Difference between revisions of "NONHSAT074775"
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==Annotated Information== | ==Annotated Information== | ||
| + | ===Name=== | ||
| + | Zeb2NAT: Zeb2 natural antisense transcript | ||
| + | |||
| + | ===Characteristics=== | ||
| + | >1.2 kb; antisense to Zeb2 (a transcriptional repressor of E-cadherin) [http://www.ncbi.nlm.nih.gov/pubmed/13679026 (Nelles (2003))]. | ||
| + | |||
| + | ===Function=== | ||
| + | Controls translation and therefore function of the Zeb2 protein coding gene through regulation of Zeb2 mRNA splicing [http://www.ncbi.nlm.nih.gov/pubmed/18347095 (Beltran (2008))]. Zeb2 translation requires retention of an intron, Zeb2NAT overlaps the 5' splicing site of this intron and when expressed inhibits splicing allowing translation of Zeb2 [http://www.ncbi.nlm.nih.gov/pubmed/18347095 (Beltran (2008))]. Snail1 acts to stimulate Zeb2 synthesis via post-transcriptional regulation which appears to be mediated by Zeb2NAT [http://www.ncbi.nlm.nih.gov/pubmed/18347095 (Beltran (2008))]. | ||
| + | |||
| + | ===Expression=== | ||
| + | Expression is upregulated by Snail1 [http://www.ncbi.nlm.nih.gov/pubmed/18347095 (Beltran (2008))]. | ||
| + | |||
| + | ===Conservation=== | ||
| + | Good conservation between human and mouse [http://www.ncbi.nlm.nih.gov/pubmed/13679026 (Nelles (2003))]. | ||
| + | |||
| + | ===Misc=== | ||
| + | Please input misc information here. | ||
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===Transcriptomic Nomeclature=== | ===Transcriptomic Nomeclature=== | ||
Please input transcriptomic nomeclature information here. | Please input transcriptomic nomeclature information here. | ||
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===Regulation=== | ===Regulation=== | ||
Please input regulation information here. | Please input regulation information here. | ||
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===Allelic Information and Variation=== | ===Allelic Information and Variation=== | ||
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}} | }} | ||
[[Category:Intergenic]] | [[Category:Intergenic]] | ||
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Revision as of 01:37, 11 October 2014
Please input one-sentence summary here.
Contents
Annotated Information
Name
Zeb2NAT: Zeb2 natural antisense transcript
Characteristics
>1.2 kb; antisense to Zeb2 (a transcriptional repressor of E-cadherin) (Nelles (2003)).
Function
Controls translation and therefore function of the Zeb2 protein coding gene through regulation of Zeb2 mRNA splicing (Beltran (2008)). Zeb2 translation requires retention of an intron, Zeb2NAT overlaps the 5' splicing site of this intron and when expressed inhibits splicing allowing translation of Zeb2 (Beltran (2008)). Snail1 acts to stimulate Zeb2 synthesis via post-transcriptional regulation which appears to be mediated by Zeb2NAT (Beltran (2008)).
Expression
Expression is upregulated by Snail1 (Beltran (2008)).
Conservation
Good conservation between human and mouse (Nelles (2003)).
Misc
Please input misc information here.
Transcriptomic Nomeclature
Please input transcriptomic nomeclature information here.
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
Please input related labs here.
References
Please input cited references here.
Basic Information
| Transcript ID |
NONHSAT074775 |
| Source |
NONCODE4.0 |
| Same with |
, |
| Classification |
intergenic |
| Length |
1187 nt |
| Genomic location |
chr2+:145275982..145278683 |
| Exon number |
4 |
| Exons |
145275982..145276142,145277526..145277677,145277782..145277984,145278013..145278683 |
| Genome context |
|
| Sequence |
000001 GCTGTGCCTC GAGGATTAGT TTAAACAGGG GGCTATAAAA GATGTAACAG ATGCAAACTG TAACACAAGG GCCATTAACC 000080
000081 CTTTCTCTGC CGGGCACACT CAGTCCCCAC GCCCCACACC TATTGTCTCC TGTGCTAGAA GCTTTGCAGA AAACCTGGAA 000160 000161 ATTTTGGCCA GAAATGGTGA GAAGAAAAAG CATGAAGAAG CCGCGAAGTG TGGGGGAGAA AAAGGTGGAA GCGAAGAAAC 000240 000241 AGCTCCCGGA GCAAACTGTA CAAAAACCTC GCCAAGAGTG TCGGGAGGCA GGACCGTTAT TCCTGCAGAG CAGGAGAGAG 000320 000321 ACGAGAGACC CTGAAACACG CGCCACCTAT CTTTGTGGGG AGGGATAATT GAAGCGCCCT GAGCGTGAGC ATCATGTGAA 000400 000401 AACGTGATCG CCAAGTTTCT CTCTGGGAAA GGATCTGGGA TAGATTATAC CTTGAAGTCT CCGCAAACGC TTTAGTGGAA 000480 000481 GAAATGAAAT TCCACCTCCC TCCCTTCCTC CTCTCCCTCC CTCCCTTCTC CCCCCCTCCA CCCCCCCCTC CCCGCCCGTC 000560 000561 AAGCCTTTGG CATCATTATC CTCATCACTA AATCCTACAG AGTACAGGGC GGAAAACGGT GCACACCATT CACAGAACTG 000640 000641 GAGAACTCCA AGGGGCGAAA GTTAAAGGGA AAGATCCCGG GTCCTCAATC CAGATAGTCT CTTCTTATAC AGATATCTCT 000720 000721 AATGACCAGA TTTGAGATGC ACATCAAATT GTGTAGGTAT CTCAGTACAG CTTCTGGAAC AAAGTTCTCT GCCCTTTCTC 000800 000801 TTATTGTTAT TTTTTTCTTT TTAGGTACCA GAGCCAGAAA AAAAAATGCT GCATGGGAGC TGCATCTTAG GGCATGTGTA 000880 000881 TTAGGGTGTG TGCATGATGA ATTTCTGGAC TGGATCCCAA TATTAAAAAG TAGTTTGGCA TTTTAATAAA GGGTCTCTAA 000960 000961 GTAAATTAAA ATAGAACACT CGGTTGGCCG ATCTCTGAAT CTCTCTACAC CTCGGGGAGA CCTCACTACA AAGTAAGGGA 001040 001041 GAGTGTGTAG GGAGGCAGGA GGAGAAACGA GAAAGGCCAT AGAGAAACTT AGCAGGGAAG GGAGAGCATG ATATTAAACG 001120 001121 GCATGGGGTC TAAGTTTTGG AGTATATATT TTTTGATATT ACAATTAAAG TAAGATTAAA AAGAAAA |
