Difference between revisions of "BCL6-AS1"
(Created page with " ==Annotated Information== ===Name=== BCL6-AS1 ===Alias=== BCL6 antisense RNA 1;lnc-RP11-211G3.3.1-1 ===Expression=== Expression of BCL6-AS1 was detected in the germinal cell...") |
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| − | + | BCL6 translocations occur at distinct sequence motifs within intron 1 of the BCL6 gene that are recognized and deaminated by activation-induced cytidine deaminase (AID). | |
==Annotated Information== | ==Annotated Information== | ||
===Name=== | ===Name=== | ||
| − | BCL6-AS1 | + | Approved symbol:BCL6-AS1 |
| − | + | ||
| − | BCL6 antisense RNA 1 | + | Approved name:BCL6 antisense RNA 1 |
| + | |||
| + | HGNC ID:HGNC:51843 | ||
| + | |||
| + | Previous name:BCL6 antisense 1 | ||
| + | |||
| + | Alias symbol:lnc-RP11-211G3.3.1-1 | ||
===Expression=== | ===Expression=== | ||
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<references> | <references> | ||
<ref name="ref1"> | <ref name="ref1"> | ||
| − | Lu Z, Pannunzio NR, Greisman HA, Casero D, Parekh C, Lieber MR. Convergent | + | Lu Z, Pannunzio NR, Greisman HA, Casero D, Parekh C, Lieber MR. Convergent BCL6 and lncRNA promoters demarcate the major breakpoint region for BCL6 |
| − | BCL6 and lncRNA promoters demarcate the major breakpoint region for BCL6 | + | translocations. Blood. 2015 Oct 1;126(14):1730-1. doi:10.1182/blood-2015-07-657999. Epub 2015 Aug 14. |
| − | translocations. Blood. 2015 Oct 1;126(14):1730-1. doi: | ||
| − | 10.1182/blood-2015-07-657999. Epub 2015 Aug 14 | ||
| − | |||
</ref> | </ref> | ||
</references> | </references> | ||
Latest revision as of 06:08, 25 November 2020
BCL6 translocations occur at distinct sequence motifs within intron 1 of the BCL6 gene that are recognized and deaminated by activation-induced cytidine deaminase (AID).
Contents
Annotated Information
Name
Approved symbol:BCL6-AS1
Approved name:BCL6 antisense RNA 1
HGNC ID:HGNC:51843
Previous name:BCL6 antisense 1
Alias symbol:lnc-RP11-211G3.3.1-1
Expression
Expression of BCL6-AS1 was detected in the germinal cell B-cell type of DLBCL and at a lower level in the activated B-cell type of diffuse large B-cell lymphoma (DLBCL)[1]
Diseases
diffuse large B-cell lymphoma[1]
Labs working on this lncRNA
- University of Southern California Norris Comprehensive Cancer Center, Departments of Pathology, Biochemistry & Molecular Biology, Molecular Microbiology & Immunology, and Biological Sciences (Section of Molecular and Computational Biology), University of Southern California Keck School of Medicine, Los Angeles, CA.
