Difference between revisions of "LINC01930"
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EU358092 <ref name="ref1" /> | EU358092 <ref name="ref1" /> | ||
===Characteristics=== | ===Characteristics=== | ||
| − | EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 | + | EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 (chr1:98,399,030–98,407,302; GRCh37/hg19) <ref name="ref1" />. It is 869 bp in length and has two exons <ref name="ref1" />. |
| + | |||
| + | ===Function=== | ||
| + | EU358092 shows a potentially important role in the aetiology of schizophrenia, and its expression is modulated in response to psychoactive drug treatment in the human SH-SY5Y neuroblastoma cell line <ref name="ref1" />. | ||
===Expression=== | ===Expression=== | ||
[[File:EU358092 exp.jpg|right|thumb|400px|'''Comparison of MIR137 and ''EU358092'' expression in vivo''' <ref name="ref1" />.]] | [[File:EU358092 exp.jpg|right|thumb|400px|'''Comparison of MIR137 and ''EU358092'' expression in vivo''' <ref name="ref1" />.]] | ||
| − | EU358092 shows a similar expression pattern to that of MIR137 | + | EU358092 shows a similar expression pattern to that of MIR137, with highest expression restricted to the brain and pituitary gland <ref name="ref1" />. |
| − | === | + | ===Disease=== |
| − | Schizophrenia<ref name="ref1" /> | + | Schizophrenia <ref name="ref1" /> |
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Latest revision as of 06:34, 17 November 2017
Contents
Annotated Information
Name
LINC01930:long intergenic non-protein coding RNA 1930
EU358092 [1]
Characteristics
EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 (chr1:98,399,030–98,407,302; GRCh37/hg19) [1]. It is 869 bp in length and has two exons [1].
Function
EU358092 shows a potentially important role in the aetiology of schizophrenia, and its expression is modulated in response to psychoactive drug treatment in the human SH-SY5Y neuroblastoma cell line [1].
Expression
Comparison of MIR137 and EU358092 expression in vivo [1].
EU358092 shows a similar expression pattern to that of MIR137, with highest expression restricted to the brain and pituitary gland [1].
Disease
Schizophrenia [1]
Labs working on this lncRNA
- Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool L69 3BX, UK.
