Difference between revisions of "Lnc-NDST1-1:2"
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==Annotated Information== | ==Annotated Information== | ||
+ | ===Name=== | ||
+ | Alpha 250/ Alpha 280 | ||
+ | |||
+ | ===Characteristics=== | ||
+ | Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin. | ||
+ | |||
+ | ===Function=== | ||
+ | Regulates RPS14 transcription.. Each lncRNA can interact with the Rps14 gene loci to stimulate its expression in-trans.. Each lncRNA is transcribed through a known enhancer with putative transcription factor binding abilities, suggesting the 'enhancer' may be the transcribed RNA, which could be recruiting transcription factors to the Rps14 gene. | ||
+ | |||
+ | ===Expression=== | ||
+ | Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus. | ||
+ | |||
+ | ===Conservation=== | ||
+ | Please input conservation information here. | ||
+ | |||
+ | ===Misc=== | ||
+ | Please input misc information here. | ||
+ | |||
===Transcriptomic Nomeclature=== | ===Transcriptomic Nomeclature=== | ||
Please input transcriptomic nomeclature information here. | Please input transcriptomic nomeclature information here. | ||
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===Regulation=== | ===Regulation=== | ||
Please input regulation information here. | Please input regulation information here. | ||
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===Allelic Information and Variation=== | ===Allelic Information and Variation=== | ||
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==References== | ==References== | ||
− | + | [http://www.lncrnadb.org/alpha250alpha280/ Annotation originally sourced from lncRNAdb.] | |
{{basic| | {{basic| | ||
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sequence = <dnaseq>GCCGTATTGCGGGGCCGAGGCCTTAAAAGGCTGGACCCGCACTCACCCTTACTTCACAAGCTCCTCCCTGAAAGCAAAACGGGCCTTCTGAGACCAGGAACGAACTCAATCCCGAGTTGGCCAGGATCCAGGTGGGCCAGCCGCGCGTCTCTTGCCCGGCACCTAGCTCGGTTCCCACGGAAAGACCCCCGTCTCTCGTCCCAAGCCCCACAGGGTCCCCTCGCCGCAGGATGCCCCCCGATTGTCGCGCCCGGGC</dnaseq>| | sequence = <dnaseq>GCCGTATTGCGGGGCCGAGGCCTTAAAAGGCTGGACCCGCACTCACCCTTACTTCACAAGCTCCTCCCTGAAAGCAAAACGGGCCTTCTGAGACCAGGAACGAACTCAATCCCGAGTTGGCCAGGATCCAGGTGGGCCAGCCGCGCGTCTCTTGCCCGGCACCTAGCTCGGTTCCCACGGAAAGACCCCCGTCTCTCGTCCCAAGCCCCACAGGGTCCCCTCGCCGCAGGATGCCCCCCGATTGTCGCGCCCGGGC</dnaseq>| | ||
}} | }} | ||
− | [[Category:Antisense]] | + | [[Category:Antisense]][[Category:lnc-NDST1-1]][[Category:Transcripts]] |
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Latest revision as of 06:11, 26 August 2015
Please input one-sentence summary here.
Contents
Annotated Information
Name
Alpha 250/ Alpha 280
Characteristics
Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin.
Function
Regulates RPS14 transcription.. Each lncRNA can interact with the Rps14 gene loci to stimulate its expression in-trans.. Each lncRNA is transcribed through a known enhancer with putative transcription factor binding abilities, suggesting the 'enhancer' may be the transcribed RNA, which could be recruiting transcription factors to the Rps14 gene.
Expression
Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus.
Conservation
Please input conservation information here.
Misc
Please input misc information here.
Transcriptomic Nomeclature
Please input transcriptomic nomeclature information here.
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
Please input related labs here.
References
Annotation originally sourced from lncRNAdb.
Basic Information
Transcript ID |
lnc-NDST1-1:2 |
Source |
LNCipedia2.1 |
Same with |
, |
Classification |
antisense |
Length |
256 nt |
Genomic location |
chr5+:149829002..149829258 |
Exon number |
1 |
Exons |
149829002..149829258 |
Genome context |
|
Sequence |
000001 GCCGTATTGC GGGGCCGAGG CCTTAAAAGG CTGGACCCGC ACTCACCCTT ACTTCACAAG CTCCTCCCTG AAAGCAAAAC 000080
000081 GGGCCTTCTG AGACCAGGAA CGAACTCAAT CCCGAGTTGG CCAGGATCCA GGTGGGCCAG CCGCGCGTCT CTTGCCCGGC 000160 000161 ACCTAGCTCG GTTCCCACGG AAAGACCCCC GTCTCTCGTC CCAAGCCCCA CAGGGTCCCC TCGCCGCAGG ATGCCCCCCG 000240 000241 ATTGTCGCGC CCGGGC |