Difference between revisions of "LINC02231"
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RP11-766N7.4<ref name="ref1" /> | RP11-766N7.4<ref name="ref1" /> | ||
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===Characteristics=== | ===Characteristics=== | ||
Long noncoding RNA RP11-766N7.4, originally discovered by Ensembl GenomeBioinformatics, is located on the reversed strand in 12q14.3 region with a length of 447 bps.<ref name="ref1" /> | Long noncoding RNA RP11-766N7.4, originally discovered by Ensembl GenomeBioinformatics, is located on the reversed strand in 12q14.3 region with a length of 447 bps.<ref name="ref1" /> | ||
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The long noncoding RNA RP11-766N7.4 expression is negatively correlated with lymph node metastasis(P=0.000) and tumor stage (P=0.034). | The long noncoding RNA RP11-766N7.4 expression is negatively correlated with lymph node metastasis(P=0.000) and tumor stage (P=0.034). | ||
Long noncoding RNA RP11-766N7.4 knockdown promotes cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT process.<ref name="ref1" /> | Long noncoding RNA RP11-766N7.4 knockdown promotes cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT process.<ref name="ref1" /> | ||
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===Diseases=== | ===Diseases=== | ||
Esophageal squamous cell carcinoma<ref name="ref1" /> | Esophageal squamous cell carcinoma<ref name="ref1" /> | ||
Revision as of 09:24, 29 August 2017
Contents
Annotated Information
Name
LINC02231:long intergenic non-protein coding RNA 2231
RP11-766N7.4[1]
Characteristics
Long noncoding RNA RP11-766N7.4, originally discovered by Ensembl GenomeBioinformatics, is located on the reversed strand in 12q14.3 region with a length of 447 bps.[1]
Function
The long noncoding RNA RP11-766N7.4 expression is negatively correlated with lymph node metastasis(P=0.000) and tumor stage (P=0.034). Long noncoding RNA RP11-766N7.4 knockdown promotes cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT process.[1]
Diseases
Esophageal squamous cell carcinoma[1]
Expression
RT-qPCR results show that the long noncoding RNA RP11-766N7.4 expression level is remarkably lower in 50 Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the corresponding adjacent tissues.[1]
Labs working on this lncRNA
- Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.
