Difference between revisions of "FAM230H"
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===Name=== | ===Name=== | ||
Approved symbol：FAM230H | Approved symbol：FAM230H | ||
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Approved name：family with sequence similarity 230 member H | Approved name：family with sequence similarity 230 member H | ||
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Alias symbol：AP000552.1 | Alias symbol：AP000552.1 | ||
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| + | HGNC:52423 | ||
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RefSeq ID：NR_136559 | RefSeq ID：NR_136559 | ||
Latest revision as of 10:59, 19 February 2021
FAM230H, a lncRNA gene formed from a large segment of the 3' half of theFAM230C sequence duplicated in chr22.
Contents
Annotated Information
Name
Approved symbol：FAM230H
Approved name：family with sequence similarity 230 member H
Alias symbol：AP000552.1
HGNC:52423
RefSeq ID：NR_136559
Characteristics
This gene belongs to the family of long 8 intergenic non-coding RNA genes in human chromosomal region 22q11.21. This gene carries the TBTA sequence which consists of satellite DNA, Alu elements, and AT-rich sequences.[1]
Function
Functions of RNA transcripts from this family are not known.[1]
Regulation
In a Genome wide study, this lncRNA gene is among top 20 differentially expressed lncRNAs in papillary thyroid carcinoma (PTC) tissues where it is upregulated compared with paired noncancerous thyroid tissues. [2]
Expression
RNA transcripts of these eight FAM230C-related genes are expressed almost exclusively in the testes. [1]
Disease
Papillary thyroid carcinoma [2]
Labs working on this lncRNA
Department of Molecular Genetics and Microbiology, School of Medicine Stony Brook University, Stony Brook, New York, United States of America.
References
- ↑ 1.0 1.1 1.2 Delihas N. A family of long intergenic non-coding RNA genes in human chromosomal region 22q11.2 carry a DNA translocation breakpoint/AT-rich sequence[J]. Plos One. 2018, 13(4):e0195702-e0195702.
- ↑ 2.0 2.1 Lan X, Zhang H, Wang Z, Dong W, Sun W, Shao L et al. Genome-wide analysis of long noncoding RNA expression profile in papillary thyroid carcinoma[J]. Gene. 2015, 569(1):109-117.
Sequence
>gi|100996335|ref|NR_136559.1| Homo sapiens family with sequence similarity 230 member H (FAM230H), long non-coding RNA
000081 GGAACCTGTG TGGCTGCATT CAAGGTGACT CGAAGAAGCC TTCCAAAAAG CATGTGAAAA GGAAGCCCTA CTCTACTACC 000160
000161 AAGGTGACTT CAGGGAGCAC ATTCAATGAG AATACAAGAA GATATGCTGT GCACACCAAC CAGTGTAGGA GACCTCATGG 000240
000241 CTCCCGGGTA AAGAAGAAGA GGTACCCACA AGAAGATGAC TTCCATCATA CAGTCTTCAG CAACCTTGAA AGATTGGACA 000320
000321 AGCTTCAGCC CACTCTTGAA GCCTCTGAGG AGTCTCTAGT TCACAAGGAC AGAGGAGATG GAGAGAGGCC AGTCAACGCG 000400
000401 AGGGTGGTGC AGGTGGCCCC TCTGAGGCTT GAATCTACTC CCCATGAGGA CACCGTACAC GACATCACTA ACGAGGACGC 000480
000481 CACACACGAC ATCGCTAACG AGGATACTGT ACACGACATC GCTAACGAGG CCGCCGACAA GGGCATCGCC AACGAGGACG 000560
000561 CCGCCCACGG CATCGCCAAC GAGGACGCCG CCCACGGCAT CGCCAGCGAG GACGCCGCCC ACGGAATCGC CAGCGAGGAC 000640
000641 GCCGCCCACG GCATCGCCAG CGAGGACGCC GCCCAGGGCA TCGCCAACGA GGACGCCGCC CAGGGCATCG CCAAGGAGGA 000720
000721 CGCCGTCCAC GGCATCGCCA ACGAGGACGC CGCCCAGGGC ATCGCCAACG AGGACGCCGC CCAGGGCATC GCCAAGGAGG 000800
000801 ACGCCGCCCA GGGCATCGCC AACGAGGACG CCGCCCAGGG CATCGCCAAA GAGGACGCCG CCCAGGGCAT CGCCAAGGAG 000880
000881 GACGCCGCCC AGGGCATCGC CAACGAGGGC GCCGCCCAGG GCATCGCCAA AGAGGACGCC GCCCATGGCA TCGCCAACGA 000960
000961 GGACGCCGCC CAGGGCATCG CCAACGAGGA CGCCGCCCAC GGAATCGCCA GCGAGGACGC CGCCCACGGC ATCGCCAGCG 001040
001041 AGGACGCCGT CCAGGGCATC GCCAAGGAGG ATGCCGCCCA GGGCATCGCC AACGAGGACG CCGCCCAGGG CATCGCCAAC 001120
001121 GAGGACGCCG CCCAGGGCAT CGCCAAAGAG GACGCCGCCC ACGGCATCGC CAACGAGCTG TATACGACAT CGCTAACGAG 001200
001201 GACACCCTAC AAGCCGTCGC TAACAAGTAC ACTGTACACA ACATCGCTAA TGAGGGCACT GTACAAGACA TCACCAATGA 001280
001281 GGGCGCTTTA TACGACATTG CTAATGGCAC CGACAAGGCA CGCTAACGTG GACGCTGTAC ACGACATTGC TAATGAGGAC 001360
001361 AGCGTATAAG ACATCGCTAG TAACTATCGC AAGAACAAAA AACCAAACAC CGCATATTCT CACTCATAGA TGGGAATTGA 001440
001441 ACAATGAGAT CACATGGACA CAGGAAGGGG AATATCACAC TCTGGGGACT GTTGTGGGGT TGGGGGGGGA GGGATAGCAT 001520
001521 CGGGAGATAT ACCTAATGCT AGATGATGAG TTAGTGGGTG CAGCGCACCA GCACGGCACA TGTATACATA TGTAACTAAC 001600
001601 CTGCACAATG TGCACATGTA CCCTAAAACT TAAAGTATAT ATATATAAAA AAAGACATCG CTAGTGAGCA CGCTGTATAC 001680
001681 GACATCGCTA ATGAGGACAC CATACAAGGC ATCGCTAACG ATGACGCTGT ACACAACATC ACTAATGATG ACACCGTATA 001760
001761 AGACATCGCT AATTATGACG CTGTATACGA CATCGCTAAT GACACCGTAC AAGGCACGCT AACGAGGATG CTGTACACGA 001840
001841 CATCACTAAT GAGGACAGTG TACAAGCCAT CACTAATGAG GACACTGTAT ATGGCATCGC TAACGAGGAC ACTGTACAAG 001920
001921 GCATTGCTAA CGAGGACGCT GTACACAACA TCGCTAATGA GGACACCATA TAAGACATCA CCAATGAGGA TGCTGTATAT 002000
002001 GACATCGCTA ATGGCACCCA CAAGGCATGC TAACGAGGAC GCTGTAGACG ACATTGCTTA TAAGGACACC GTACAAGA