Difference between revisions of "FOXD2-AS1"

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==Annotated Information==
 
==Annotated Information==
 
[[File: LncRNA FOXD2-AS was highly expressed in NSCLC tumors.jpg|right|thumb|400px|'''LncRNA FOXD2-AS was highly expressed in NSCLC tumors''' <ref name="ref1" />.]]
 
[[File: LncRNA FOXD2-AS was highly expressed in NSCLC tumors.jpg|right|thumb|400px|'''LncRNA FOXD2-AS was highly expressed in NSCLC tumors''' <ref name="ref1" />.]]
[[File: FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells.jpg|right|thumb|400px|'''FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells.''' <ref name="ref1" />.]]
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[[File: FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells.jpg|right|thumb|400px|'''FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells''' <ref name="ref1" />.]]
  
 
===Approved Symbol===
 
===Approved Symbol===
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===RefSeq(supplied by NCBI)===
 
===RefSeq(supplied by NCBI)===
 
NR_026878
 
NR_026878
===pubmed IDs===
 
28132805
 
 
===Disease===
 
===Disease===
 
Lung cancer
 
Lung cancer
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===Expression===
 
===Expression===
lncRNA FOXD2-AS1 had significantly high expression in NSCLC tissues.<ref name="ref1" />.To be specific, high expression of lncRNA FOXD2-AS1 was shown in 23 cases of 45 (53.3%), in which unchanged was revealed in 10 cases (22%) and down-regulation in 12 cases (24%) <ref name="ref1" />
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Compared with the adjacent tissues,lncRNA FOXD2-AS1 had significantly high expression in NSCLC tissues.<ref name="ref1" />.To be specific, high expression of lncRNA FOXD2-AS1 was shown in 23 cases of 45 (53.3%), in which unchanged was revealed in 10 cases (22%) and down-regulation in 12 cases (24%) <ref name="ref1" />
  
 
{| class='wikitable' style="text-align:center"
 
{| class='wikitable' style="text-align:center"
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==Labs working on this lncRNA==
 
==Labs working on this lncRNA==
* Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China.
 
 
* Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China. Electronic address: wchqba@163.com.
 
* Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China. Electronic address: wchqba@163.com.
  

Latest revision as of 11:31, 19 November 2017

Annotated Information

LncRNA FOXD2-AS was highly expressed in NSCLC tumors [1].
FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells [1].

Approved Symbol

FOXD2-AS1 (FOXD2 antisense RNA 1 (head to head))

Synonyms

MGC12982

Chromosome

1p33

RefSeq(supplied by NCBI)

NR_026878

Disease

Lung cancer

Function

Loss- and gain-function assays suggested that FOXD2-AS1 remarkably modulates the tumorigenesis of NSCLC through Wnt/β-catenin signaling.[1] FOXD2-AS1 overexpression promotes NSCLC progression.[1]

Expression

Compared with the adjacent tissues,lncRNA FOXD2-AS1 had significantly high expression in NSCLC tissues.[1].To be specific, high expression of lncRNA FOXD2-AS1 was shown in 23 cases of 45 (53.3%), in which unchanged was revealed in 10 cases (22%) and down-regulation in 12 cases (24%) [1]

Experiment Forward primer Reverse primer
qRT-PCR 5'-TGGACCTAGCTGCAGCTCCA- 3' 5'-AGTTGAAGGTGCACACACTG- 3'[1]

Labs working on this lncRNA

  • Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China. Electronic address: wchqba@163.com.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Rong, L., R. Zhao, and J. Lu, Highly expressed long non-coding RNA FOXD2-AS1 promotes non-small cell lung cancer progression via Wnt/beta-catenin signaling. Biochem Biophys Res Commun, 2017. 484(3): p. 586-591.