Difference between revisions of "Lnc-NDST1-1:2"
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Section Description | Section Description | ||
| − | ID | + | ID Alpha 250/ Alpha 280 |
Characteristics Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin. | Characteristics Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin. | ||
Expression Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus. | Expression Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus. | ||
Revision as of 12:19, 6 October 2014
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Contents
Annotated Information
Transcriptomic Nomeclature
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Function
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Regulation
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Expression
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Allelic Information and Variation
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Evolution
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Labs working on this lncRNA
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References
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Basic Information
| Transcript ID |
lnc-NDST1-1:2 |
| Source |
LNCipedia2.1 |
| Same with |
, |
| Classification |
antisense |
| Length |
256 nt |
| Genomic location |
chr5+:149829002..149829258 |
| Exon number |
1 |
| Exons |
149829002..149829258 |
| Genome context |
|
| Sequence |
000001 GCCGTATTGC GGGGCCGAGG CCTTAAAAGG CTGGACCCGC ACTCACCCTT ACTTCACAAG CTCCTCCCTG AAAGCAAAAC 000080
000081 GGGCCTTCTG AGACCAGGAA CGAACTCAAT CCCGAGTTGG CCAGGATCCA GGTGGGCCAG CCGCGCGTCT CTTGCCCGGC 000160 000161 ACCTAGCTCG GTTCCCACGG AAAGACCCCC GTCTCTCGTC CCAAGCCCCA CAGGGTCCCC TCGCCGCAGG ATGCCCCCCG 000240 000241 ATTGTCGCGC CCGGGC |
Annotation (From lncRNAdb)
| Section | Description |
|---|---|
| ID | Alpha 250/ Alpha 280 |
| Characteristics | Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin. |
| Expression | Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus. |
| Function | Regulates RPS14 transcription.. Each lncRNA can interact with the Rps14 gene loci to stimulate its expression in-trans.. Each lncRNA is transcribed through a known enhancer with putative transcription factor binding abilities, suggesting the 'enhancer' may be the transcribed RNA, which could be recruiting transcription factors to the Rps14 gene. |
