Difference between revisions of "SFTA1P"

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SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .<ref name="ref1" />
 
SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .<ref name="ref1" />
 
===Expression===  
 
===Expression===  
[[File:SFTA1P.jpeg|thumb|300px|SFTA1P expression is down-regulated in NSCLC tissues <ref name="ref2"/>]]           
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[[File:SFTA1P.gif|thumb|300px|SFTA1P expression is down-regulated in NSCLC tissues <ref name="ref2"/>]]           
SFTA1P is down-regulated in LUAD tissues.<ref name="ref2" />  
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SFTA1P is down-regulated in LUAD tissues.<ref name="ref2" />
  
 
===Diseases===       
 
===Diseases===       

Latest revision as of 12:12, 19 February 2021

SFTA1P ,a pseudogene-derived long noncoding RNA,SFTA1P ,a pseudogene-derived long noncoding RNA,exerts the tumor suppressor functions in human lung adenocarcinoma. [1]

Annotated Information

Name

Approved symbol:SFTA1P

Approved name:surfactant associated 1, lncRNA

HGNC ID:18383

Previous name:surfactant associated protein F|surfactant associated 1, pseudogene

RefSeq ID:NR_027082

Prev_symbol:SFTPF

Characteristics

located in 10p14 and 693 nt inlength.[1]

Function

SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .[2]

Expression

SFTA1P expression is down-regulated in NSCLC tissues [1]

SFTA1P is down-regulated in LUAD tissues.[1]

Diseases

Lung squamous cell carcinoma(LSCC) [2]

Labs working on this lncRNA

  • Department of Intensive Care Unit , Renmin Hospital, Hubei University of Medicine , Shiyan , Hubei , P.R. China.[2]
  • Department of Cardiology , The Fifth People's Hospital of Shanghai, Fudan University , Shanghai , China.[2]
  • Department of Thoracic Surgery , The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an , Huai'an , China.[2]
  • Department of Thoracic Surgery , Huai'an First People's Hospital, Nanjing Medical University , Huai'an, Jiangsu , China.[2]
  • Department of Joint Trauma, Junan County People's Hospital, Linyi, People's Republic of China.The[1]
  • Department of Respiratory Medicine, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, People's Republic of China.The[1]
  • Department of Clinical Laboratory, Nanjing Chest Hospital, Nanjing, People's Republic of China.The[1]
  • Department of Oncology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, People's Republic of China.The[1]
  • Department of Respiratory Medicine, Huzhou Central Hospital, Huzhou, People's Republic of China.The[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Zhang H, Xiong Y, Xia R, Wei C, Shi X, Nie F. The pseudogene-derived long noncoding RNA SFTA1P is down-regulated and suppresses cell migration and invasion in lung adenocarcinoma. Tumour Biol. 2017 Feb;39(2):1010428317691418. doi: 10.1177/1010428317691418.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Huang GQ, Ke ZP, Hu HB, Gu B. Co-expression network analysis of long noncoding RNAs (IncRNAs) and cancer genes revealsSFTA1P and CASC2abnormalities in lung squamous cell carcinoma. Cancer Biol Ther. 2017 Feb;18(2):115-122. doi: 10.1080/15384047.2017.1281494.