Difference between revisions of "CERNA1"
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | CERNA1 | + | CERNA1 (competing endogenous lncRNA 1 for miR-4707-5p and miR-4767) |
| − | |||
| − | competing endogenous lncRNA 1 for miR-4707-5p and miR-4767 | ||
| − | |||
| − | |||
===Synonyms=== | ===Synonyms=== | ||
LOC100129973 | LOC100129973 | ||
===Chromosome=== | ===Chromosome=== | ||
15q21.2 | 15q21.2 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_102751 | NR_102751 | ||
===pubmed IDs=== | ===pubmed IDs=== | ||
26887505 | 26887505 | ||
| + | ===Characteristics=== | ||
| + | CERNA1 is a 1520bp length validated long noncoding RNA. It locates in chromosome 15 (21.1) and antisense to guanine nucleotide binding protein,beta 5 (GNB5) and myosin VC (MYO5C). <ref name="ref1" /> | ||
| + | CERNA1 is only found in Homo sapiens.<ref name="ref1" /> | ||
| + | ===Expression=== | ||
| + | CERNA1 wis upregulated by ABO treatment in a dose- and time -dependent manner. | ||
===Disease=== | ===Disease=== | ||
cardiovascular disease | cardiovascular disease | ||
| + | ===Function=== | ||
| + | CERNA1 suppresses apoptosis by targeting miR-4707-5p and miR-4767 in vascular endothelial cells.<ref name="ref1" /> | ||
| + | ==Labs working on this lncRNA== | ||
| + | * Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan 250100, China. | ||
| + | * Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China. | ||
| + | * The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, 250012, China. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1">Lu, W., et al., Long Noncoding RNA LOC100129973 Suppresses Apoptosis by Targeting miR-4707-5p and miR-4767 in Vascular Endothelial Cells. Sci Rep, 2016. 6: p. 21620. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Revision as of 09:47, 15 October 2017
Contents
Annotated Information
Approved Symbol
CERNA1 (competing endogenous lncRNA 1 for miR-4707-5p and miR-4767)
Synonyms
LOC100129973
Chromosome
15q21.2
RefSeq(supplied by NCBI)
NR_102751
pubmed IDs
26887505
Characteristics
CERNA1 is a 1520bp length validated long noncoding RNA. It locates in chromosome 15 (21.1) and antisense to guanine nucleotide binding protein,beta 5 (GNB5) and myosin VC (MYO5C). [1] CERNA1 is only found in Homo sapiens.[1]
Expression
CERNA1 wis upregulated by ABO treatment in a dose- and time -dependent manner.
Disease
cardiovascular disease
Function
CERNA1 suppresses apoptosis by targeting miR-4707-5p and miR-4767 in vascular endothelial cells.[1]
Labs working on this lncRNA
- Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan 250100, China.
- Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
- The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, 250012, China.
