Difference between revisions of "SFTA1P"
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SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .<ref name="ref1" /> | SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .<ref name="ref1" /> | ||
===Expression=== | ===Expression=== | ||
− | [[File:SFTA1P. | + | [[File:SFTA1P.gif|thumb|300px|SFTA1P expression is down-regulated in NSCLC tissues <ref name="ref2"/>]] |
− | SFTA1P is down-regulated in LUAD tissues.<ref name="ref2" /> | + | SFTA1P is down-regulated in LUAD tissues.<ref name="ref2" /> |
===Diseases=== | ===Diseases=== |
Latest revision as of 12:12, 19 February 2021
SFTA1P ,a pseudogene-derived long noncoding RNA,SFTA1P ,a pseudogene-derived long noncoding RNA,exerts the tumor suppressor functions in human lung adenocarcinoma. [1]
Contents
Annotated Information
Name
Approved symbol:SFTA1P
Approved name:surfactant associated 1, lncRNA
HGNC ID:18383
Previous name:surfactant associated protein F|surfactant associated 1, pseudogene
RefSeq ID:NR_027082
Prev_symbol:SFTPF
Characteristics
located in 10p14 and 693 nt inlength.[1]
Function
SFTA1P and CASC2 played important role in the regulation of both oncogene and TSGs during the carcinogenesis of LSCC .[2]
Expression
SFTA1P is down-regulated in LUAD tissues.[1]
Diseases
Lung squamous cell carcinoma(LSCC) [2]
Labs working on this lncRNA
- Department of Intensive Care Unit , Renmin Hospital, Hubei University of Medicine , Shiyan , Hubei , P.R. China.[2]
- Department of Cardiology , The Fifth People's Hospital of Shanghai, Fudan University , Shanghai , China.[2]
- Department of Thoracic Surgery , The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an , Huai'an , China.[2]
- Department of Thoracic Surgery , Huai'an First People's Hospital, Nanjing Medical University , Huai'an, Jiangsu , China.[2]
- Department of Joint Trauma, Junan County People's Hospital, Linyi, People's Republic of China.The[1]
- Department of Respiratory Medicine, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, People's Republic of China.The[1]
- Department of Clinical Laboratory, Nanjing Chest Hospital, Nanjing, People's Republic of China.The[1]
- Department of Oncology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, People's Republic of China.The[1]
- Department of Respiratory Medicine, Huzhou Central Hospital, Huzhou, People's Republic of China.The[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Zhang H, Xiong Y, Xia R, Wei C, Shi X, Nie F. The pseudogene-derived long noncoding RNA SFTA1P is down-regulated and suppresses cell migration and invasion in lung adenocarcinoma. Tumour Biol. 2017 Feb;39(2):1010428317691418. doi: 10.1177/1010428317691418.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Huang GQ, Ke ZP, Hu HB, Gu B. Co-expression network analysis of long noncoding RNAs (IncRNAs) and cancer genes revealsSFTA1P and CASC2abnormalities in lung squamous cell carcinoma. Cancer Biol Ther. 2017 Feb;18(2):115-122. doi: 10.1080/15384047.2017.1281494.