Difference between revisions of "LINC00963"
Chunlei Yu (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LINC00963 ===Approved Name=== long intergenic non-protein coding RNA 963 ===Previous Symbols=== _ ===Synonyms=== _ ===Chromosom...") |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LINC00963 | + | Approved Symbol:LINC00963 |
| − | + | ||
| − | long intergenic non-protein coding RNA 963 | + | Approved Name:long intergenic non-protein coding RNA 963 |
| − | + | ||
| − | + | RefSeq ID:NR_038955 | |
| − | = | + | |
| − | + | Ensembl ID:ENSG00000204054 | |
| + | |||
| + | LncBook ID: [https://bigd.big.ac.cn/lncbook/transcript?transid=HSALNT0155974 HSALNT0155974] | ||
| + | |||
===Chromosome=== | ===Chromosome=== | ||
9q34.11 | 9q34.11 | ||
| − | === | + | |
| − | + | ===Function=== | |
| − | = | + | LINC00963 targets on the gene FoxO3 which is participated in the FOXO signaling pathway.<ref name="ref1" /> |
| − | + | Down-regulation of LINC00963 suppress renal interstitial fibrosis (RIF) and oxidative stress (OS) of CRF by activating the FoxO signaling pathway.<ref name="ref1" /> | |
| − | === | + | |
| − | + | ===Expression=== | |
| − | + | LINC00963 is highly expressed in CRF rats.<ref name="ref1" /> | |
| − | + | ||
===Sequence=== | ===Sequence=== | ||
>gi|337299691|ref|NR_038955.1| Homo sapiens long intergenic non-protein coding RNA 963 (LINC00963), long non-coding RNA | >gi|337299691|ref|NR_038955.1| Homo sapiens long intergenic non-protein coding RNA 963 (LINC00963), long non-coding RNA | ||
<dnaseq>CCGGCCCGTCTCGGGGCCCTGAGTCATCGCCGCCCCCGGCCCCGACGCTGGCCTGCGGCGTCTGTTTGTGCAGAGCGAGGCCCCGCCGGCCGGGCTTGACGTCAGGCTGGCAGGGCCTGGAACGGCCCCGCATCGCGGCCCCCTGGGGGCAGGACGACACCGCTGGGGGCCGAGGGCAGGGCACGCCTTCGGAATCCGGCTTCGAAGCCGGCCGCCTGACCTGGGGCAAGTGCTTTCAACTCTCTGAACTTCGGTTCCTCATCTGCCAGTTGGCAGACGCTCAGCAAATCTTCCTAGACTCACGGGGCGAATTGTACAGTTGGGTAAATCGAGGCCCAGAGATGGCAAAAGGACCGTCCAAGGTCGTACAGCCACCCGGAATTACAATTCTTTTCTGCCGGGTCACACGCTGTCATCCACGTGTTACCTAAGAGAGCTTTCCAGCCTGTGCTAAGAAAACTGCCCCACATCATCTGCAGTAGGACGGGGGAGTTGGAGCCCTGGTCAGGCCACTCTGCTACTGACCACAGTTTTCTCATCTCTAAAAAGGCGCAGTAACAATATAATTACCGTATGCAGTCCCCCAGGATACAGGGTCAAAGGAGAGCACAACCATCGCAGTTGGAAGCCCATGGGGCAGCCCAGTGCAGATGCATCTGACTTACGAAACTTCAGTGACACCTGCTCTGTGCCAGACACTGAAGATGGAGCAGTGAACAGCACTGACCCAGCCTGTCCTCCTGTTGCCTGCAGGCCAGACGGAGTCTCACTCTGTCACCAGGCTGGAGTACAGTGGTGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCTCAAGTAGCTGAGATTACAGACGTGTGTCACCATGCCCTGTTAATTTTTGTTTGTTTGTTTTGTTTTTTGTTTTGTTTTGTTTCGTTTTTTGTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCCCCGATCTCGGCTCACCGCAAGCTCCGCCTCGCGGGTTCATGCCATTCTCCGGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCATCCGCCACCACACCCAGCTAATTTTTTGTATTTTTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCCCCTGACCTTGTGATCCACCCAAGGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCGGTCAATTTTTATATTTTTTGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTGTCGAACTCCCGACCTCAGGTGATTGTCGGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCGGTGGGCAGCCAGTTGTGTTCCGGGAGGAGGAGGACACCCTGGAAAGACAGTGGGGCCAGACACTGAACTGCCTTTGGAAGCAAGTAGGAGCAACAGCGAAGGTTTGCTGGCTCAGAAGCAAGGTCTCGCTGTGTTACCCTGGCTGGAGTGCAGTGGCTACTTACAGGCATGATCATAGCATACTGCAGCCTCGAACTCCTGGACTAGAGCAGTTCTCCTGCCTCAGCCTCCAGAGCAGCTGGGACTGCAGACACGCACCACAGAGCCCAGCCTGAGTCATTTTGATTCTGTAACTGGCTTCCTCTCGGCGGGCAGGCTCACACCCTCCACCCCCAGCTGGAGATGGAAGGAGGATGCTCACCGCCCATTCCTCATGCAGGCCATCGATGGAAATGTCAGACAGTGCGAGTCCACGCCTGAACACTTCTGGGGTCCGCTCTGGGACTGACACTGGCAGATCCATCGATGCCGTTCCATTGTTTGCTGACTTTCATTGATTCTATGAGAAGTCTGCAGTCTTTTGCAGCGTTGTTTTCCTATGTATAATTGTCTCCTCCCACCCCACTCACCCCAGCTGCTTTCCACATTCTCTCTCTTTGATTTTCAGCAGTCTGCCCATGATGTGCCTAAATAGGACTTTCTTTGCATTCATCTTGGCTGGGGCTCACTGAACTTTCTGAATCTGTAGATTAATTTTCTTTTTTCAATAAACCTTGGAATATTTTCAGCATAAAAAA</dnaseq> | <dnaseq>CCGGCCCGTCTCGGGGCCCTGAGTCATCGCCGCCCCCGGCCCCGACGCTGGCCTGCGGCGTCTGTTTGTGCAGAGCGAGGCCCCGCCGGCCGGGCTTGACGTCAGGCTGGCAGGGCCTGGAACGGCCCCGCATCGCGGCCCCCTGGGGGCAGGACGACACCGCTGGGGGCCGAGGGCAGGGCACGCCTTCGGAATCCGGCTTCGAAGCCGGCCGCCTGACCTGGGGCAAGTGCTTTCAACTCTCTGAACTTCGGTTCCTCATCTGCCAGTTGGCAGACGCTCAGCAAATCTTCCTAGACTCACGGGGCGAATTGTACAGTTGGGTAAATCGAGGCCCAGAGATGGCAAAAGGACCGTCCAAGGTCGTACAGCCACCCGGAATTACAATTCTTTTCTGCCGGGTCACACGCTGTCATCCACGTGTTACCTAAGAGAGCTTTCCAGCCTGTGCTAAGAAAACTGCCCCACATCATCTGCAGTAGGACGGGGGAGTTGGAGCCCTGGTCAGGCCACTCTGCTACTGACCACAGTTTTCTCATCTCTAAAAAGGCGCAGTAACAATATAATTACCGTATGCAGTCCCCCAGGATACAGGGTCAAAGGAGAGCACAACCATCGCAGTTGGAAGCCCATGGGGCAGCCCAGTGCAGATGCATCTGACTTACGAAACTTCAGTGACACCTGCTCTGTGCCAGACACTGAAGATGGAGCAGTGAACAGCACTGACCCAGCCTGTCCTCCTGTTGCCTGCAGGCCAGACGGAGTCTCACTCTGTCACCAGGCTGGAGTACAGTGGTGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCTCAAGTAGCTGAGATTACAGACGTGTGTCACCATGCCCTGTTAATTTTTGTTTGTTTGTTTTGTTTTTTGTTTTGTTTTGTTTCGTTTTTTGTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCCCCGATCTCGGCTCACCGCAAGCTCCGCCTCGCGGGTTCATGCCATTCTCCGGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCATCCGCCACCACACCCAGCTAATTTTTTGTATTTTTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCCCCTGACCTTGTGATCCACCCAAGGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCGGTCAATTTTTATATTTTTTGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTGTCGAACTCCCGACCTCAGGTGATTGTCGGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCGGTGGGCAGCCAGTTGTGTTCCGGGAGGAGGAGGACACCCTGGAAAGACAGTGGGGCCAGACACTGAACTGCCTTTGGAAGCAAGTAGGAGCAACAGCGAAGGTTTGCTGGCTCAGAAGCAAGGTCTCGCTGTGTTACCCTGGCTGGAGTGCAGTGGCTACTTACAGGCATGATCATAGCATACTGCAGCCTCGAACTCCTGGACTAGAGCAGTTCTCCTGCCTCAGCCTCCAGAGCAGCTGGGACTGCAGACACGCACCACAGAGCCCAGCCTGAGTCATTTTGATTCTGTAACTGGCTTCCTCTCGGCGGGCAGGCTCACACCCTCCACCCCCAGCTGGAGATGGAAGGAGGATGCTCACCGCCCATTCCTCATGCAGGCCATCGATGGAAATGTCAGACAGTGCGAGTCCACGCCTGAACACTTCTGGGGTCCGCTCTGGGACTGACACTGGCAGATCCATCGATGCCGTTCCATTGTTTGCTGACTTTCATTGATTCTATGAGAAGTCTGCAGTCTTTTGCAGCGTTGTTTTCCTATGTATAATTGTCTCCTCCCACCCCACTCACCCCAGCTGCTTTCCACATTCTCTCTCTTTGATTTTCAGCAGTCTGCCCATGATGTGCCTAAATAGGACTTTCTTTGCATTCATCTTGGCTGGGGCTCACTGAACTTTCTGAATCTGTAGATTAATTTTCTTTTTTCAATAAACCTTGGAATATTTTCAGCATAAAAAA</dnaseq> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Department of Nephrology, Linyi People’s Hospital, Linyi, China | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> Chen W, Zhang L, Zhou ZQ, Ren YQ, Sun LN, Man YL, Ma ZW, Wang ZK. Effects of | ||
| + | Long Non-Coding RNA LINC00963 on Renal Interstitial Fibrosis and Oxidative Stress | ||
| + | of Rats with Chronic Renal Failure via the Foxo Signaling Pathway. Cell Physiol | ||
| + | Biochem. 2018;46(2):815-828. doi: 10.1159/000488739. Epub 2018 Mar 29. PubMed | ||
| + | PMID: 29627834. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 13:02, 11 August 2019
Contents
Annotated Information
Name
Approved Symbol:LINC00963
Approved Name:long intergenic non-protein coding RNA 963
RefSeq ID:NR_038955
Ensembl ID:ENSG00000204054
LncBook ID: HSALNT0155974
Chromosome
9q34.11
Function
LINC00963 targets on the gene FoxO3 which is participated in the FOXO signaling pathway.[1] Down-regulation of LINC00963 suppress renal interstitial fibrosis (RIF) and oxidative stress (OS) of CRF by activating the FoxO signaling pathway.[1]
Expression
LINC00963 is highly expressed in CRF rats.[1]
Sequence
>gi|337299691|ref|NR_038955.1| Homo sapiens long intergenic non-protein coding RNA 963 (LINC00963), long non-coding RNA
000001 CCGGCCCGTC TCGGGGCCCT GAGTCATCGC CGCCCCCGGC CCCGACGCTG GCCTGCGGCG TCTGTTTGTG CAGAGCGAGG 000080
000081 CCCCGCCGGC CGGGCTTGAC GTCAGGCTGG CAGGGCCTGG AACGGCCCCG CATCGCGGCC CCCTGGGGGC AGGACGACAC 000160
000161 CGCTGGGGGC CGAGGGCAGG GCACGCCTTC GGAATCCGGC TTCGAAGCCG GCCGCCTGAC CTGGGGCAAG TGCTTTCAAC 000240
000241 TCTCTGAACT TCGGTTCCTC ATCTGCCAGT TGGCAGACGC TCAGCAAATC TTCCTAGACT CACGGGGCGA ATTGTACAGT 000320
000321 TGGGTAAATC GAGGCCCAGA GATGGCAAAA GGACCGTCCA AGGTCGTACA GCCACCCGGA ATTACAATTC TTTTCTGCCG 000400
000401 GGTCACACGC TGTCATCCAC GTGTTACCTA AGAGAGCTTT CCAGCCTGTG CTAAGAAAAC TGCCCCACAT CATCTGCAGT 000480
000481 AGGACGGGGG AGTTGGAGCC CTGGTCAGGC CACTCTGCTA CTGACCACAG TTTTCTCATC TCTAAAAAGG CGCAGTAACA 000560
000561 ATATAATTAC CGTATGCAGT CCCCCAGGAT ACAGGGTCAA AGGAGAGCAC AACCATCGCA GTTGGAAGCC CATGGGGCAG 000640
000641 CCCAGTGCAG ATGCATCTGA CTTACGAAAC TTCAGTGACA CCTGCTCTGT GCCAGACACT GAAGATGGAG CAGTGAACAG 000720
000721 CACTGACCCA GCCTGTCCTC CTGTTGCCTG CAGGCCAGAC GGAGTCTCAC TCTGTCACCA GGCTGGAGTA CAGTGGTGTG 000800
000801 ATCTCGGCTC ACTGCAACCT CCGCCTCCCA GGTTCAAGCG ATTCTCCTGC CTCAGCCTCT CAAGTAGCTG AGATTACAGA 000880
000881 CGTGTGTCAC CATGCCCTGT TAATTTTTGT TTGTTTGTTT TGTTTTTTGT TTTGTTTTGT TTCGTTTTTT GTTTTTTTTT 000960
000961 TTTGAGACGG AGTCTTGCTC TGTCGCCCAG GCTGGAGTGC AGTGGCCCCG ATCTCGGCTC ACCGCAAGCT CCGCCTCGCG 001040
001041 GGTTCATGCC ATTCTCCGGC CTCAGCCTCC CGAGTAGCTG GGACTACAGG CATCCGCCAC CACACCCAGC TAATTTTTTG 001120
001121 TATTTTTTTT AGTAGAGACG GGGTTTCACT GTGTTAGCCA GGATGGTCTC GATCCCCTGA CCTTGTGATC CACCCAAGGC 001200
001201 CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CGTGCCCGGT CAATTTTTAT ATTTTTTGTA GAGACAGGGT 001280
001281 TTCACCATGT TGGCCAGGCT GGTGTCGAAC TCCCGACCTC AGGTGATTGT CGGCCTTGGC CTCCCAAAGT GCTGGGATTA 001360
001361 CAGGCGTGAG CCACCGCGCC CAGCCGGTGG GCAGCCAGTT GTGTTCCGGG AGGAGGAGGA CACCCTGGAA AGACAGTGGG 001440
001441 GCCAGACACT GAACTGCCTT TGGAAGCAAG TAGGAGCAAC AGCGAAGGTT TGCTGGCTCA GAAGCAAGGT CTCGCTGTGT 001520
001521 TACCCTGGCT GGAGTGCAGT GGCTACTTAC AGGCATGATC ATAGCATACT GCAGCCTCGA ACTCCTGGAC TAGAGCAGTT 001600
001601 CTCCTGCCTC AGCCTCCAGA GCAGCTGGGA CTGCAGACAC GCACCACAGA GCCCAGCCTG AGTCATTTTG ATTCTGTAAC 001680
001681 TGGCTTCCTC TCGGCGGGCA GGCTCACACC CTCCACCCCC AGCTGGAGAT GGAAGGAGGA TGCTCACCGC CCATTCCTCA 001760
001761 TGCAGGCCAT CGATGGAAAT GTCAGACAGT GCGAGTCCAC GCCTGAACAC TTCTGGGGTC CGCTCTGGGA CTGACACTGG 001840
001841 CAGATCCATC GATGCCGTTC CATTGTTTGC TGACTTTCAT TGATTCTATG AGAAGTCTGC AGTCTTTTGC AGCGTTGTTT 001920
001921 TCCTATGTAT AATTGTCTCC TCCCACCCCA CTCACCCCAG CTGCTTTCCA CATTCTCTCT CTTTGATTTT CAGCAGTCTG 002000
002001 CCCATGATGT GCCTAAATAG GACTTTCTTT GCATTCATCT TGGCTGGGGC TCACTGAACT TTCTGAATCT GTAGATTAAT 002080
002081 TTTCTTTTTT CAATAAACCT TGGAATATTT TCAGCATAAA AAA
000081 CCCCGCCGGC CGGGCTTGAC GTCAGGCTGG CAGGGCCTGG AACGGCCCCG CATCGCGGCC CCCTGGGGGC AGGACGACAC 000160
000161 CGCTGGGGGC CGAGGGCAGG GCACGCCTTC GGAATCCGGC TTCGAAGCCG GCCGCCTGAC CTGGGGCAAG TGCTTTCAAC 000240
000241 TCTCTGAACT TCGGTTCCTC ATCTGCCAGT TGGCAGACGC TCAGCAAATC TTCCTAGACT CACGGGGCGA ATTGTACAGT 000320
000321 TGGGTAAATC GAGGCCCAGA GATGGCAAAA GGACCGTCCA AGGTCGTACA GCCACCCGGA ATTACAATTC TTTTCTGCCG 000400
000401 GGTCACACGC TGTCATCCAC GTGTTACCTA AGAGAGCTTT CCAGCCTGTG CTAAGAAAAC TGCCCCACAT CATCTGCAGT 000480
000481 AGGACGGGGG AGTTGGAGCC CTGGTCAGGC CACTCTGCTA CTGACCACAG TTTTCTCATC TCTAAAAAGG CGCAGTAACA 000560
000561 ATATAATTAC CGTATGCAGT CCCCCAGGAT ACAGGGTCAA AGGAGAGCAC AACCATCGCA GTTGGAAGCC CATGGGGCAG 000640
000641 CCCAGTGCAG ATGCATCTGA CTTACGAAAC TTCAGTGACA CCTGCTCTGT GCCAGACACT GAAGATGGAG CAGTGAACAG 000720
000721 CACTGACCCA GCCTGTCCTC CTGTTGCCTG CAGGCCAGAC GGAGTCTCAC TCTGTCACCA GGCTGGAGTA CAGTGGTGTG 000800
000801 ATCTCGGCTC ACTGCAACCT CCGCCTCCCA GGTTCAAGCG ATTCTCCTGC CTCAGCCTCT CAAGTAGCTG AGATTACAGA 000880
000881 CGTGTGTCAC CATGCCCTGT TAATTTTTGT TTGTTTGTTT TGTTTTTTGT TTTGTTTTGT TTCGTTTTTT GTTTTTTTTT 000960
000961 TTTGAGACGG AGTCTTGCTC TGTCGCCCAG GCTGGAGTGC AGTGGCCCCG ATCTCGGCTC ACCGCAAGCT CCGCCTCGCG 001040
001041 GGTTCATGCC ATTCTCCGGC CTCAGCCTCC CGAGTAGCTG GGACTACAGG CATCCGCCAC CACACCCAGC TAATTTTTTG 001120
001121 TATTTTTTTT AGTAGAGACG GGGTTTCACT GTGTTAGCCA GGATGGTCTC GATCCCCTGA CCTTGTGATC CACCCAAGGC 001200
001201 CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CGTGCCCGGT CAATTTTTAT ATTTTTTGTA GAGACAGGGT 001280
001281 TTCACCATGT TGGCCAGGCT GGTGTCGAAC TCCCGACCTC AGGTGATTGT CGGCCTTGGC CTCCCAAAGT GCTGGGATTA 001360
001361 CAGGCGTGAG CCACCGCGCC CAGCCGGTGG GCAGCCAGTT GTGTTCCGGG AGGAGGAGGA CACCCTGGAA AGACAGTGGG 001440
001441 GCCAGACACT GAACTGCCTT TGGAAGCAAG TAGGAGCAAC AGCGAAGGTT TGCTGGCTCA GAAGCAAGGT CTCGCTGTGT 001520
001521 TACCCTGGCT GGAGTGCAGT GGCTACTTAC AGGCATGATC ATAGCATACT GCAGCCTCGA ACTCCTGGAC TAGAGCAGTT 001600
001601 CTCCTGCCTC AGCCTCCAGA GCAGCTGGGA CTGCAGACAC GCACCACAGA GCCCAGCCTG AGTCATTTTG ATTCTGTAAC 001680
001681 TGGCTTCCTC TCGGCGGGCA GGCTCACACC CTCCACCCCC AGCTGGAGAT GGAAGGAGGA TGCTCACCGC CCATTCCTCA 001760
001761 TGCAGGCCAT CGATGGAAAT GTCAGACAGT GCGAGTCCAC GCCTGAACAC TTCTGGGGTC CGCTCTGGGA CTGACACTGG 001840
001841 CAGATCCATC GATGCCGTTC CATTGTTTGC TGACTTTCAT TGATTCTATG AGAAGTCTGC AGTCTTTTGC AGCGTTGTTT 001920
001921 TCCTATGTAT AATTGTCTCC TCCCACCCCA CTCACCCCAG CTGCTTTCCA CATTCTCTCT CTTTGATTTT CAGCAGTCTG 002000
002001 CCCATGATGT GCCTAAATAG GACTTTCTTT GCATTCATCT TGGCTGGGGC TCACTGAACT TTCTGAATCT GTAGATTAAT 002080
002081 TTTCTTTTTT CAATAAACCT TGGAATATTT TCAGCATAAA AAA
Labs working on this lncRNA
- Department of Nephrology, Linyi People’s Hospital, Linyi, China
References
- ↑ 1.0 1.1 1.2 Chen W, Zhang L, Zhou ZQ, Ren YQ, Sun LN, Man YL, Ma ZW, Wang ZK. Effects of Long Non-Coding RNA LINC00963 on Renal Interstitial Fibrosis and Oxidative Stress of Rats with Chronic Renal Failure via the Foxo Signaling Pathway. Cell Physiol Biochem. 2018;46(2):815-828. doi: 10.1159/000488739. Epub 2018 Mar 29. PubMed PMID: 29627834.
