Difference between revisions of "CASC2"
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===Ensembl ID=== | ===Ensembl ID=== | ||
ENSG00000177640 | ENSG00000177640 | ||
| − | |||
| − | |||
===Function=== | ===Function=== | ||
| − | CASC2 up-regulates PTEN through direct inhibiting miR-181a and plays an important role in glioma sensitivity to TMZ and may serve as a potential target for cancer diagnosis and treatment.<ref name="ref1"> | + | CASC2 up-regulates PTEN through direct inhibiting miR-181a and plays an important role in glioma sensitivity to TMZ and may serve as a potential target for cancer diagnosis and treatment.<ref name="ref1" /> |
| − | + | ===Expression=== | |
| + | CASC2 expression is down-regulated in glioma tissues and cell lines, and is related to a clinicopathologic features and shorter survival time.<ref name="ref1" /> | ||
===Sequence=== | ===Sequence=== | ||
>gi|223972640|ref|NR_026939.1| Homo sapiens cancer susceptibility candidate 2 (non-protein coding) (CASC2), transcript variant 1, long non-coding RNA | >gi|223972640|ref|NR_026939.1| Homo sapiens cancer susceptibility candidate 2 (non-protein coding) (CASC2), transcript variant 1, long non-coding RNA | ||
Latest revision as of 07:14, 10 August 2019
Contents
Annotated Information
Approved Symbol
CASC2
Approved Name
cancer susceptibility candidate 2 (non-protein coding)
Previous Symbols
C10orf5
Chromosome
10q26.12
RefSeq ID
NR_026939
OMIM ID
608598
Ensembl ID
ENSG00000177640
Function
CASC2 up-regulates PTEN through direct inhibiting miR-181a and plays an important role in glioma sensitivity to TMZ and may serve as a potential target for cancer diagnosis and treatment.[1]
Expression
CASC2 expression is down-regulated in glioma tissues and cell lines, and is related to a clinicopathologic features and shorter survival time.[1]
Sequence
>gi|223972640|ref|NR_026939.1| Homo sapiens cancer susceptibility candidate 2 (non-protein coding) (CASC2), transcript variant 1, long non-coding RNA
000001 AGCGGGCTGC AGGGCTGCGG GCGCTTGGTT CGGCCTGGCC CGGCCGGCGG CTCCTAACAC CGGGCGGGCG GCTGCGGCGG 000080
000081 CACTTCCGGG TTGGCCTTCT CCATGTTGGT CTCGGGAACG TGAAGGGGCG GGGCCTCGAG GTCAGGGGTC AGCACCTCCC 000160
000161 TGGTTGCCGT GGCGACTGGA GGCGCGCGAC GCGGGCGCAA TGGCGGGGAC CCGGGGCTTG ATGCTGCTTG GGCCTGGCCC 000240
000241 AGTGGCGGGT CCTAGGGACG TGGGTACCTG CAGAGGCCGG CAGATGGAGA TTCAGAAACA TAAGGACAAC AAGAAACTTC 000320
000321 CCCAAGGTAT CATTATAGTC TTTAGACTTC AGACACACAC CACACCTCAA ATATATACAC AACTGAAAGG AAAATTAAGG 000400
000401 AAGTTTTTCA AAGAACCCTA TTCCGAGTAA GAAGTGTGTT GCATGAATTT CTAAGAGCCA GAAAATGCAT GACACAGGAG 000480
000481 AAGATGTACC CTCATCTGTT CAGTGAGAGA TGTGCAAATC AACATCAACA CAGAACTGCT GAAGAAAAAA AATATGTCTC 000560
000561 TGAAAAGCAA CTTATTCACT GGAGATGTGA GGAGCCATCC GCACATCACA ATTCTATAGA CATCAAACGC ATGAAGCATT 000640
000641 TCGGATCTGC TTTAAGACTG AGGCAGACTT TCCATCTGGA CACAGCCGAC CATCCATGTG TCATTACAAT GAATCCAGCA 000720
000721 CTTCCCTGGA AGCTGGAAGG GTCAAATTCA ACTTCAACTC TGCCACTTCC TGCTTAACTT GCTGTTTAAC CTTGGGCAAG 000800
000801 CTGCCATCCC ACACGAGGCC GAAGGTGTCG GTTTTTAAAA TACAGAAATT TGGTTCCATG AGGGATTATC AATATACTGC 000880
000881 TGGTGGGCCA AATTCCATCT GCTACTTGCC TTTGTAAATA AAGTTTTATT GAAACACAAA CATGCCCATT AGTTTACTCT 000960
000961 TGTCTGTGAC TACAAGGGCA AAGTTGAATA GTTGTTACAG AGACCATCAG GCTCACAAAG CCTAGGTTAT TTACTATCTG 001040
001041 CCCATTTACA GAGTAAGTTT GCCAGCCCTG GACTGGATAA TTTTTTGAGT TCTTTCTAAT TCTAGAATTC TTTATATATT 001120
001121 TTATGAAACC CCTAATGTTT ATATATTAAT TATTTCAATA CCCGTGTCTT TACTGAGTCC CTCCTATGAA GCATACATCA 001200
001201 AGACATATGT GTGATACATT AACTAAACTT TTAACAGTAT CTTAAATAGG ATTTCAATGA CTAACAGCTC TTGGAAATAT 001280
001281 CCAAGGTAAC ATTTGGGGGC AAATGTCTTA TGATTTGATT ATCATTGGTA AATAGAGCAT ATCTTTTTTT CCACTAACAA 001360
001361 TGTTTAAGAA GTTAAAAAAA AATCAAGAAA ACCCCGTATG GCACTAGAGA CTTATTGCAT TAAGACATCA TCTTAACAGA 001440
001441 TTGTTTAGTT TTGGTAATAT AATTTGACAT CTAAACATAA GCTGAGAGGG ATCTCCCTCA AAACCTTTGA TAATATGATT 001520
001521 CATTGTCAAA TGTTTGTTTT GCCTATCTGG CACTCATTAA TTAATTCTTT TTAATATAGC TTGGATTTAC TGATTTTGAA 001600
001601 AAAGAGAATT ATTCTTATTG ATGTTGCTAA AATATCCAGG TGGCTTGAAT TTCACCAACT AGATAGTTTA ATCTAGCACA 001680
001681 TTTGTGTAGC CCTAATCAAA TCTTTACTAA CAGATGTGAG AAGCCCAGTA CTGGAGCTAA TGTTTGTGTC TCAATGATAA 001760
001761 TTAAATTAGC TTAATAAGGA AAATAAATGA ACAATAATCA CCAAAATTTT TCCCTAAACC TGTGTTATAG TCTTAAAAAC 001840
001841 ATTTTTTCCC CTATGGAGGC TTTTGGTAAT AAAACACAAA TTGAGGGATT TTAATTAAAA GAAATTTTTT TTTCAAGAAC 001920
001921 TGGTCATGTA CTAAATTGCT TATAATCAAA TAATCAAGTA GCATTTCTTT TATTATAAGA GCAAAACCTA TAATTAAGCC 002000
002001 AAAATTCAAA TTTGTTTTTA AAGGTTGAAT AATCTTTTGT TTTGGCCAAT AGTATGTGGA TTTTTTTTTT AAGTATTATC 002080
002081 TCTTTGTAGT ATTTTCTAAT GGATAGGAAA TGCCTTTCTC AGGTTGAATG ATTATTTCCA CATAGAATTA GTTCCTGCTT 002160
002161 ACAACAGTGC TCCACTAATG TAATGGCTCG GTGAATTGGC TTTATAATTC ATTAATCATA GCTCACATTG AGCTTTTGGC 002240
002241 TCCAGGTGAC AGTGCCCACC ACAGGCCAAA TAACTTCTCA TTTAAAGGCA ATTTGTACAA ATAGGGAAGG TGAGAATTCT 002320
002321 CACAGTCCCA GAGGGATTGA AGAGTTTTAA AAAACCAAGA TAAGGCATTT TATGGAAGAC AGGTTGATGG AAGAAAAGTG 002400
002401 GCCATTGGAG GATGAGGCAG ATGGCTTTCC AGGGAGGCCC TGGAGCTGCC ACCATGGGGA AGGCCATGTT GCAGCTGCTG 002480
002481 ATCAGAGCAC ATTGGACGGT GTTTCCGTGT GAACATGAAG ACAATGCTGC CTCTGTTTCT GTGACGCTGT GCTCTGATCT 002560
002561 TGCTGGAGGC GAAGTGGTGT CAGCTGTGCT TACAGGACAG TCAGTGGTGG TAGAAAAGAG GCCAGTGTGA CCTGTGAAGG 002640
002641 ACTGGGCCCC TCTCACTCAA CCTGAGTGCC TGCAGTTGTG GCCACCTTTA TTTGTGTATT CTACTGTATT TATTTATTTG 002720
002721 CCTGGCTAAT TAGCTCTGTG CCACATTCCT AAGCTAGATG TGTCCCTTCA TGTAAGTGAG AGGGAGACAG AAAGAAAGAC 002800
002801 TGAGGTGGGG GGTAGGAGAA AGAGAGGAAA GCAAGCAAGA AGAAAGAGAA AGAGAGAAGA AGAAAGGAAG AGGAAAGAAA 002880
002881 GAGAGAAAGA GAAAGAGAAG GAAGGAAGGA GAAAGAGAAG GAAAGAAGGA GCCTTCTAAT TTTATTTCAT TTCTCCAATA 002960
002961 AATGTTCCTA TATTAAGACT TTAGACAAAG ATTAGAAATA TGATTTGACA GAAAGTGTAT GGATGTGTTG TTCTATTGCA 003040
003041 TTGTAAGTAA AGTATCCATG GCAATATACA AATAATACAG CTCCTACCCC TATTCTCTGT TGTTACTTTC ATGTGTTGTC 003120
003121 TTAACTTTTT AAATTTCAAG ATAATATTGC GCTTATTTAT TTTTCCATGA GGAGGCCTAG GATTTAGCTT GATTAGAAAA 003200
003201 GCTGTGGAAA ATGAATGTGC TAATTACTTT AAATCAAATT GAAAATAAAT TTTATCCTGT TTCATGCAAA ACAAAAAAAA 003280
003281 AAAA
000081 CACTTCCGGG TTGGCCTTCT CCATGTTGGT CTCGGGAACG TGAAGGGGCG GGGCCTCGAG GTCAGGGGTC AGCACCTCCC 000160
000161 TGGTTGCCGT GGCGACTGGA GGCGCGCGAC GCGGGCGCAA TGGCGGGGAC CCGGGGCTTG ATGCTGCTTG GGCCTGGCCC 000240
000241 AGTGGCGGGT CCTAGGGACG TGGGTACCTG CAGAGGCCGG CAGATGGAGA TTCAGAAACA TAAGGACAAC AAGAAACTTC 000320
000321 CCCAAGGTAT CATTATAGTC TTTAGACTTC AGACACACAC CACACCTCAA ATATATACAC AACTGAAAGG AAAATTAAGG 000400
000401 AAGTTTTTCA AAGAACCCTA TTCCGAGTAA GAAGTGTGTT GCATGAATTT CTAAGAGCCA GAAAATGCAT GACACAGGAG 000480
000481 AAGATGTACC CTCATCTGTT CAGTGAGAGA TGTGCAAATC AACATCAACA CAGAACTGCT GAAGAAAAAA AATATGTCTC 000560
000561 TGAAAAGCAA CTTATTCACT GGAGATGTGA GGAGCCATCC GCACATCACA ATTCTATAGA CATCAAACGC ATGAAGCATT 000640
000641 TCGGATCTGC TTTAAGACTG AGGCAGACTT TCCATCTGGA CACAGCCGAC CATCCATGTG TCATTACAAT GAATCCAGCA 000720
000721 CTTCCCTGGA AGCTGGAAGG GTCAAATTCA ACTTCAACTC TGCCACTTCC TGCTTAACTT GCTGTTTAAC CTTGGGCAAG 000800
000801 CTGCCATCCC ACACGAGGCC GAAGGTGTCG GTTTTTAAAA TACAGAAATT TGGTTCCATG AGGGATTATC AATATACTGC 000880
000881 TGGTGGGCCA AATTCCATCT GCTACTTGCC TTTGTAAATA AAGTTTTATT GAAACACAAA CATGCCCATT AGTTTACTCT 000960
000961 TGTCTGTGAC TACAAGGGCA AAGTTGAATA GTTGTTACAG AGACCATCAG GCTCACAAAG CCTAGGTTAT TTACTATCTG 001040
001041 CCCATTTACA GAGTAAGTTT GCCAGCCCTG GACTGGATAA TTTTTTGAGT TCTTTCTAAT TCTAGAATTC TTTATATATT 001120
001121 TTATGAAACC CCTAATGTTT ATATATTAAT TATTTCAATA CCCGTGTCTT TACTGAGTCC CTCCTATGAA GCATACATCA 001200
001201 AGACATATGT GTGATACATT AACTAAACTT TTAACAGTAT CTTAAATAGG ATTTCAATGA CTAACAGCTC TTGGAAATAT 001280
001281 CCAAGGTAAC ATTTGGGGGC AAATGTCTTA TGATTTGATT ATCATTGGTA AATAGAGCAT ATCTTTTTTT CCACTAACAA 001360
001361 TGTTTAAGAA GTTAAAAAAA AATCAAGAAA ACCCCGTATG GCACTAGAGA CTTATTGCAT TAAGACATCA TCTTAACAGA 001440
001441 TTGTTTAGTT TTGGTAATAT AATTTGACAT CTAAACATAA GCTGAGAGGG ATCTCCCTCA AAACCTTTGA TAATATGATT 001520
001521 CATTGTCAAA TGTTTGTTTT GCCTATCTGG CACTCATTAA TTAATTCTTT TTAATATAGC TTGGATTTAC TGATTTTGAA 001600
001601 AAAGAGAATT ATTCTTATTG ATGTTGCTAA AATATCCAGG TGGCTTGAAT TTCACCAACT AGATAGTTTA ATCTAGCACA 001680
001681 TTTGTGTAGC CCTAATCAAA TCTTTACTAA CAGATGTGAG AAGCCCAGTA CTGGAGCTAA TGTTTGTGTC TCAATGATAA 001760
001761 TTAAATTAGC TTAATAAGGA AAATAAATGA ACAATAATCA CCAAAATTTT TCCCTAAACC TGTGTTATAG TCTTAAAAAC 001840
001841 ATTTTTTCCC CTATGGAGGC TTTTGGTAAT AAAACACAAA TTGAGGGATT TTAATTAAAA GAAATTTTTT TTTCAAGAAC 001920
001921 TGGTCATGTA CTAAATTGCT TATAATCAAA TAATCAAGTA GCATTTCTTT TATTATAAGA GCAAAACCTA TAATTAAGCC 002000
002001 AAAATTCAAA TTTGTTTTTA AAGGTTGAAT AATCTTTTGT TTTGGCCAAT AGTATGTGGA TTTTTTTTTT AAGTATTATC 002080
002081 TCTTTGTAGT ATTTTCTAAT GGATAGGAAA TGCCTTTCTC AGGTTGAATG ATTATTTCCA CATAGAATTA GTTCCTGCTT 002160
002161 ACAACAGTGC TCCACTAATG TAATGGCTCG GTGAATTGGC TTTATAATTC ATTAATCATA GCTCACATTG AGCTTTTGGC 002240
002241 TCCAGGTGAC AGTGCCCACC ACAGGCCAAA TAACTTCTCA TTTAAAGGCA ATTTGTACAA ATAGGGAAGG TGAGAATTCT 002320
002321 CACAGTCCCA GAGGGATTGA AGAGTTTTAA AAAACCAAGA TAAGGCATTT TATGGAAGAC AGGTTGATGG AAGAAAAGTG 002400
002401 GCCATTGGAG GATGAGGCAG ATGGCTTTCC AGGGAGGCCC TGGAGCTGCC ACCATGGGGA AGGCCATGTT GCAGCTGCTG 002480
002481 ATCAGAGCAC ATTGGACGGT GTTTCCGTGT GAACATGAAG ACAATGCTGC CTCTGTTTCT GTGACGCTGT GCTCTGATCT 002560
002561 TGCTGGAGGC GAAGTGGTGT CAGCTGTGCT TACAGGACAG TCAGTGGTGG TAGAAAAGAG GCCAGTGTGA CCTGTGAAGG 002640
002641 ACTGGGCCCC TCTCACTCAA CCTGAGTGCC TGCAGTTGTG GCCACCTTTA TTTGTGTATT CTACTGTATT TATTTATTTG 002720
002721 CCTGGCTAAT TAGCTCTGTG CCACATTCCT AAGCTAGATG TGTCCCTTCA TGTAAGTGAG AGGGAGACAG AAAGAAAGAC 002800
002801 TGAGGTGGGG GGTAGGAGAA AGAGAGGAAA GCAAGCAAGA AGAAAGAGAA AGAGAGAAGA AGAAAGGAAG AGGAAAGAAA 002880
002881 GAGAGAAAGA GAAAGAGAAG GAAGGAAGGA GAAAGAGAAG GAAAGAAGGA GCCTTCTAAT TTTATTTCAT TTCTCCAATA 002960
002961 AATGTTCCTA TATTAAGACT TTAGACAAAG ATTAGAAATA TGATTTGACA GAAAGTGTAT GGATGTGTTG TTCTATTGCA 003040
003041 TTGTAAGTAA AGTATCCATG GCAATATACA AATAATACAG CTCCTACCCC TATTCTCTGT TGTTACTTTC ATGTGTTGTC 003120
003121 TTAACTTTTT AAATTTCAAG ATAATATTGC GCTTATTTAT TTTTCCATGA GGAGGCCTAG GATTTAGCTT GATTAGAAAA 003200
003201 GCTGTGGAAA ATGAATGTGC TAATTACTTT AAATCAAATT GAAAATAAAT TTTATCCTGT TTCATGCAAA ACAAAAAAAA 003280
003281 AAAA
Labs working on this lncRNA
- Department of Neurosurgery, Xiangya Hospital, Central South University (CSU), Changsha 410008, P. R. China.
