Difference between revisions of "CLLU1"

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[[File: Sequence changes in the origin of CLLU1 from noncoding DNA.jpg|right|thumb|400px|'''Sequence changes in the origin of CLLU1 from noncoding DNA''' <ref name="ref1" />.]]
 
[[File: Genomic organization and structure of CLLU1 transcripts.gif|right|thumb|400px|'''Genomic organization and structure of CLLU1 transcripts''' <ref name="ref3" />.]]
 
[[File: Similarity between the CLLU1-encoded protein and IL-4.gif|right|thumb|400px|'''Similarity between the CLLU1-encoded protein and IL-4.''' <ref name="ref3" />.]]
 
 
==Annotated Information==
 
==Annotated Information==
 
===Approved Symbol===
 
===Approved Symbol===
Line 15: Line 12:
 
===pubmed IDs===
 
===pubmed IDs===
 
"19726446, 22102831"
 
"19726446, 22102831"
===Characteristics===
 
CLLU1 is located on chromosome 12q22, surrounded by genes that are active in germinal center B cells and CLL cells <ref name="ref3" />. The CLLU1 region does not include any known miRNAs.<ref name="ref3" />
 
 
===Expression===
 
It is originally recognized as a highly expressed gene in chronic lymphocytic leukemia (CLL).<ref name="ref3" />
 
 
==Labs working on this lncRNA==
 
* Smurfit Institute of Genetics, University of Dublin, Trinity College, Ireland.<ref name="ref1" />
 
* Department of Hematology, 4041, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DK. am.buhl@get2net.dk <ref name="ref3" />
 
 
==References==
 
<references>
 
<ref name="ref1"> Knowles, D.G. and A. McLysaght, Recent de novo origin of human protein-coding genes. Genome Res, 2009. 19(10): p. 1752-9.
 
</ref>(1)
 
<ref name="ref3"> Buhl, A.M., et al., Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia. Blood, 2006. 107(7): p. 2904-11.
 
</ref>(2)
 
</references>
 

Latest revision as of 09:59, 19 November 2017

Annotated Information

Approved Symbol

CLLU1 (chronic lymphocytic leukemia up-regulated 1

Chromosome

12q22

RefSeq ID

NM_001025233

OMIM ID

616988

RefSeq(supplied by NCBI)

NR_027932

pubmed IDs

"19726446, 22102831"