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− | [[File: Sequence changes in the origin of CLLU1 from noncoding DNA.jpg|right|thumb|400px|'''Sequence changes in the origin of CLLU1 from noncoding DNA''' <ref name="ref1" />.]]
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− | [[File: Genomic organization and structure of CLLU1 transcripts.gif|right|thumb|400px|'''Genomic organization and structure of CLLU1 transcripts''' <ref name="ref3" />.]]
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− | [[File: Similarity between the CLLU1-encoded protein and IL-4.gif|right|thumb|400px|'''Similarity between the CLLU1-encoded protein and IL-4.''' <ref name="ref3" />.]]
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| ==Annotated Information== | | ==Annotated Information== |
| ===Approved Symbol=== | | ===Approved Symbol=== |
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| ===pubmed IDs=== | | ===pubmed IDs=== |
| "19726446, 22102831" | | "19726446, 22102831" |
− | ===Characteristics===
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− | CLLU1 is located on chromosome 12q22, surrounded by genes that are active in germinal center B cells and CLL cells <ref name="ref3" />. The CLLU1 region does not include any known miRNAs.<ref name="ref3" />
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− | ===Expression===
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− | It is originally recognized as a highly expressed gene in chronic lymphocytic leukemia (CLL).<ref name="ref3" />
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− | ==Labs working on this lncRNA==
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− | * Smurfit Institute of Genetics, University of Dublin, Trinity College, Ireland.<ref name="ref1" />
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− | * Department of Hematology, 4041, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DK. am.buhl@get2net.dk <ref name="ref3" />
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− | ==References==
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− | <references>
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− | <ref name="ref1"> Knowles, D.G. and A. McLysaght, Recent de novo origin of human protein-coding genes. Genome Res, 2009. 19(10): p. 1752-9.
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− | </ref>(1)
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− | <ref name="ref3"> Buhl, A.M., et al., Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia. Blood, 2006. 107(7): p. 2904-11.
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− | </ref>(2)
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− | </references>
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