Difference between revisions of "LINC00998"
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LINC00998 | + | LINC00998:long intergenic non-protein coding RNA 998 |
| − | + | ===Function=== | |
| − | long intergenic non-protein coding RNA 998 | + | The SNP site, rs12526133, is strongly associated with MDD (Major depressive disorder)(χ2 = 11.68, P = 6.3E − 04), and it is located in LINC01108. Therefore, LINC01108 is most likely associated with MDD <ref name="ref1" />. |
| − | === | + | ===Expression=== |
| − | + | The expression of LINC00998 is significantly lower in MDD patients than controls based on microarray analysis (FC=0.11,P<0.001) <ref name="ref1" />. | |
| − | === | + | ===Disease=== |
| − | + | Major depressive disorder <ref name="ref1" /> | |
| − | === | + | |
| − | + | ==Labs working on this lncRNA== | |
| − | === | + | *State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences & Neuroscience Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Tsinghua University, China. |
| − | + | ||
| − | + | ==References== | |
| − | + | <references> | |
| − | == | + | <ref name="ref1"> |
| − | + | Ye N, Rao S, Du T, Hu H, Liu Z, Shen Y, Xu Q. Intergenic variants may | |
| − | == | + | predispose to major depression disorder through regulation of long non-coding RNA |
| − | + | expression. Gene. 2017 Feb 15;601:21-26. | |
| − | = | + | </ref>(1) |
| − | major | + | </references> |
Latest revision as of 05:33, 17 November 2017
Contents
Annotated Information
Name
LINC00998:long intergenic non-protein coding RNA 998
Function
The SNP site, rs12526133, is strongly associated with MDD (Major depressive disorder)(χ2 = 11.68, P = 6.3E − 04), and it is located in LINC01108. Therefore, LINC01108 is most likely associated with MDD [1].
Expression
The expression of LINC00998 is significantly lower in MDD patients than controls based on microarray analysis (FC=0.11,P<0.001) [1].
Disease
Major depressive disorder [1]
Labs working on this lncRNA
- State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences & Neuroscience Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Tsinghua University, China.
