Difference between revisions of "SMILR"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== SMILR ===Approved Name=== "smooth muscle induced lncRNA, enhancer of proliferation" ===Previous Symbols=== _ ===Synonyms=== _ =...") |
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===Approved Name=== | ===Approved Name=== | ||
"smooth muscle induced lncRNA, enhancer of proliferation" | "smooth muscle induced lncRNA, enhancer of proliferation" | ||
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===Chromosome=== | ===Chromosome=== | ||
8q24.13 | 8q24.13 | ||
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===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_131202 | NR_131202 | ||
| + | ===Characteristics=== | ||
| + | The longest open reading frame(ORF) within SMILR is 57 amino acids.l | ||
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| + | ===Expression=== | ||
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| + | ===Cellular Localization=== | ||
| + | SMILR locates in the nucleus and cytoplasm <ref name="ref1" />. | ||
| + | [[File:Localization of SMILR.jpg|right|thumb|400px| <ref name="ref1" />.]] | ||
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| + | ===Function=== | ||
| + | SMILR regulates the expression of the nearby gene HAS2. Knockdown experiment shows SMILR is a driver gene and can regulate vascular smooth muscle cell proliferation <ref name="ref1" />. | ||
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| + | ===Regulation=== | ||
| + | SMILR expression can be regulated by IL1α or PDGF and it is a time-dependent manner <ref name="ref1" />. | ||
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===pubmed IDs=== | ===pubmed IDs=== | ||
27052414 | 27052414 | ||
Revision as of 14:57, 23 September 2017
Contents
Annotated Information
Approved Symbol
SMILR
Approved Name
"smooth muscle induced lncRNA, enhancer of proliferation"
Chromosome
8q24.13
RefSeq(supplied by NCBI)
NR_131202
Characteristics
The longest open reading frame(ORF) within SMILR is 57 amino acids.l
Expression
Cellular Localization
SMILR locates in the nucleus and cytoplasm [1].
[1].
Function
SMILR regulates the expression of the nearby gene HAS2. Knockdown experiment shows SMILR is a driver gene and can regulate vascular smooth muscle cell proliferation [1].
Regulation
SMILR expression can be regulated by IL1α or PDGF and it is a time-dependent manner [1].
