Difference between revisions of "NONHSAT113225"
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==Annotated Information== | ==Annotated Information== | ||
+ | ===Name=== | ||
+ | KRASP1: KRAS Pseudogene 1 | ||
+ | |||
+ | ===Characteristics=== | ||
+ | Processed pseudogene of KRAS oncogene on 6p12-p11 [http://www.ncbi.nlm.nih.gov/pubmed/6308466 (McGrath (1983))]. | ||
+ | |||
+ | ===Function=== | ||
+ | Probable competing endogenous RNA (ceRNA). KRASP1 is hypothesised to act as a decoy for miRNAs targeting KRAS, similar to how PTENP1 acts a decoy for PTEN [http://www.ncbi.nlm.nih.gov/pubmed/20577206 (Poliseno (2010))]. Expression of the KRASP1 3'UTR sequence lead to de-repression of KRAS mRNA levels and increased cellular proliferation [http://www.ncbi.nlm.nih.gov/pubmed/20577206 (Poliseno (2010))]. | ||
+ | |||
+ | ===Expression=== | ||
+ | Please input expression information here. | ||
+ | |||
+ | ===Conservation=== | ||
+ | Pseudogene sequence at this locus only present in some primates. | ||
+ | |||
+ | ===Misc=== | ||
+ | Please input misc information here. | ||
+ | |||
===Transcriptomic Nomeclature=== | ===Transcriptomic Nomeclature=== | ||
Please input transcriptomic nomeclature information here. | Please input transcriptomic nomeclature information here. | ||
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===Regulation=== | ===Regulation=== | ||
Please input regulation information here. | Please input regulation information here. | ||
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===Allelic Information and Variation=== | ===Allelic Information and Variation=== | ||
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}} | }} | ||
[[Category:Intergenic]] | [[Category:Intergenic]] | ||
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Revision as of 02:37, 10 October 2014
Please input one-sentence summary here.
Contents
Annotated Information
Name
KRASP1: KRAS Pseudogene 1
Characteristics
Processed pseudogene of KRAS oncogene on 6p12-p11 (McGrath (1983)).
Function
Probable competing endogenous RNA (ceRNA). KRASP1 is hypothesised to act as a decoy for miRNAs targeting KRAS, similar to how PTENP1 acts a decoy for PTEN (Poliseno (2010)). Expression of the KRASP1 3'UTR sequence lead to de-repression of KRAS mRNA levels and increased cellular proliferation (Poliseno (2010)).
Expression
Please input expression information here.
Conservation
Pseudogene sequence at this locus only present in some primates.
Misc
Please input misc information here.
Transcriptomic Nomeclature
Please input transcriptomic nomeclature information here.
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
Please input related labs here.
References
Please input cited references here.
Basic Information
Transcript ID |
NONHSAT113225 |
Source |
NONCODE4.0 |
Same with |
, |
Classification |
intergenic |
Length |
865 nt |
Genomic location |
chr6+:54635169..54636037 |
Exon number |
2 |
Exons |
54635169..54635601,54635608..54636037 |
Genome context |
|
Sequence |
000001 CTGCATCATA AATTCCTAAG GAATGGAATG AGCTTTGACT GCCTTACCTT GAGAATAAGC ATATTCACGT AAAGTATATA 000080
000081 AGACAAATAC TGGTTTAGAT GAAGCTCGGC CAGTACTCCC GGCCTCCGCC ATTTCGGACT GGGAGCTCCG TGGCGCAGGC 000160 000161 ACTGAAGGCG GCGGCAGGGC CAGAGGCTCA GCGGCTCCCA GACCTGCTGA AAATGACTGA ATATAAACTT GGCGGTAGTT 000240 000241 GGAGCTGGTA GCGTAAGCAA AAGTGTCTTG ACGATACAGC TAATTCAGAA TCATTTTGTG GACCAATATG ATCCAACAAT 000320 000321 AGAGAATTCC TACAGGAAGC AAGTAGTAAT TGATGGAGAA ACCTGTCTCT TGGATATTCT TGACACAACA GGTCAAGAAG 000400 000401 AGTACAATGC AATGAGGACC AGTACATGAG GACTGGGGGG GGGGGGGGCT TTCTTTGTGT ATTTGCCATA AATAATATTA 000480 000481 AATCATTTGA AGATATGCAC AATTATAGAA AACAAATTAA AAGATTTAAG GACTCTGAAG ATGTGCCTAT GGTCCTAGTA 000560 000561 GGAAATAAAT GTGATTTGCC TTCTAGAACA GTAGACACAA AAGGCTCAGG ACTTAGCAAG GAGTTAGGGA ATTCCCTTTA 000640 000641 TTGAAACCAG CAAAGACAGG GTGTTAATGA TGCCTTCTAT ACATTAGTTT GAGAAATAAA AGATGAGCAA AGATGGTAAG 000720 000721 AAGAAGAAAA GTCAATGACA AAGTGTGTAA TTATGTAAAT ACAATTAGTA CTTTTTTCTT AAGGCATAGC TTAAGTAAAA 000800 000801 CTGGTAATTT TTATACATTA CACTAAACTA TTAGCATTGT TTTAGCATTA CCTAATTTTT TTCCT |