Difference between revisions of "MIR122HG"
| (3 intermediate revisions by one other user not shown) | |||
| Line 1: | Line 1: | ||
| − | |||
==Annotated Information== | ==Annotated Information== | ||
===Name=== | ===Name=== | ||
| − | MIR122HG | + | Approved symbol:MIR122HG |
| − | + | ||
| − | lnc-pri-miR-122 | + | Approved name:MIR122 host gene |
| − | + | ||
| − | + | HGNC ID:HGNC:53821 | |
| − | + | ||
| − | + | Alias symbol:lnc-pri-miR-122 | |
| + | |||
| + | RefSeq ID:NR_170244 | ||
===Characteristic=== | ===Characteristic=== | ||
| − | + | MIR122HG transcripts are capped but not polyadenylated<ref name="ref1" /> | |
| − | + | MIR122HG 3' end is generated by Drosha cleavage and not by CPA<ref name="ref1" /> | |
Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.<ref name="ref1" /> | Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.<ref name="ref1" /> | ||
===Expression=== | ===Expression=== | ||
| − | + | MIR122HG transcripts are capped but not polyadenylated<ref name="ref1" /> | |
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Latest revision as of 15:05, 25 January 2021
Contents
Annotated Information
Name
Approved symbol:MIR122HG
Approved name:MIR122 host gene
HGNC ID:HGNC:53821
Alias symbol:lnc-pri-miR-122
RefSeq ID:NR_170244
Characteristic
MIR122HG transcripts are capped but not polyadenylated[1] MIR122HG 3' end is generated by Drosha cleavage and not by CPA[1] Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.[1]
Expression
MIR122HG transcripts are capped but not polyadenylated[1]
Labs working on this lncRNA
- Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
References
- ↑ 1.0 1.1 1.2 1.3 Dhir A, Dhir S, Proudfoot NJ, Jopling CL. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nat Struct Mol Biol. 2015 Apr;22(4):319-27. doi: 10.1038/nsmb.2982. Epub 2015 Mar 2. PubMed PMID: 25730776; PubMed Central PMCID: PMC4492989.
