Difference between revisions of "LNCPRESS2"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LNCPRESS2 ===Approved Name=== lncRNA p53 regulated and ESC associated 2 ===Previous Symbols=== _ ===Synonyms=== lncPRESS2 ===Ch...") |
Jiabao Cao (talk | contribs) |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LNCPRESS2 | + | LNCPRESS2:lncRNA p53 regulated and ESC associated 2 |
| − | + | ||
| − | lncRNA p53 regulated and ESC associated 2 | + | ===Characteristics=== |
| − | === | + | lncPRESS2, a 1,238-nt-long multi-exonic transcript annotated by Ensemble as ENSG00000249152<ref name="ref1" />. |
| − | + | ||
| − | === | + | ===Regulation=== |
| − | + | LncPRESS2 is regulated by p53-dependent alterations in chromatin state during differentiation of hESCs.<ref name="ref1" /> | |
| − | === | + | ===Expression=== |
| − | + | The expression of lncPRESS2 is coordinated with pluripotency-specific genes and repression of lncPRESS2 during differentiation is largely controlled by p53.<ref name="ref1" /> | |
| − | === | + | ===Sequence=== |
| − | NR_125920 | + | >NR_125920.1 Homo sapiens lncRNA p53 regulated and ESC associated 2 (LNCPRESS2), long non-coding RNA |
| − | == | + | <dnaseq>GCTGACTCTCTTTTCAGACTCAGCCAGCCTGCACCCAGGTGAAATAAACAGCCATGTTGCTCACGCAAAG |
| − | + | CCTGTTTGGTGGTCTCTTCAAACAGACGTGCATGAAATTTGGTGCCCTGACTCGGATCGGGGGACCTCCC | |
| − | == | + | TTGGGAGATCAATCCCCTGTACTTCTGTTCTTTGCTCCATGAGAAAGATCCACCTATGACCTCAGGTCCT |
| − | + | CAGACCAACCAGCCCAAGGAACATCTCACCAATTTTAAATCAGTTTTTCAAGTGGTACCTGAGATTCAGC | |
| − | + | ACTTCTAAAAAGCTCCAAGGTGATGAAGGTGCTGCTAGTTGGAGGCCATACTTTGAGTTGCCAGATGCTA | |
| − | + | AAAATTCAACAGATGGGAGTAGGATTTAATGGCATCAAGATTACAGCAAGAGTGTCGTCAATGTCTGAGA | |
| + | GAAAAGGCACAGGACAATTCATGTAATCTACTTTTTACCTCCTCACTATGCCAGCAGCACACTTGGAGAG | ||
| + | GAATGTTATAATGGAAGAAGCTGCCCAGTCACTGATTAAAATGTAAGAAACTGTGCTCCATTGCAGACAT | ||
| + | CTCCTGTTATGCGTTCATGAGCATATATGTGTTCTAGTATGTGTAACCTTTAAGACAATGATGGAATTTG | ||
| + | AACCATACTTTAGGACTGACACAGGTAAGAGAGTCTTGTATTAATAAGCTTCAAAATATTTTATTGTAAC | ||
| + | TTAAATTACCTCAGCAATGATACTGGGGTAGTCAGAAAAAAAATTCACCTAATTTTGAACTGATTTTTTT | ||
| + | TAAACTTTAGTAGCTTTGTGTTAGACAGATAATGTAATCTGAGTTTCAATTAACTTATTTATGGTATGGT | ||
| + | AGTAAAACTACCCTCTACACAGTGCTCTTGATAGAGTTTTTAGATATAAATAGTTTCTGTGGTGGAAGGA | ||
| + | TTTGTTTTGCCAGTTGAGTCACATGTAATGTTTGACAAACATAAGAAGATATTTGAGATGAAAAAATGAT | ||
| + | GTTATATAAAGGCACAGAAAGAGAAAATACAAGTTTGATTGAAGTAGAGGGCTTATAAAAGGAAAATAAG | ||
| + | TGTTAAAAGTGAGCTTTGGGGCAGATTGTGGAGTGCTTCATACAGATTGGGATCTATAGGAGTCTAACTG | ||
| + | GCTACTAGACTTCTTGAGACATAAAATGATTGATTTAACTGGAAGCAATATGCATGTTAGAAGGGAGAAA | ||
| + | AAACTTCTAACGGAGGTAGCAGTTCAATTAGGAAG</dnaseq> | ||
| + | ==Labs working on this lncRNA== | ||
| + | *Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Stem Cell and Development Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Cancer Epigenetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Jain AK, Xi Y, McCarthy R, Allton K, Akdemir KC, Patel LR, Aronow B, Lin C, Li | ||
| + | W, Yang L, Barton MC. LncPRESS1 Is a p53-Regulated LncRNA that Safeguards | ||
| + | Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. Mol | ||
| + | Cell. 2016 Dec 1;64(5):967-981. | ||
| + | </ref> | ||
| + | </references> | ||
Revision as of 02:59, 24 October 2017
Contents
Annotated Information
Name
LNCPRESS2:lncRNA p53 regulated and ESC associated 2
Characteristics
lncPRESS2, a 1,238-nt-long multi-exonic transcript annotated by Ensemble as ENSG00000249152[1].
Regulation
LncPRESS2 is regulated by p53-dependent alterations in chromatin state during differentiation of hESCs.[1]
Expression
The expression of lncPRESS2 is coordinated with pluripotency-specific genes and repression of lncPRESS2 during differentiation is largely controlled by p53.[1]
Sequence
>NR_125920.1 Homo sapiens lncRNA p53 regulated and ESC associated 2 (LNCPRESS2), long non-coding RNA
000001 GCTGACTCTC TTTTCAGACT CAGCCAGCCT GCACCCAGGT GAAATAAACA GCCATGTTGC TCACGCAAAG CCTGTTTGGT 000080
000081 GGTCTCTTCA AACAGACGTG CATGAAATTT GGTGCCCTGA CTCGGATCGG GGGACCTCCC TTGGGAGATC AATCCCCTGT 000160
000161 ACTTCTGTTC TTTGCTCCAT GAGAAAGATC CACCTATGAC CTCAGGTCCT CAGACCAACC AGCCCAAGGA ACATCTCACC 000240
000241 AATTTTAAAT CAGTTTTTCA AGTGGTACCT GAGATTCAGC ACTTCTAAAA AGCTCCAAGG TGATGAAGGT GCTGCTAGTT 000320
000321 GGAGGCCATA CTTTGAGTTG CCAGATGCTA AAAATTCAAC AGATGGGAGT AGGATTTAAT GGCATCAAGA TTACAGCAAG 000400
000401 AGTGTCGTCA ATGTCTGAGA GAAAAGGCAC AGGACAATTC ATGTAATCTA CTTTTTACCT CCTCACTATG CCAGCAGCAC 000480
000481 ACTTGGAGAG GAATGTTATA ATGGAAGAAG CTGCCCAGTC ACTGATTAAA ATGTAAGAAA CTGTGCTCCA TTGCAGACAT 000560
000561 CTCCTGTTAT GCGTTCATGA GCATATATGT GTTCTAGTAT GTGTAACCTT TAAGACAATG ATGGAATTTG AACCATACTT 000640
000641 TAGGACTGAC ACAGGTAAGA GAGTCTTGTA TTAATAAGCT TCAAAATATT TTATTGTAAC TTAAATTACC TCAGCAATGA 000720
000721 TACTGGGGTA GTCAGAAAAA AAATTCACCT AATTTTGAAC TGATTTTTTT TAAACTTTAG TAGCTTTGTG TTAGACAGAT 000800
000801 AATGTAATCT GAGTTTCAAT TAACTTATTT ATGGTATGGT AGTAAAACTA CCCTCTACAC AGTGCTCTTG ATAGAGTTTT 000880
000881 TAGATATAAA TAGTTTCTGT GGTGGAAGGA TTTGTTTTGC CAGTTGAGTC ACATGTAATG TTTGACAAAC ATAAGAAGAT 000960
000961 ATTTGAGATG AAAAAATGAT GTTATATAAA GGCACAGAAA GAGAAAATAC AAGTTTGATT GAAGTAGAGG GCTTATAAAA 001040
001041 GGAAAATAAG TGTTAAAAGT GAGCTTTGGG GCAGATTGTG GAGTGCTTCA TACAGATTGG GATCTATAGG AGTCTAACTG 001120
001121 GCTACTAGAC TTCTTGAGAC ATAAAATGAT TGATTTAACT GGAAGCAATA TGCATGTTAG AAGGGAGAAA AAACTTCTAA 001200
001201 CGGAGGTAGC AGTTCAATTA GGAAG
000081 GGTCTCTTCA AACAGACGTG CATGAAATTT GGTGCCCTGA CTCGGATCGG GGGACCTCCC TTGGGAGATC AATCCCCTGT 000160
000161 ACTTCTGTTC TTTGCTCCAT GAGAAAGATC CACCTATGAC CTCAGGTCCT CAGACCAACC AGCCCAAGGA ACATCTCACC 000240
000241 AATTTTAAAT CAGTTTTTCA AGTGGTACCT GAGATTCAGC ACTTCTAAAA AGCTCCAAGG TGATGAAGGT GCTGCTAGTT 000320
000321 GGAGGCCATA CTTTGAGTTG CCAGATGCTA AAAATTCAAC AGATGGGAGT AGGATTTAAT GGCATCAAGA TTACAGCAAG 000400
000401 AGTGTCGTCA ATGTCTGAGA GAAAAGGCAC AGGACAATTC ATGTAATCTA CTTTTTACCT CCTCACTATG CCAGCAGCAC 000480
000481 ACTTGGAGAG GAATGTTATA ATGGAAGAAG CTGCCCAGTC ACTGATTAAA ATGTAAGAAA CTGTGCTCCA TTGCAGACAT 000560
000561 CTCCTGTTAT GCGTTCATGA GCATATATGT GTTCTAGTAT GTGTAACCTT TAAGACAATG ATGGAATTTG AACCATACTT 000640
000641 TAGGACTGAC ACAGGTAAGA GAGTCTTGTA TTAATAAGCT TCAAAATATT TTATTGTAAC TTAAATTACC TCAGCAATGA 000720
000721 TACTGGGGTA GTCAGAAAAA AAATTCACCT AATTTTGAAC TGATTTTTTT TAAACTTTAG TAGCTTTGTG TTAGACAGAT 000800
000801 AATGTAATCT GAGTTTCAAT TAACTTATTT ATGGTATGGT AGTAAAACTA CCCTCTACAC AGTGCTCTTG ATAGAGTTTT 000880
000881 TAGATATAAA TAGTTTCTGT GGTGGAAGGA TTTGTTTTGC CAGTTGAGTC ACATGTAATG TTTGACAAAC ATAAGAAGAT 000960
000961 ATTTGAGATG AAAAAATGAT GTTATATAAA GGCACAGAAA GAGAAAATAC AAGTTTGATT GAAGTAGAGG GCTTATAAAA 001040
001041 GGAAAATAAG TGTTAAAAGT GAGCTTTGGG GCAGATTGTG GAGTGCTTCA TACAGATTGG GATCTATAGG AGTCTAACTG 001120
001121 GCTACTAGAC TTCTTGAGAC ATAAAATGAT TGATTTAACT GGAAGCAATA TGCATGTTAG AAGGGAGAAA AAACTTCTAA 001200
001201 CGGAGGTAGC AGTTCAATTA GGAAG
Labs working on this lncRNA
- Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Stem Cell and Development Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Cancer Epigenetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
