Difference between revisions of "Lnc-EVX1-9:1"
Chunlei Yu (talk | contribs) (→Labs working on this lncRNA) |
Chunlei Yu (talk | contribs) (→Labs working on this lncRNA) |
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==Annotated Information== | ==Annotated Information== | ||
===Name=== | ===Name=== | ||
| − | HOXA-AS3: "HOXA cluster antisense RNA 3 (non-protein coding)" | + | ''HOXA-AS3'': "HOXA cluster antisense RNA 3 (non-protein coding)" |
HOXA6as | HOXA6as | ||
===Characteristics=== | ===Characteristics=== | ||
| − | + | HOXA6as located between HOXA6-A7, whose tissue-specific expression patterns that in some cases resemble the expression profile of sense transcripts.<ref name="ref2" /> | |
===Function=== | ===Function=== | ||
| − | + | HOXA6as may be a regarded as universal reference being applicable for the accurate normalisation of lncRNA expression profiling in various glioma (WHO-Grades II-IV) alone and in combination with brain tissue.<ref name="ref1" /> | |
===Expression=== | ===Expression=== | ||
| − | + | [[File:Stably expressed lncRNAs suitable for studies comparing different glioma entities.jpg|right|thumb|500px|'''Stably expressed lncRNAs suitable for studies comparing different glioma entities.'''<ref name="ref1" />]] | |
| − | + | HOXA6as, which showed stable expression in all investigated brain regions, may be regarded as an universal normaliser suitable for a broad range of lncRNA studies <ref name="ref1" />. | |
| − | HOXA6as | ||
| − | |||
| − | = | + | HOXA6as, like many cases OS-intergenic transcripts, is coexpressed with adjacent coding HOX genes <ref name="ref2" />. |
| − | |||
| − | |||
| − | |||
===Regulation=== | ===Regulation=== | ||
| Line 38: | Line 33: | ||
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
| + | * Dulbecco Telethon Institute, Naples, Italy. <ref name="ref2" /> | ||
* Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians-University. <ref name="ref1" /> | * Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians-University. <ref name="ref1" /> | ||
| Line 43: | Line 39: | ||
<references> | <references> | ||
<ref name="ref1">Kraus TF, Greiner A, Guibourt V, Lisec K, Kretzschmar HA. Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma[J]. Journal of Cancer. 2015,6(2):111-9.</ref>(1) | <ref name="ref1">Kraus TF, Greiner A, Guibourt V, Lisec K, Kretzschmar HA. Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma[J]. Journal of Cancer. 2015,6(2):111-9.</ref>(1) | ||
| + | <ref name="ref2">Sessa L, Breiling A, Lavorgna G, Silvestri L, Casari G, Orlando V. Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster[J]. Rna. 2007,13(2):223-39.</ref>(1) | ||
</references> | </references> | ||
Latest revision as of 13:46, 24 June 2016
Please input one-sentence summary here.
Contents
Annotated Information
Name
HOXA-AS3: "HOXA cluster antisense RNA 3 (non-protein coding)"
HOXA6as
Characteristics
HOXA6as located between HOXA6-A7, whose tissue-specific expression patterns that in some cases resemble the expression profile of sense transcripts.[1]
Function
HOXA6as may be a regarded as universal reference being applicable for the accurate normalisation of lncRNA expression profiling in various glioma (WHO-Grades II-IV) alone and in combination with brain tissue.[2]
Expression
Stably expressed lncRNAs suitable for studies comparing different glioma entities.[2]
HOXA6as, which showed stable expression in all investigated brain regions, may be regarded as an universal normaliser suitable for a broad range of lncRNA studies [2].
HOXA6as, like many cases OS-intergenic transcripts, is coexpressed with adjacent coding HOX genes [1].
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
- Dulbecco Telethon Institute, Naples, Italy. [1]
- Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians-University. [2]
References
- ↑ 1.0 1.1 1.2 Sessa L, Breiling A, Lavorgna G, Silvestri L, Casari G, Orlando V. Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster[J]. Rna. 2007,13(2):223-39.
- ↑ 2.0 2.1 2.2 2.3 Kraus TF, Greiner A, Guibourt V, Lisec K, Kretzschmar HA. Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma[J]. Journal of Cancer. 2015,6(2):111-9.
Basic Information
| Transcript ID |
lnc-EVX1-9:1 |
| Source |
LNCipedia2.1 |
| Same with |
, |
| Classification |
intergenic |
| Length |
2354 nt |
| Genomic location |
chr7+:27186781..27193904 |
| Exon number |
, |
| Exons |
, |
| Genome context |
|
| Sequence |
000001 TTCTCTTTTA AGAAGCCAAA GAAACTTTGC TGGTTCTTTC ATCCTTTCTT TCTCTCTATT CCTCTTTCTA CTCTGTTTCC 000080
000081 TCCTTCTTTC TTTCTTTTCC TGCCTCCTTT CCCCTCTCCC TCCACTGTCT TGGGATATGT CTTACCCGCG CAGGAGTTCA 000160 000161 TCCGCTGCAT CCAAGGGTAA ACCGGGCTCG TGTACTTCCG GTCGGCGCCT TCGTCATGGA GTGCTTTGCC CTGCCCGCTG 000240 000241 CTGCTGTCGG AATTCCACCC ACGCACCTAT TCCCCCTCCC AGCGCTTCAG ACACCTCTCT CATCGAAAAA CCGGGCGAAG 000320 000321 GGAAGCCGGC AACGAGCGGA GAACTCTGGC TGAATTAACG GTGGCTCCCA GAAGCTCCTG CCCCTCTGAC AGCTGTCGCT 000400 000401 TGGGCAGCCC GAGAGAAGAA TTGTCCTCTT TCCTGGTGCC AGAGGACGCA GGAAATTAGC CAGGTTGCGA GTTGCAAAGC 000480 000481 TGCTGCCGCG GCGCCGGGAA CGGAGCGCGC CCAATCTCCA GCGGGAGCCG CCAGGCCTGG CCTGGCCTGG CCGGGGCTTC 000560 000561 CCTTCGCTCG CCATCTCCGG ACAAAGCACA GCCGAGCCCG GCTGGAAGGC AGAGCTCCGA AGCAGGCAGG ACGGAGTGGA 000640 000641 GCAAAAGAAT GCGGCTCTAT TCTCGCAAGG GAAATTATAA AAAAGTTCAT GTTCACGGTT CTCATCCACA TGACCGACAG 000720 000721 CGGCCAATGG AAGGGCCGAA CAACTCATAA AGTTGTATTG CAAAGTTGTA AATTTTCATA AACAACAACG GATTTATGAC 000800 000801 CCTTTCCCCA TCACTGAGAG GAGGCAGCTC TTACACCGGC GCCATCTTAC CACCGAGGCC GCCCCGACTT GGGGCCTCAG 000880 000881 GTTTTACAGA CCCTTTTGGG CCAGGTTTTA CTAAAAGAGC CATAAGAAGC GGGCCCAGCC CAGGCAGGAG ACTGGAGACG 000960 000961 AGGTCTTGCA GGCGGAACTC AGGATGCTCT GAGCTGCCCG CACAACCCCT GGACCTTCAC CCCTCGCCCC TTCCCCGCAT 001040 001041 CCAGCTGCCC CAGCCCCTGC CCAGGCTGCG TAGCCTAGCG GGGGTCTGCG GTCCTAGCCC CTCCCCGCGC CACCTACTGC 001120 001121 AGTGCCGGAC CCTGGGGCCC CCTCGCCTGG TCTGCAGGCG GGGTGGGGAC CTTAAATCCC ATTTCCTAGC CTGGGGCTGG 001200 001201 GTTCAGGGCG CATGCGAATC CGGAATCAGC TCTGGGTAAT GCCCCTTTCC AAGCCCACTG CTCAGCCTTA GAGGAAAGTG 001280 001281 TGGATTTGAA ATTTCCTCAT GGAATTGATG GAGGTTTTTA GGTAGATTCA TAGAATATAA CGTATCTACC AAAGATTCCG 001360 001361 TTTTCAAGGG ATCTAGAAGA TGTTAGTGCA CACGCAAAAA CCAGACAAAC GTCTCTACAC GGATAAAGGC ACATATACAA 001440 001441 TTATGCACAC AGGGAAGGGC ATACACTCTA TTGTGGGCAC AGAATGACAT GCAATTATGG ACACACAAAA ACACATGCAC 001520 001521 CCAATTATGG ACACCAAAAT ATATACAATT GTGGAATTAG GTAAAAACAC ACACACAGAA ATACATACAC AGAAAAATAA 001600 001601 GCACATACTC ATACAAATAC ACACATAAAA ATACATTAAA AAGATACATG ACACCAATAC ATGGGTACCC AACACTTGGA 001680 001681 CCATCACAAG GACAGCCACC CCACTTTTGC TTCCCCACTG CCCCCTGCCC TCCAGCCATA CTCACCTCCC CTTTCCCAGT 001760 001761 CCCCTCTGGA TAAGGCAGTC CACATTTTTC TTTGTCACCA CGCATCTTTA TTTTCGGTTA CATAAAACAC AGCTGGGCTG 001840 001841 GGAAGTGTGC CTTCCCTGAA CCCCAGGATG GAGCTGAGCA GGGTACAGGA CAACACAGGA GATGAAGGGC ATTGCGGAGG 001920 001921 GCATTGGACC TCCCCACCCA CTACAGTTAA CTCAAGACAA CATACCATGC TACAAAGTCA CCCCATTAAC ACATCCTTTC 002000 002001 CAAGTCAAGA CACTGCCTTA CAAATGAACT CCAAGACTAT AGAAATGATA AAAAAAAATC TTGTTCAAAT ATACAGTATC 002080 002081 TGCTATTATA GGAAACATCA GGGCGTACAT ATTTAACACA GCTGAACAGT AAGATACAGG AGCCAGAGGA AAGGACAGCG 002160 002161 AAGCTGGAAG CATCTCCACA GTCCTGCTAA GCAGAAGCTA ACCCACAGAT CTGCAGCCAG CTCAGGAACA TTCCCCTCCA 002240 002241 GAAGTGGGGG TTGATGGGCC TGAGCTGTGG GTGCCAAGCC AGAGAAGGAG GGATTGATTC TAGGGTGCAA GCACTTAGGA 002320 002321 TGCTTTTTGG AATAAATATA TTATTTTTCG ATTT |
