Difference between revisions of "UMLILO"
Qianpeng Li (talk | contribs) (Created page with "''UMLILO'' is a prototypical immune gene–priming lncRNA. ==Annotated Information== ===Name=== Approved symbol: ''UMLILO'' Approved name: ''UMLILO'': upstream master lncRNA...") |
Qianpeng Li (talk | contribs) |
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===Evolution=== | ===Evolution=== | ||
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===Sequence=== | ===Sequence=== | ||
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AAACTAAACTAGATCTTAATTCTCACTGTAGAAAGTAAGTAGTCTTATAATATATTTGTA | AAACTAAACTAGATCTTAATTCTCACTGTAGAAAGTAAGTAGTCTTATAATATATTTGTA | ||
AAATTAACATTTTAATGTTTAATTAT</dnaseq> | AAATTAACATTTTAATGTTTAATTAT</dnaseq> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM. Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments. Nat Genet. 2019 Jan;51(1):138-150. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 01:44, 13 August 2019
UMLILO is a prototypical immune gene–priming lncRNA.
Contents
Annotated Information
Name
Approved symbol: UMLILO
Approved name: UMLILO: upstream master lncRNA of the inflammatory chemokine locus
HGNC ID: HGNC:51824
Ensembl ID: ENSG00000228277
Characteristics
UMLILO is a multi-exonic 575–base pair(bp) lncRNA and is transcribed from within the chemokine superenhancer[1].
Function
- UMLILO acts in cis to direct the WDR5–mixed lineage leukemia protein 1(MLL1) complex across the chemokine promoters (IL-8, CXCL1, CXCL2, and CXCL3) facilitating their H3K4me3 epigenetic priming[1].
- UMLILO is a cis-acting lncRNA, playing a key role in the expression of chemokine genes. UMLILO is central to the deposition of H3K4me3 on chemokine promoters during trained immune responses, and the deletion of UMLILO abrogates chemokine transcription[1].
Regulation
It is reported that β -glucan-mediated NFAT signaling increases immune gene–priming lncRNA transcription, including UMLILO[1].
Diseases
Expression
CAGE data showed that UMLILO is unidirectionally transcribed and expressed in innate immune/non-immune cells(monocytes, endothelium)[1].
Evolution
Sequence
>4 dna:chromosome chromosome:GRCh38:4:73709702:73715127:1
000001 TTTTGTGACC AGTGTCCTGA GCAATTGGCT TCATCTAGGC CTCAGATCAC AAAACAGAGT TGTATAAAAT GGAAAGTGCA 000080
000081 ATGCTTTTTT AGTAAAATAA CTTTTCTCTT CCTTCCTTTC TTGCTTTTTT CCTTCCTTCC TTCCTCCCTC CCTCCCTCTC 000160
000161 TTCCTTCCTT CCTTCCTTCT TTCCTTCCCC CACTTTTTTT TTGGCAGGGG GATAGAATGT AAGACTATAT ATATCAGATA 000240
000241 ATTCTCTGGG CTACATTTTA AAATTTTCAT CTGATAATTT ACTTTTGTTT CTGTGTGGTA GGAGTGAGAG CTCTCAATTA 000320
000321 TTTAGCACTA ATTGTGTGCC AGGTTCCATC TGAAGGCTTG ACAAGAGTCA CCTTAATTCT TTGCCATATT TTGAGGTAGA 000400
000401 TACTACTGGC ACCATTTTTT AGACTGAGAA AGGAGATGTA GAAAGGATAA GATGTTGTCC AAATCCACAT TGACAGTAAG 000480
000481 TTTTGGACAT GAGTCTTTAA TCTAGCAATA TCCGACTTTA GAGTGTGTTC TTAAGCACTA CTCTATAAGT TTTAAGCAGC 000560
000561 TCCTTTATGA TGTCATTGAA CCGGGTTTTC CAGTCACATT ATACATGTGG AGATTAAGAC CCATAATAAC AATGACAACA 000640
000641 CTTTCATAAC AGTTCATCTG TGTTAACATA CAAATTCTCG CAGCAACACT CCAGGTAAGT GCTCTTTTTA TCTCAGTTTT 000720
000721 ATGGATTAGT AACTGAATGC AGAGAGGTTA AGCAACTTGT CCAAGATCAC ATAGGAGTAG GTAGTAGAAT TGGGATTTAA 000800
000801 AGCCACACTC TTAACCACAA TTCTACTCTG TCCCTCTGAG TTATAAATTT AATTAGTATG ACATAAATAT ATGTGCAGCT 000880
000881 CTTTTAAAGA TTTACTGTGC ATATTTTTAA AATTGTTACA ACATAAGCAT TCTAGGCTTT TATTAGTCCT CCAACTTTAA 000960
000961 CATTTATGCT TTCATTTTTA TCTTGTAAAG TCTTAATTTA TAATAAAAAA TGGATGTGTA CTGTCCCATA TGTCTTCTTT 001040
001041 ATTTATTTAT TTATTTATTT ATTTGAGATG GATTCTCCCT CTGTTGCCCT GGCTGGAGTG CAGTGGTGCC ATCTTGGCTC 001120
001121 ACTACAACCT CTGCCTCCTG GGTTCAATCG ATTCTCCCAC CTCAGCCTCC CAAGTAGCTA GGATTACAGG CTCCCACCAC 001200
001201 CAGGCCCAGC TAATTTTTTT GTATTTTTGG TAGAGACAGG CTTTCACCAT ATTGGCCAGG TTGGTCTTGA ACTCCTGACC 001280
001281 TCATGTGATC CGCCTGCCTT GGCCTCCCAA AGTCCTGGGA TTACAGGTGT GAGCCACTGC ACTGGCCCCG TATAAAGAGG 001360
001361 AAGATTTTCC AAACACTGAT GAAACCTCTA ACAACATACT CTGCAGTTCA TAGATCGTTC CTACCTAGAA TTTAATTCGT 001440
001441 ATATGCATAC TGTTTCTTCA AAGCATTAAG AATGTGCAAA CAAGACTTCT TGGAAAAATG AGGCATATGG CATGCACAGT 001520
001521 CATGAGCTTC ATGGCAGGAG GGCAAGGGGA ACACTAAGTC ACTTGGGGCC ATGAGAAAGG AACTCTGGTC CTGTCCTGTC 001600
001601 CTTTCCCAGA GCAGGGATCC TAACACTTCT AAGAGAAGGG CCATTGGTAG CCTCTAGTTC TCAGAACTGT TTGTCCGCTA 001680
001681 ATGAAAATTA ACACACTTGA TTTTGGACAG GTTAATGTGA GATATCTATT ATTTCCCCAG TGAGATATCA TGTTGGCAGT 001760
001761 TGGATATATT CAAGTCTTGA GTCAGTTGAT ACCGACTAGA TAGATAGATA CATAAATACA TACATACATA GAAAATATTA 001840
001841 ACAGCAAAAT GATGCTGATG GCTCAGGATG TGTGTTGAGA CAGACAGAAC TGGGTTTTGT CATTCAAGCC GTTATTCACA 001920
001921 CCCAGTGTCA CCTAGGCCAA GGTTTGAGCT GCAATTACTT CAACTGTGAA ATGAGGTTTC CTTCAACAGA TATATATTGA 002000
002001 ATGCCTAGAA TGTTCCAAGC ACTGTTCTAG GTACTGCATA GAGCAGTGAA AAAAAAAAAA AACCTGACAA AATCTTCGCC 002080
002081 CTTCTTAAGT TTATATTCTA GTGTGTGTGT AGGAAGGAGG GGAACATGGA AAGTCAGGTA CTAAATTGGT GAAAAGGGAA 002160
002161 AATATATAGT ATGTCAGATG CTTACAAGTA TTAAAGAATA AAATAATGCA GAGAAGGTGA AAGGAAGTAT TTGCTGCAGG 002240
002241 AAGAGATGAG GAGCTGAAGA TGGTGAGAGT TAGAATTGTA AATAGGACAG TCAAAAAAAC CTTCACAGAG AAGCAAAAAT 002320
002321 TCTAAGGCAG GAGAGGGAGG GAGTCAGGTA GCTATCTGAG AGAAGACTGT TTCAGCAGAT GGAAACAGTC TTCAACAGAG 002400
002401 GAAAGAGCTA TTGCAAAGAC TCAACGCCTT GTGAGATAAA GGGAAAAAAA TCAATGTAGC TGAAACAGAC TGAATGGAAA 002480
002481 TCAAGAGGCC ATAGAAACCA CAGAGGGGTT GAAGATGTCA CTGCAGTTTT AGGCTGAGAG ACTGGAAAGA TGGAGCTACT 002560
002561 GATTACTGAA ATGGAAAACT CTTTGGGAGG AGTATATAAT TTTGGACAAG TTAAGTTTGA GATTTCTATT GCTGCCCAAG 002640
002641 CGAGTTGTCA AGGAGCCATT TGGATAGTCA TATCTGGAGT CAGCAAAGGA GACCAGGCTG TACATACACA TGTGCAAATT 002720
002721 GTCAGCTTTT GAGGATATTT ATAGCCACAA AAAGTGGGGA TAGGTAGAGA AGGAAAGAGG TCTCAGTTCC AAGGGATTGG 002800
002801 AGTTGGCTAC TGTTTAGAAA TCTAGGAGGA ACCAGCAACA GAATGACAGA GAAACCAGCA ACAGGGTGGT AGAGAAAATT 002880
002881 CAGGAATGTG TAGTATCCTG GAAGCCAAAG GAAGAGGAAG AGAAAGTAAG CTTCTACGTG AAATGTTGCA GATAAGCTAC 002960
002961 TTTCTTCACA GCATTACTGC ATGAGTTAAA TAAAATGCTA TTTGTACAAA ACAGCATAAT ATCTGGCACA GCACTGCAGG 003040
003041 TAAAGCTTGT TTTCATTTTC TACAATGAAG TTTTAAATGA ATATTTAAAA ATATATTTTG GACTTCTCAA AGCAAAATGT 003120
003121 AATCCCATTT ATAATTTCAT AAAGACATTT TATCTGCTAA TATCAGGACA TCATTTTCTC AAACACAATG AAACTTTTTA 003200
003201 AATGTGAGAA AATAAAATAC TTCTCAGAGG TATTTCATAA AAGCTTAAGA TAGACTCTTT TTGCCTCATA ACTTTTATGT 003280
003281 ATAATTTAAT AAAAGGTAGT AATGAGAAAA TCAGATCTAA TATATAGAAT TTTGTTTCAT AACCAAATTT TTAGAAATAA 003360
003361 GTCATCTTAT ATATTAAAGA ATAGCTAGAA GGAGAGAGGG ATGAATTTTA TGTATAAAAT TTATGTATAA TAATTTTTCC 003440
003441 TTATAAAATT TATGTATAAT TTTATAAAAG GTAATAATGA GAAAATCAGA TCTAATACAT AGAATTTTGT TGCATAATCA 003520
003521 AATTTTTAGA AATAAATTAT CTTATATATT AAAGGATAGC TAGAAGGAGA GAGGGATGAT GAAAGGAAAA GAACAAGACA 003600
003601 TTTTTCATGC TTACTCTGTG TGACACGCTC TGCAGGGCGC TTTATGTGTG GATCTTTTTT AGTCTGCATA TTAACCCTAC 003680
003681 AAGTTGGAAA TGGCTCCTCT CAAACACTGG AGATAGAGCA GCCCAAATGT ATCTGCTACT GTGGTGCCTT CCATGTGAGT 003760
003761 ATTTTCTCCA AATGCTAATT TGGAGAAAAC AATTTATATG AACGGAGACA CTATTACTTA TTTGCCCTCA AAAATGAAAG 003840
003841 TGACCCAAGG CTGGAGATAG GAATTTGTCC CAAACAATGT CTTCAGCCAC CCCTCCAAAC AAAGTTTGAA AGGGATGTGA 003920
003921 ATAAGTAAAT GCAGAATCAG AATTTTCTAT CTCTTCTGGC CTAAGTTCTT CATTTCTTAG TTGAAGATAA CCAAGGCCAA 004000
004001 ATCACGTAAT CAAATGACAG AAAATTATTC TGGAGACACA ACCAGGCATA TCAGATCTGT CTGTTTTTGG CTTGTGATGT 004080
004081 CCACACACAA CACCTGTGAA CAGGTGCACT CAGCCTACCA GGAAATGCAC TCATCATGTG TCATCTACAG ATTTTCTCAA 004160
004161 GACTAGAGCA TTTGTGAGAA ATGACCGTAA GGCTTTCCCT GTGGAGTTGA ATACAAAGAT TGAACATAGA CATTTTGAAT 004240
004241 AATCCTAGTG ACTTGCGGAT CCAGTTTCCA TAGAGCACTA GTTTCTCTAA GGCCACAGTC ACTAAATGAG GTTCCATGGC 004320
004321 AGGTGTAAAA TCTCACTGGG TGATTGTGTC ATGCTGTGCT TACAGCACTA TGTTGGGGGA GAAGAGAGGA AAACCTATTA 004400
004401 TTGAAATCTG TGCTATTTTA CATGACCTTT TAATTACTTA TTTTTAAAAC ATCTCTCCTT CTAGAATGCA AAACTCTCTG 004480
004481 AGGAGCTGAG AATATGTCTA CTGCTACCAA AATTGTAACC CCCATCATCT AGTAAAGAGT TGGTACACGG TGAACATTTG 004560
004561 CTGTGGGAAT GTATTCTGCT TCATTCCAGA GGCCTGCCAA TTCTTAATCT CACTATAGGC TGAAGAGCTG CTCACATAGA 004640
004641 ATACTTGTAG TGACTTCCAT TTTCACCAGT TTAGATCAGT GGACAGAGAG ATGCTGAATT ACTGCTCAAG AAGTATAGAT 004720
004721 CCACATGCCT TCAACTTCAG AATCTTAAAT TAGAGGCGAA TGTTGAGTCT ACTAAACTGT ATAGTCTGTA AAGGCAGGAA 004800
004801 CTGTATTTAT CTCAGTCATA TTTAATCCCA AGAGTCTTCA TAGTACCTGG CCCATATCCG TTGTTCAATA ATTGGTTTTT 004880
004881 TAAATACCTA ACTTATTAAA CAATGTGTTT GATTAAACAG CAGTGACAAA AAAGGGCTTA CTCAGTCTTA AGTGCTAGAA 004960
004961 GTAAAGACAG TCATGAGGGG CTTGCAATGA GCTCCACTGG GGGGAATTTT TCTTCTTCAC ATTTTTGTAC AATGAATGTC 005040
005041 ATCACAGGAC ACAGCAGATA CCCAAGAAAT ATTATTTTAA GGTATACTAT ACTCAAAGAA AACCAGGAAA GCCAAAAGAC 005120
005121 TCTTAATTAA TAGAAAACTG CTGAGTCAAT AGGATAGCTC ATATAAATAA ATTGTGTTCA GAATTTGATT TTCTAAATTA 005200
005201 AAAAAAATTA TGTAGTAATA TCTCGAGTAT AACAAATGTT TTAAGAATGG ATTTGTGAAA CTACGGCCAT TTAAATAATA 005280
005281 TCTTGAAATG TTCAAATATC AAATCTTTAT TGAATTATAT TCTACATAGT GATTAATCAA AAACTAAACT AGATCTTAAT 005360
005361 TCTCACTGTA GAAAGTAAGT AGTCTTATAA TATATTTGTA AAATTAACAT TTTAATGTTT AATTAT
000081 ATGCTTTTTT AGTAAAATAA CTTTTCTCTT CCTTCCTTTC TTGCTTTTTT CCTTCCTTCC TTCCTCCCTC CCTCCCTCTC 000160
000161 TTCCTTCCTT CCTTCCTTCT TTCCTTCCCC CACTTTTTTT TTGGCAGGGG GATAGAATGT AAGACTATAT ATATCAGATA 000240
000241 ATTCTCTGGG CTACATTTTA AAATTTTCAT CTGATAATTT ACTTTTGTTT CTGTGTGGTA GGAGTGAGAG CTCTCAATTA 000320
000321 TTTAGCACTA ATTGTGTGCC AGGTTCCATC TGAAGGCTTG ACAAGAGTCA CCTTAATTCT TTGCCATATT TTGAGGTAGA 000400
000401 TACTACTGGC ACCATTTTTT AGACTGAGAA AGGAGATGTA GAAAGGATAA GATGTTGTCC AAATCCACAT TGACAGTAAG 000480
000481 TTTTGGACAT GAGTCTTTAA TCTAGCAATA TCCGACTTTA GAGTGTGTTC TTAAGCACTA CTCTATAAGT TTTAAGCAGC 000560
000561 TCCTTTATGA TGTCATTGAA CCGGGTTTTC CAGTCACATT ATACATGTGG AGATTAAGAC CCATAATAAC AATGACAACA 000640
000641 CTTTCATAAC AGTTCATCTG TGTTAACATA CAAATTCTCG CAGCAACACT CCAGGTAAGT GCTCTTTTTA TCTCAGTTTT 000720
000721 ATGGATTAGT AACTGAATGC AGAGAGGTTA AGCAACTTGT CCAAGATCAC ATAGGAGTAG GTAGTAGAAT TGGGATTTAA 000800
000801 AGCCACACTC TTAACCACAA TTCTACTCTG TCCCTCTGAG TTATAAATTT AATTAGTATG ACATAAATAT ATGTGCAGCT 000880
000881 CTTTTAAAGA TTTACTGTGC ATATTTTTAA AATTGTTACA ACATAAGCAT TCTAGGCTTT TATTAGTCCT CCAACTTTAA 000960
000961 CATTTATGCT TTCATTTTTA TCTTGTAAAG TCTTAATTTA TAATAAAAAA TGGATGTGTA CTGTCCCATA TGTCTTCTTT 001040
001041 ATTTATTTAT TTATTTATTT ATTTGAGATG GATTCTCCCT CTGTTGCCCT GGCTGGAGTG CAGTGGTGCC ATCTTGGCTC 001120
001121 ACTACAACCT CTGCCTCCTG GGTTCAATCG ATTCTCCCAC CTCAGCCTCC CAAGTAGCTA GGATTACAGG CTCCCACCAC 001200
001201 CAGGCCCAGC TAATTTTTTT GTATTTTTGG TAGAGACAGG CTTTCACCAT ATTGGCCAGG TTGGTCTTGA ACTCCTGACC 001280
001281 TCATGTGATC CGCCTGCCTT GGCCTCCCAA AGTCCTGGGA TTACAGGTGT GAGCCACTGC ACTGGCCCCG TATAAAGAGG 001360
001361 AAGATTTTCC AAACACTGAT GAAACCTCTA ACAACATACT CTGCAGTTCA TAGATCGTTC CTACCTAGAA TTTAATTCGT 001440
001441 ATATGCATAC TGTTTCTTCA AAGCATTAAG AATGTGCAAA CAAGACTTCT TGGAAAAATG AGGCATATGG CATGCACAGT 001520
001521 CATGAGCTTC ATGGCAGGAG GGCAAGGGGA ACACTAAGTC ACTTGGGGCC ATGAGAAAGG AACTCTGGTC CTGTCCTGTC 001600
001601 CTTTCCCAGA GCAGGGATCC TAACACTTCT AAGAGAAGGG CCATTGGTAG CCTCTAGTTC TCAGAACTGT TTGTCCGCTA 001680
001681 ATGAAAATTA ACACACTTGA TTTTGGACAG GTTAATGTGA GATATCTATT ATTTCCCCAG TGAGATATCA TGTTGGCAGT 001760
001761 TGGATATATT CAAGTCTTGA GTCAGTTGAT ACCGACTAGA TAGATAGATA CATAAATACA TACATACATA GAAAATATTA 001840
001841 ACAGCAAAAT GATGCTGATG GCTCAGGATG TGTGTTGAGA CAGACAGAAC TGGGTTTTGT CATTCAAGCC GTTATTCACA 001920
001921 CCCAGTGTCA CCTAGGCCAA GGTTTGAGCT GCAATTACTT CAACTGTGAA ATGAGGTTTC CTTCAACAGA TATATATTGA 002000
002001 ATGCCTAGAA TGTTCCAAGC ACTGTTCTAG GTACTGCATA GAGCAGTGAA AAAAAAAAAA AACCTGACAA AATCTTCGCC 002080
002081 CTTCTTAAGT TTATATTCTA GTGTGTGTGT AGGAAGGAGG GGAACATGGA AAGTCAGGTA CTAAATTGGT GAAAAGGGAA 002160
002161 AATATATAGT ATGTCAGATG CTTACAAGTA TTAAAGAATA AAATAATGCA GAGAAGGTGA AAGGAAGTAT TTGCTGCAGG 002240
002241 AAGAGATGAG GAGCTGAAGA TGGTGAGAGT TAGAATTGTA AATAGGACAG TCAAAAAAAC CTTCACAGAG AAGCAAAAAT 002320
002321 TCTAAGGCAG GAGAGGGAGG GAGTCAGGTA GCTATCTGAG AGAAGACTGT TTCAGCAGAT GGAAACAGTC TTCAACAGAG 002400
002401 GAAAGAGCTA TTGCAAAGAC TCAACGCCTT GTGAGATAAA GGGAAAAAAA TCAATGTAGC TGAAACAGAC TGAATGGAAA 002480
002481 TCAAGAGGCC ATAGAAACCA CAGAGGGGTT GAAGATGTCA CTGCAGTTTT AGGCTGAGAG ACTGGAAAGA TGGAGCTACT 002560
002561 GATTACTGAA ATGGAAAACT CTTTGGGAGG AGTATATAAT TTTGGACAAG TTAAGTTTGA GATTTCTATT GCTGCCCAAG 002640
002641 CGAGTTGTCA AGGAGCCATT TGGATAGTCA TATCTGGAGT CAGCAAAGGA GACCAGGCTG TACATACACA TGTGCAAATT 002720
002721 GTCAGCTTTT GAGGATATTT ATAGCCACAA AAAGTGGGGA TAGGTAGAGA AGGAAAGAGG TCTCAGTTCC AAGGGATTGG 002800
002801 AGTTGGCTAC TGTTTAGAAA TCTAGGAGGA ACCAGCAACA GAATGACAGA GAAACCAGCA ACAGGGTGGT AGAGAAAATT 002880
002881 CAGGAATGTG TAGTATCCTG GAAGCCAAAG GAAGAGGAAG AGAAAGTAAG CTTCTACGTG AAATGTTGCA GATAAGCTAC 002960
002961 TTTCTTCACA GCATTACTGC ATGAGTTAAA TAAAATGCTA TTTGTACAAA ACAGCATAAT ATCTGGCACA GCACTGCAGG 003040
003041 TAAAGCTTGT TTTCATTTTC TACAATGAAG TTTTAAATGA ATATTTAAAA ATATATTTTG GACTTCTCAA AGCAAAATGT 003120
003121 AATCCCATTT ATAATTTCAT AAAGACATTT TATCTGCTAA TATCAGGACA TCATTTTCTC AAACACAATG AAACTTTTTA 003200
003201 AATGTGAGAA AATAAAATAC TTCTCAGAGG TATTTCATAA AAGCTTAAGA TAGACTCTTT TTGCCTCATA ACTTTTATGT 003280
003281 ATAATTTAAT AAAAGGTAGT AATGAGAAAA TCAGATCTAA TATATAGAAT TTTGTTTCAT AACCAAATTT TTAGAAATAA 003360
003361 GTCATCTTAT ATATTAAAGA ATAGCTAGAA GGAGAGAGGG ATGAATTTTA TGTATAAAAT TTATGTATAA TAATTTTTCC 003440
003441 TTATAAAATT TATGTATAAT TTTATAAAAG GTAATAATGA GAAAATCAGA TCTAATACAT AGAATTTTGT TGCATAATCA 003520
003521 AATTTTTAGA AATAAATTAT CTTATATATT AAAGGATAGC TAGAAGGAGA GAGGGATGAT GAAAGGAAAA GAACAAGACA 003600
003601 TTTTTCATGC TTACTCTGTG TGACACGCTC TGCAGGGCGC TTTATGTGTG GATCTTTTTT AGTCTGCATA TTAACCCTAC 003680
003681 AAGTTGGAAA TGGCTCCTCT CAAACACTGG AGATAGAGCA GCCCAAATGT ATCTGCTACT GTGGTGCCTT CCATGTGAGT 003760
003761 ATTTTCTCCA AATGCTAATT TGGAGAAAAC AATTTATATG AACGGAGACA CTATTACTTA TTTGCCCTCA AAAATGAAAG 003840
003841 TGACCCAAGG CTGGAGATAG GAATTTGTCC CAAACAATGT CTTCAGCCAC CCCTCCAAAC AAAGTTTGAA AGGGATGTGA 003920
003921 ATAAGTAAAT GCAGAATCAG AATTTTCTAT CTCTTCTGGC CTAAGTTCTT CATTTCTTAG TTGAAGATAA CCAAGGCCAA 004000
004001 ATCACGTAAT CAAATGACAG AAAATTATTC TGGAGACACA ACCAGGCATA TCAGATCTGT CTGTTTTTGG CTTGTGATGT 004080
004081 CCACACACAA CACCTGTGAA CAGGTGCACT CAGCCTACCA GGAAATGCAC TCATCATGTG TCATCTACAG ATTTTCTCAA 004160
004161 GACTAGAGCA TTTGTGAGAA ATGACCGTAA GGCTTTCCCT GTGGAGTTGA ATACAAAGAT TGAACATAGA CATTTTGAAT 004240
004241 AATCCTAGTG ACTTGCGGAT CCAGTTTCCA TAGAGCACTA GTTTCTCTAA GGCCACAGTC ACTAAATGAG GTTCCATGGC 004320
004321 AGGTGTAAAA TCTCACTGGG TGATTGTGTC ATGCTGTGCT TACAGCACTA TGTTGGGGGA GAAGAGAGGA AAACCTATTA 004400
004401 TTGAAATCTG TGCTATTTTA CATGACCTTT TAATTACTTA TTTTTAAAAC ATCTCTCCTT CTAGAATGCA AAACTCTCTG 004480
004481 AGGAGCTGAG AATATGTCTA CTGCTACCAA AATTGTAACC CCCATCATCT AGTAAAGAGT TGGTACACGG TGAACATTTG 004560
004561 CTGTGGGAAT GTATTCTGCT TCATTCCAGA GGCCTGCCAA TTCTTAATCT CACTATAGGC TGAAGAGCTG CTCACATAGA 004640
004641 ATACTTGTAG TGACTTCCAT TTTCACCAGT TTAGATCAGT GGACAGAGAG ATGCTGAATT ACTGCTCAAG AAGTATAGAT 004720
004721 CCACATGCCT TCAACTTCAG AATCTTAAAT TAGAGGCGAA TGTTGAGTCT ACTAAACTGT ATAGTCTGTA AAGGCAGGAA 004800
004801 CTGTATTTAT CTCAGTCATA TTTAATCCCA AGAGTCTTCA TAGTACCTGG CCCATATCCG TTGTTCAATA ATTGGTTTTT 004880
004881 TAAATACCTA ACTTATTAAA CAATGTGTTT GATTAAACAG CAGTGACAAA AAAGGGCTTA CTCAGTCTTA AGTGCTAGAA 004960
004961 GTAAAGACAG TCATGAGGGG CTTGCAATGA GCTCCACTGG GGGGAATTTT TCTTCTTCAC ATTTTTGTAC AATGAATGTC 005040
005041 ATCACAGGAC ACAGCAGATA CCCAAGAAAT ATTATTTTAA GGTATACTAT ACTCAAAGAA AACCAGGAAA GCCAAAAGAC 005120
005121 TCTTAATTAA TAGAAAACTG CTGAGTCAAT AGGATAGCTC ATATAAATAA ATTGTGTTCA GAATTTGATT TTCTAAATTA 005200
005201 AAAAAAATTA TGTAGTAATA TCTCGAGTAT AACAAATGTT TTAAGAATGG ATTTGTGAAA CTACGGCCAT TTAAATAATA 005280
005281 TCTTGAAATG TTCAAATATC AAATCTTTAT TGAATTATAT TCTACATAGT GATTAATCAA AAACTAAACT AGATCTTAAT 005360
005361 TCTCACTGTA GAAAGTAAGT AGTCTTATAA TATATTTGTA AAATTAACAT TTTAATGTTT AATTAT
Labs working on this lncRNA
- Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM. Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments. Nat Genet. 2019 Jan;51(1):138-150.
