Difference between revisions of "BRE-AS1"
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==Annotated Information== | ==Annotated Information== | ||
===Name=== | ===Name=== | ||
| − | + | Approved symbol：BABAM2-AS1 | |
| + | |||
| + | Approved name：BABAM2 antisense RNA 1 | ||
| + | |||
| + | HGNC ID：HGNC:44171 | ||
| + | |||
| + | Previous name：BRE antisense RNA 1 (non-protein coding)|BRE antisense RNA 1 | ||
| + | |||
| + | prev_symbol：BRE-AS1 | ||
| + | |||
| + | RefSeq ID：NR_028308 | ||
===Characteristics=== | ===Characteristics=== | ||
| − | BRE-AS1 is a noncoding RNA gene antisense to the BRE (brain and reproductive organ-expressed) gene | + | ''BRE-AS1'' is a noncoding RNA gene antisense to the BRE (brain and reproductive organ-expressed) gene <ref name="ref1" />. |
===Regulation=== | ===Regulation=== | ||
[[File:BRE-as1.JPG|right|thumb|400px|'''BRE-AS1 Regulation by Conserved Ca2+-Signaling Pathway''' <ref name="ref1" />.]] | [[File:BRE-as1.JPG|right|thumb|400px|'''BRE-AS1 Regulation by Conserved Ca2+-Signaling Pathway''' <ref name="ref1" />.]] | ||
| − | The | + | The promoter of human BRE-AS1 is regulated by the conserved Ca2+-signaling pathway that activates nuclear Ca2+/calmodulin kinases in neurons <ref name="ref1" />. |
===Expression=== | ===Expression=== | ||
| − | BRE-AS1 RNA | + | ''BRE-AS1'' RNA level is strongly (≥15-fold) upregulated in hiPSCd neurons with RNA-seq after 1 hr of Bic/4AP treatment <ref name="ref1" />. |
| + | |||
| + | ===Evolution=== | ||
| + | ''BRE-AS1'' has no ortholog in mouse <ref name="ref1" />. | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | *Department of Neurobiology, Interdisciplinary Center for Neurosciences (IZN), Heidelberg University, INF 364, 69120 Heidelberg, Germany. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Pruunsild P, Bengtson CP, Bading H. Networks of Cultured iPSC-Derived Neurons | ||
| + | Reveal the Human Synaptic Activity-Regulated Adaptive Gene Program. Cell Rep. | ||
| + | 2017 Jan 3;18(1):122-135 | ||
| + | </ref> | ||
| + | </references> | ||
| + | |||
===Sequence=== | ===Sequence=== | ||
>NR_028308.1 Homo sapiens BRE antisense RNA 1 (BRE-AS1), long non-coding RNA | >NR_028308.1 Homo sapiens BRE antisense RNA 1 (BRE-AS1), long non-coding RNA | ||
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AGTAAGATTGAGTAGACAGATCCTTCTGATTTTTCTTTTTTTTAAATTAAGGTAGCTTTTCTGATTACAA | AGTAAGATTGAGTAGACAGATCCTTCTGATTTTTCTTTTTTTTAAATTAAGGTAGCTTTTCTGATTACAA | ||
AAGTAATGTATGTTCACTGTAAAATTAGTAATAAATTCAGATATTCCAAAAAAAAAA</dnaseq> | AAGTAATGTATGTTCACTGTAAAATTAGTAATAAATTCAGATATTCCAAAAAAAAAA</dnaseq> | ||
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Latest revision as of 11:47, 20 November 2020
Contents
Annotated Information
Name
Approved symbol：BABAM2-AS1
Approved name：BABAM2 antisense RNA 1
HGNC ID：HGNC:44171
Previous name：BRE antisense RNA 1 (non-protein coding)|BRE antisense RNA 1
prev_symbol：BRE-AS1
RefSeq ID：NR_028308
Characteristics
BRE-AS1 is a noncoding RNA gene antisense to the BRE (brain and reproductive organ-expressed) gene [1].
Regulation
BRE-AS1 Regulation by Conserved Ca2+-Signaling Pathway [1].
The promoter of human BRE-AS1 is regulated by the conserved Ca2+-signaling pathway that activates nuclear Ca2+/calmodulin kinases in neurons [1].
Expression
BRE-AS1 RNA level is strongly (≥15-fold) upregulated in hiPSCd neurons with RNA-seq after 1 hr of Bic/4AP treatment [1].
Evolution
BRE-AS1 has no ortholog in mouse [1].
Labs working on this lncRNA
- Department of Neurobiology, Interdisciplinary Center for Neurosciences (IZN), Heidelberg University, INF 364, 69120 Heidelberg, Germany.
References
Sequence
>NR_028308.1 Homo sapiens BRE antisense RNA 1 (BRE-AS1), long non-coding RNA
000001 GTATGATTCC CCTCATCAGG CAACAAGGAA CTAATACTCG GGGTTTACAG GAACCAGGGG ATGGGCCAGA TATGGAGAAA 000080
000081 GAGACGCCTC TGGCCTTGGG GGCTCGTTCT TGAGGGAATC AGCGTGATGG GGATGAGAAG GGCATCTTTG GAACGGGGGC 000160
000161 CTTCTCCATA GGAAGAGGAG GCGAGTCCCC TGGCCATATT TAAACCACAG TTCTCCACGC CACCTGTGCG ACTCGGGATC 000240
000241 CAACCTCCCC GCACCAGCCC CAGTCCAGGT ACCTGGAACT TAGTCCGATC GGTAACCGGC GACTACGTGG GGTACAGGTA 000320
000321 CCCGAGCGCG CCCCCGACAG ACGCACCGAC CTGCGCGCGC GCCGCGGGCA GGATGCGTGC GCACTCCCCG GACGTCCCGC 000400
000401 CCCGCCCCCT CTGCGGCCCC GAAGCTGGGC GGCGTGCGCG CCCCCGCGCC GCGCCGAGCC GGGCGCTCGG AAAGGCGTCC 000480
000481 CCGCGGTGCC TGACAGTTCC TTCCTCAGCG CCTGCCCCGT GAGTGACGAG GAGCGCGGAG TCTCGCCATA TCAGGAGGGC 000560
000561 CCTGTTACGT GAGGCTGTGC ACCGAGACTA TTCCAGGAAG AAGAGGGGAC ACTTGGTGGG CGGGGTGATT TCGGGCAGTC 000640
000641 AGGTGGGCGA CCCGCGTAGG CGTCTGAAAG GCCCGCGTCG TTAGGGAGGG CAGGAGTGGC GTCTCTGGTT ACGGGGTCGG 000720
000721 GCAAAGGGCA GAGGTCACCG TCCAGGTTGG ACAGCAGCAC CTTTGAGCGA TGGCGGCGTC TGGGGAACCC CAGAGGCAGT 000800
000801 GGCAAGAGGA GGTGGCGGCG GTGGTAGTGG TGGGCTCCTG CATGACCGAC CTGGTCAGGT TAGTCCGGGG CCAGTTACTC 000880
000881 AGTCTGCGGC TCGGGGGAGG AGGCGTGCCG TGCGCTATGC GCCCAGTGGA GCTTTTGGGC GCTGGGTCTC CAGGGATAGA 000960
000961 CAGTGCTAGC TTTGGGTATG AGCTGCAGGT TTTCGAAGCC TTCAGCCTAC CTTCCTGGCA TGAAAGAACT TGAGTATATA 001040
001041 AAGGTAAATC TCAGGGGAGG GGACGTAATA GGCCAGGGTT TAGTGAAAGC TCTAATATTA CTCAAAGCGC TCCCCAAAGA 001120
001121 CCTGCCCTCC AAAGACTTGC GCCCCCAAAG ACCTTTCTTG GCCCGGCTGC TGAGCCTTTC CCCAAACGAG CCAGGGAACT 001200
001201 TTGCCCACGT CATTTTACCT CCGAGAATGT GCCTACCTCA CAGGGTTGTT GTGAGGACTA AATGAAGTAA AGTGTTTTGT 001280
001281 CAAGCGTAAC ATTATCCAAA TTGGGTATTA TTCGTCTGAG CTTATTGTAT AAAATAATGA GTTGAGCAGA AATCAAAAAG 001360
001361 ACTGTCACCT TTCACCATGT TGATTGTCGG CATTACTGCA GTATTTTATA TTTACAGCGT ATTTTTCAGC AAGCCAAGTA 001440
001441 TGAATCAAAA TAAAAACATA AACACAGTAT TTACAACCTC TGAAAACGAT GATCAAATTA TGATAGAAAA TATGCCAAAT 001520
001521 GAAAATTGTT GAGTTAGGTC AGTAAGATTG AGTAGACAGA TCCTTCTGAT TTTTCTTTTT TTTAAATTAA GGTAGCTTTT 001600
001601 CTGATTACAA AAGTAATGTA TGTTCACTGT AAAATTAGTA ATAAATTCAG ATATTCCAAA AAAAAAA
000081 GAGACGCCTC TGGCCTTGGG GGCTCGTTCT TGAGGGAATC AGCGTGATGG GGATGAGAAG GGCATCTTTG GAACGGGGGC 000160
000161 CTTCTCCATA GGAAGAGGAG GCGAGTCCCC TGGCCATATT TAAACCACAG TTCTCCACGC CACCTGTGCG ACTCGGGATC 000240
000241 CAACCTCCCC GCACCAGCCC CAGTCCAGGT ACCTGGAACT TAGTCCGATC GGTAACCGGC GACTACGTGG GGTACAGGTA 000320
000321 CCCGAGCGCG CCCCCGACAG ACGCACCGAC CTGCGCGCGC GCCGCGGGCA GGATGCGTGC GCACTCCCCG GACGTCCCGC 000400
000401 CCCGCCCCCT CTGCGGCCCC GAAGCTGGGC GGCGTGCGCG CCCCCGCGCC GCGCCGAGCC GGGCGCTCGG AAAGGCGTCC 000480
000481 CCGCGGTGCC TGACAGTTCC TTCCTCAGCG CCTGCCCCGT GAGTGACGAG GAGCGCGGAG TCTCGCCATA TCAGGAGGGC 000560
000561 CCTGTTACGT GAGGCTGTGC ACCGAGACTA TTCCAGGAAG AAGAGGGGAC ACTTGGTGGG CGGGGTGATT TCGGGCAGTC 000640
000641 AGGTGGGCGA CCCGCGTAGG CGTCTGAAAG GCCCGCGTCG TTAGGGAGGG CAGGAGTGGC GTCTCTGGTT ACGGGGTCGG 000720
000721 GCAAAGGGCA GAGGTCACCG TCCAGGTTGG ACAGCAGCAC CTTTGAGCGA TGGCGGCGTC TGGGGAACCC CAGAGGCAGT 000800
000801 GGCAAGAGGA GGTGGCGGCG GTGGTAGTGG TGGGCTCCTG CATGACCGAC CTGGTCAGGT TAGTCCGGGG CCAGTTACTC 000880
000881 AGTCTGCGGC TCGGGGGAGG AGGCGTGCCG TGCGCTATGC GCCCAGTGGA GCTTTTGGGC GCTGGGTCTC CAGGGATAGA 000960
000961 CAGTGCTAGC TTTGGGTATG AGCTGCAGGT TTTCGAAGCC TTCAGCCTAC CTTCCTGGCA TGAAAGAACT TGAGTATATA 001040
001041 AAGGTAAATC TCAGGGGAGG GGACGTAATA GGCCAGGGTT TAGTGAAAGC TCTAATATTA CTCAAAGCGC TCCCCAAAGA 001120
001121 CCTGCCCTCC AAAGACTTGC GCCCCCAAAG ACCTTTCTTG GCCCGGCTGC TGAGCCTTTC CCCAAACGAG CCAGGGAACT 001200
001201 TTGCCCACGT CATTTTACCT CCGAGAATGT GCCTACCTCA CAGGGTTGTT GTGAGGACTA AATGAAGTAA AGTGTTTTGT 001280
001281 CAAGCGTAAC ATTATCCAAA TTGGGTATTA TTCGTCTGAG CTTATTGTAT AAAATAATGA GTTGAGCAGA AATCAAAAAG 001360
001361 ACTGTCACCT TTCACCATGT TGATTGTCGG CATTACTGCA GTATTTTATA TTTACAGCGT ATTTTTCAGC AAGCCAAGTA 001440
001441 TGAATCAAAA TAAAAACATA AACACAGTAT TTACAACCTC TGAAAACGAT GATCAAATTA TGATAGAAAA TATGCCAAAT 001520
001521 GAAAATTGTT GAGTTAGGTC AGTAAGATTG AGTAGACAGA TCCTTCTGAT TTTTCTTTTT TTTAAATTAA GGTAGCTTTT 001600
001601 CTGATTACAA AAGTAATGTA TGTTCACTGT AAAATTAGTA ATAAATTCAG ATATTCCAAA AAAAAAA