCCCAAGATGGATCACCCATTGCCTGGTTTCGCAGGAGACTGTCCGCCTTCAGTTCTCCAGCAGCTCGGGGATCATGGCCCACTGAACCCCCAAGCGCTTTCACCCGAACCCAAGGAGGACGACCAGGAAAGACGGGAACTCGCGTAGACACGCCCGGAAGCCCTTGTCATGTAAATAGCTGTCGGGGACTGGTGTATTGTCGCCGCCCCAGCCGGCGGGACCTGGGGCGAATCCACACCCATTGTCTGCTGCCCAAGGGGCCTCCGGCTGGGGGGCGCGGCTGCGGAGTTCAAAAGGGGTATGAGCAGGAGGGGTGTACTTTTAGTTCATTAAGTTTTAATTACAGGAGTGCTACAAGAACACATTCTTCAGGTTTAAAAAGATATTAAAATATTACATAAGAGACCTCCCCTCCCTGGCCCACCTCCAGCCTCTTAAAAATTTAGTGTGTCGCCTTTTAGACACTTTCTCAAAGCTTCACTTATTTAACAGGCACTTAAGGAGCACCTACCTGTGCCAGAAACTCTCCAAATATTAACTCAACCTGACACCGACTCAGTGTGGCCGAATATTACTCTCCCCATTTTACAGAGCGGGCAGCTGGTCAAGGAAGTCGCTTGTTGAAAGTCACACAGTGGTGGAGCCTGTGTGCCAACCCAGGACCCTGGGGAGCTGCCTCCCCCTCTCCCACGTAGTCCTGATTCTTTAAGTGTCCACATATTCCTGTAATGCCTGGAGTTTCAGTAATTAGCAGGGACTTAGTGTGTTCAGAGAAAAAAAAAGCTTTTAAAAATTATTGTTACTGTGTTTGTAACAGTTTGGATAGAGAAGGAAAAGCTGGAATTTGGGAAGTGAAGGTGGCCTCGGGGTAGAACTTACCTAGACCAGAGCGAATTCATCCTGAAGAACTCAGAGAAAGCCGGTGCAGGAAGTGGGTTCCCGCTCTCCCTGCACAGGCACAGTGATGCTGCCAGAGCTCTCCCAGAAAGACCAGGAGGCTTGTTCTGGAGAAGTCAAGCCCAGGGATGTGGCTCAGGCTGGTCCAAGCTCTTTGGAGGAGTCCAAGCGTGCCCAGCCCAGAGGGAGGTTCAGAGGCACTGACCGTCTTCTGTTTGGGAGGAGAAGCTCACTCTTGGAGCCACAGCCAGCACTAGGTCAGGACCCAGGCCCCGGCCCAGGAGTGGGGCAATACCCAGCGTCTACCCCAGATGGCACCCTGCTGTGAACTGGGCGCCCTCAGCCCCTGCCTTGAGGAAGGGGCAATACCACCAGCGTGTCTTTTATCAGGGAAGATATTGCTGCAGTTTGGCCGCTGCAACTTAAGAGAAAAGCTAAGGGGTCCCCCAGCATCCCTTGGGGTGCCACTGCAAATACTGGCTGGGCCTGGAGATGACCTGGGTCCCATTCACTTCCTAGGGTGAAGGAGGTCATCATTACCACCCCTGCTTTCAGCCATTTCTTCATTCATTCAATCAACAAACTGGCTGAGCTGCAACCCTGAGCCGGGGAATTCAGCCACTCCAGACACAGCCCCTGCCCTCCGGGAAGTCTCGGGAGACCTGGCTAGTCTGGCTGGGAGAAGTCACACGTTGATTGTCTTGGAAGTGAGATGGCATTTACACAATGGAGGCTGCACTGCCAGCAGGCAAAAATAACCAGTTAATTCAGTGGCTTAAAGAAACCAAACCTACCCACAACGCTTGACCTCCCATTGATCCATCTGCGACACCGGCAGTGGCTACCATTTATTGAGTGCTGATGGTGTCACCTGGGATTGACTTAGTGGTCTCTGGCGCTAGTTCCGAAGTTGATTCTGTCTGGAGAGCTTAATGCAGTGTTCAGACCTCAGGGTCCGAACCTGAGGGTCACCCAAAGATGAGTGGGACATAGCTGTGTGACCTCGGCTGAGTGCTTTCACCTCTCCAACCTCAGTTTCCTCTTCTGCAAAATGGGGTGGCTTCATGGCACCTTCACGTGGTGTGATTGCGAGGAATGAAGGGATCGATGCCTTGCAAGTAGAGGAGAAGGGGCCGGATACATCTTAGTTGTTATGTTATTTAATCATCTTGGCAACCCCGGGAGGGAGGAACCACTATCATTTTATTTTCCATTTTGCAGTTGAGGACAATGATGATTCCAGCACAGACAGGGCCCCTGACGGGGCAGTAGGAAAGGAGAATTGCTTTGGAAGGAGCATAGGCTGGACTGCCAGCACTCATAGGAGGCTTCGTGTGTGCCCAGGACTGCGAGAATTAAATACAGGACACCCAGTTCAGTTTGAATTTCAGATAAACTATGAATAATGATTAGTGTAAGTATATCTCAATTTAACTGGAAAAAAAAAAAAAAAAAA</dnaseq> | ||
| + | |||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | *Department of Burns and Plastic Surgery, The General Hospital of Jinan Military Command 25 Shifan Road, Jinan 250031, Shandong, P. R. China.<ref name="ref1" /> | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Bian D, Gao C, Bao K, Song G. The long non-coding RNA NKILA inhibits the | ||
| + | invasion-metastasis cascade of malignant melanoma via the regulation of NF-ĸB. Am | ||
| + | J Cancer Res. 2017 Jan 1;7(1):28-40. eCollection 2017. PubMed PMID: 28123845; | ||
| + | PubMed Central PMCID: PMC5250678. | ||
| + | </ref> | ||
| + | </references> | ||
Latest revision as of 06:56, 10 August 2019
Contents
Annotated Information
Approved Symbol
NKILA
Approved Name
NF-kappaB interacting long non-coding RNA
Disease
melanoma[1]
Chromosome
20q13.31
RefSeq ID
NR_131157
Ensembl ID
ENSG00000278709
Function
NKILA suppressed the development of malignant melanoma via the regulation of NF-ĸB and may be a potential therapeutic target in patients with melanoma.[1]
Sequence
>gi|768311636|ref|NR_131157.1| Homo sapiens NF-kappaB interacting long non-coding RNA (NKILA), long non-coding RNA
000001 AGACCCGGCA CCCGCGCAAC GGAGGAGGGG CGCTGTGCCC TCTCCCCAAC GGCGGTCAGC TTGGAACGCC TGCCCGGCGC 000080
000081 ACGCCCGGGG CCGGGGAGCC GAACTCGGTG CCAGCCGCAC CCGGGCGGGT TGCTGGTGCG CCCTCCCCTC GCCCCCGTCC 000160
000161 CTGGGGTCCT TGACCCAGGC TCTTGGGGCT AGCCTATCTT CTGAGGAGCA CAAGGTCCCT GGGGGCTCAG GGAAGAGAAA 000240
000241 TTGGAGAAAG GGGGAGGAAG CCCCCAAGAT GGATCACCCA TTGCCTGGTT TCGCAGGAGA CTGTCCGCCT TCAGTTCTCC 000320
000321 AGCAGCTCGG GGATCATGGC CCACTGAACC CCCAAGCGCT TTCACCCGAA CCCAAGGAGG ACGACCAGGA AAGACGGGAA 000400
000401 CTCGCGTAGA CACGCCCGGA AGCCCTTGTC ATGTAAATAG CTGTCGGGGA CTGGTGTATT GTCGCCGCCC CAGCCGGCGG 000480
000481 GACCTGGGGC GAATCCACAC CCATTGTCTG CTGCCCAAGG GGCCTCCGGC TGGGGGGCGC GGCTGCGGAG TTCAAAAGGG 000560
000561 GTATGAGCAG GAGGGGTGTA CTTTTAGTTC ATTAAGTTTT AATTACAGGA GTGCTACAAG AACACATTCT TCAGGTTTAA 000640
000641 AAAGATATTA AAATATTACA TAAGAGACCT CCCCTCCCTG GCCCACCTCC AGCCTCTTAA AAATTTAGTG TGTCGCCTTT 000720
000721 TAGACACTTT CTCAAAGCTT CACTTATTTA ACAGGCACTT AAGGAGCACC TACCTGTGCC AGAAACTCTC CAAATATTAA 000800
000801 CTCAACCTGA CACCGACTCA GTGTGGCCGA ATATTACTCT CCCCATTTTA CAGAGCGGGC AGCTGGTCAA GGAAGTCGCT 000880
000881 TGTTGAAAGT CACACAGTGG TGGAGCCTGT GTGCCAACCC AGGACCCTGG GGAGCTGCCT CCCCCTCTCC CACGTAGTCC 000960
000961 TGATTCTTTA AGTGTCCACA TATTCCTGTA ATGCCTGGAG TTTCAGTAAT TAGCAGGGAC TTAGTGTGTT CAGAGAAAAA 001040
001041 AAAAGCTTTT AAAAATTATT GTTACTGTGT TTGTAACAGT TTGGATAGAG AAGGAAAAGC TGGAATTTGG GAAGTGAAGG 001120
001121 TGGCCTCGGG GTAGAACTTA CCTAGACCAG AGCGAATTCA TCCTGAAGAA CTCAGAGAAA GCCGGTGCAG GAAGTGGGTT 001200
001201 CCCGCTCTCC CTGCACAGGC ACAGTGATGC TGCCAGAGCT CTCCCAGAAA GACCAGGAGG CTTGTTCTGG AGAAGTCAAG 001280
001281 CCCAGGGATG TGGCTCAGGC TGGTCCAAGC TCTTTGGAGG AGTCCAAGCG TGCCCAGCCC AGAGGGAGGT TCAGAGGCAC 001360
001361 TGACCGTCTT CTGTTTGGGA GGAGAAGCTC ACTCTTGGAG CCACAGCCAG CACTAGGTCA GGACCCAGGC CCCGGCCCAG 001440
001441 GAGTGGGGCA ATACCCAGCG TCTACCCCAG ATGGCACCCT GCTGTGAACT GGGCGCCCTC AGCCCCTGCC TTGAGGAAGG 001520
001521 GGCAATACCA CCAGCGTGTC TTTTATCAGG GAAGATATTG CTGCAGTTTG GCCGCTGCAA CTTAAGAGAA AAGCTAAGGG 001600
001601 GTCCCCCAGC ATCCCTTGGG GTGCCACTGC AAATACTGGC TGGGCCTGGA GATGACCTGG GTCCCATTCA CTTCCTAGGG 001680
001681 TGAAGGAGGT CATCATTACC ACCCCTGCTT TCAGCCATTT CTTCATTCAT TCAATCAACA AACTGGCTGA GCTGCAACCC 001760
001761 TGAGCCGGGG AATTCAGCCA CTCCAGACAC AGCCCCTGCC CTCCG
000081 ACGCCCGGGG CCGGGGAGCC GAACTCGGTG CCAGCCGCAC CCGGGCGGGT TGCTGGTGCG CCCTCCCCTC GCCCCCGTCC 000160
000161 CTGGGGTCCT TGACCCAGGC TCTTGGGGCT AGCCTATCTT CTGAGGAGCA CAAGGTCCCT GGGGGCTCAG GGAAGAGAAA 000240
000241 TTGGAGAAAG GGGGAGGAAG CCCCCAAGAT GGATCACCCA TTGCCTGGTT TCGCAGGAGA CTGTCCGCCT TCAGTTCTCC 000320
000321 AGCAGCTCGG GGATCATGGC CCACTGAACC CCCAAGCGCT TTCACCCGAA CCCAAGGAGG ACGACCAGGA AAGACGGGAA 000400
000401 CTCGCGTAGA CACGCCCGGA AGCCCTTGTC ATGTAAATAG CTGTCGGGGA CTGGTGTATT GTCGCCGCCC CAGCCGGCGG 000480
000481 GACCTGGGGC GAATCCACAC CCATTGTCTG CTGCCCAAGG GGCCTCCGGC TGGGGGGCGC GGCTGCGGAG TTCAAAAGGG 000560
000561 GTATGAGCAG GAGGGGTGTA CTTTTAGTTC ATTAAGTTTT AATTACAGGA GTGCTACAAG AACACATTCT TCAGGTTTAA 000640
000641 AAAGATATTA AAATATTACA TAAGAGACCT CCCCTCCCTG GCCCACCTCC AGCCTCTTAA AAATTTAGTG TGTCGCCTTT 000720
000721 TAGACACTTT CTCAAAGCTT CACTTATTTA ACAGGCACTT AAGGAGCACC TACCTGTGCC AGAAACTCTC CAAATATTAA 000800
000801 CTCAACCTGA CACCGACTCA GTGTGGCCGA ATATTACTCT CCCCATTTTA CAGAGCGGGC AGCTGGTCAA GGAAGTCGCT 000880
000881 TGTTGAAAGT CACACAGTGG TGGAGCCTGT GTGCCAACCC AGGACCCTGG GGAGCTGCCT CCCCCTCTCC CACGTAGTCC 000960
000961 TGATTCTTTA AGTGTCCACA TATTCCTGTA ATGCCTGGAG TTTCAGTAAT TAGCAGGGAC TTAGTGTGTT CAGAGAAAAA 001040
001041 AAAAGCTTTT AAAAATTATT GTTACTGTGT TTGTAACAGT TTGGATAGAG AAGGAAAAGC TGGAATTTGG GAAGTGAAGG 001120
001121 TGGCCTCGGG GTAGAACTTA CCTAGACCAG AGCGAATTCA TCCTGAAGAA CTCAGAGAAA GCCGGTGCAG GAAGTGGGTT 001200
001201 CCCGCTCTCC CTGCACAGGC ACAGTGATGC TGCCAGAGCT CTCCCAGAAA GACCAGGAGG CTTGTTCTGG AGAAGTCAAG 001280
001281 CCCAGGGATG TGGCTCAGGC TGGTCCAAGC TCTTTGGAGG AGTCCAAGCG TGCCCAGCCC AGAGGGAGGT TCAGAGGCAC 001360
001361 TGACCGTCTT CTGTTTGGGA GGAGAAGCTC ACTCTTGGAG CCACAGCCAG CACTAGGTCA GGACCCAGGC CCCGGCCCAG 001440
001441 GAGTGGGGCA ATACCCAGCG TCTACCCCAG ATGGCACCCT GCTGTGAACT GGGCGCCCTC AGCCCCTGCC TTGAGGAAGG 001520
001521 GGCAATACCA CCAGCGTGTC TTTTATCAGG GAAGATATTG CTGCAGTTTG GCCGCTGCAA CTTAAGAGAA AAGCTAAGGG 001600
001601 GTCCCCCAGC ATCCCTTGGG GTGCCACTGC AAATACTGGC TGGGCCTGGA GATGACCTGG GTCCCATTCA CTTCCTAGGG 001680
001681 TGAAGGAGGT CATCATTACC ACCCCTGCTT TCAGCCATTT CTTCATTCAT TCAATCAACA AACTGGCTGA GCTGCAACCC 001760
001761 TGAGCCGGGG AATTCAGCCA CTCCAGACAC AGCCCCTGCC CTCCG