Difference between revisions of "FGF14-AS2"

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==Annotated Information==
 
==Annotated Information==
 +
[[File:FGF14-AS2 expression in breast cancer in TCGA cohort.jpg|right|thumb|200px|'''FGF14-AS2 expression in breast cancer in TCGA cohort.'''<ref name="ref1" />]]
 +
[[File:FGF14-AS2 expression in breast cancer in validated cohort.jpg|right|thumb|200px|'''FGF14-AS2 expression in breast cancer in validated cohort.'''<ref name="ref1" />]]
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[[File:Kaplan–Meier analysis for the overall survival of breast cancer patients with different expression of FGF14-AS2 in TCGA cohort.jpg|right|thumb|200px|'''Kaplan–Meier analysis for the overall survival of breast cancer patients with different expression of FGF14-AS2 in TCGA cohort.'''<ref name="ref1" />]]
 
===Approved Symbol===
 
===Approved Symbol===
 
FGF14-AS2 (FGF14 antisense RNA 2)
 
FGF14-AS2 (FGF14 antisense RNA 2)
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13q33.1
 
13q33.1
 
===RefSeq ID===
 
===RefSeq ID===
NR_036487
 
===RefSeq(supplied by NCBI)===
 
 
NR_036487
 
NR_036487
 
===Expression===
 
===Expression===
[[File:FGF14-AS2 expression in breast cancer in validated cohort..jpg|right|thumb|400px|'''FGF14-AS2 expression in breast cancer in validated cohort.Patients were divided into FGF14-AS2 low expression group and FGF14-AS2 high expression group according to whether FGF14-AS2 was down-regulated or up-regulated in their tumor tissue samples compared with
+
Compared with adjacent non-cancerous breast tissues, FGF14-AS2 is down-regulated in breast cancer.<ref name="ref1" />
the corresponding adjacent noncancerous tissue samples.'''<ref name="ref1" />]]
 
<ref name="ref1" />.
 
 
 
 
{| class='wikitable' style="text-align:center"
 
{| class='wikitable' style="text-align:center"
 
|-
 
|-
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| | 5'-AGGTTCATAGTTGCCAGAC- 3'<ref name="ref1" />
 
| | 5'-AGGTTCATAGTTGCCAGAC- 3'<ref name="ref1" />
 
|}
 
|}
Compared with adjacent non-cancerous breast tissues, FGF14-AS2 is down-regulated in breast cancer.<ref name="ref1" />
+
===Function===
===pubmed IDs===
+
FGF14-AS2 is involved in the progress of breast cancer and it plays a tumor suppressor gene role.<ref name="ref1" />
26820525
 
 
===Disease===
 
===Disease===
breast cancer
+
breast cancer <ref name="ref1" />
 
==Labs working on this lncRNA==
 
==Labs working on this lncRNA==
 
* Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
 
* Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
 
 
==References==
 
==References==
 
<references>
 
<references>
<ref name="ref1">  
+
<ref name="ref1">Yang, F., et al., A novel long non-coding RNA FGF14-AS2 is correlated with progression and prognosis in breast cancer. Biochem Biophys Res Commun, 2016. 470(3): p. 479-483.
 
</ref>(1)
 
</ref>(1)
 
</references>
 
</references>

Latest revision as of 07:08, 15 October 2017

Annotated Information

FGF14-AS2 expression in breast cancer in TCGA cohort.[1]
FGF14-AS2 expression in breast cancer in validated cohort.[1]
Kaplan–Meier analysis for the overall survival of breast cancer patients with different expression of FGF14-AS2 in TCGA cohort.[1]

Approved Symbol

FGF14-AS2 (FGF14 antisense RNA 2)

Chromosome

13q33.1

RefSeq ID

NR_036487

Expression

Compared with adjacent non-cancerous breast tissues, FGF14-AS2 is down-regulated in breast cancer.[1]

Experiment Forward primer Reverse primer
qRT-PCR 5'-AGTTCCAGTTACCATCTTCA- 3' 5'-AGGTTCATAGTTGCCAGAC- 3'[1]

Function

FGF14-AS2 is involved in the progress of breast cancer and it plays a tumor suppressor gene role.[1]

Disease

breast cancer [1]

Labs working on this lncRNA

  • Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Yang, F., et al., A novel long non-coding RNA FGF14-AS2 is correlated with progression and prognosis in breast cancer. Biochem Biophys Res Commun, 2016. 470(3): p. 479-483.